Protein Alignment eIF4A and vas

DIOPT Version :10

• Sequence 1: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_723899.1
• Gene: vas / 26067080
• FlyBaseID: FBgn0283442
• Length: 661
• Species: Drosophila melanogaster
• Alignment Length: 404
• Identity: 127/404 - (31%)
• Similarity: 213/404 - (52%)
• Gaps: 27/404 - (6%)

  Fly     5 NEIPQDGPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRD 69
            |.||.....|..|:.:         .:|...:||:.::..:...|::.|:.||:.:|.....|||
  Fly   229 NNIPVKVTGSDVPQPI---------QHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRD 284

  Fly    70 VIAQAQSGTGKTATFSIAILQQI-----DTSIRECQALILAPTRELATQI--QRVVMALGEYMKV 127
            ::|.||:|:||||.|.:.||.::     :..:...|.:|::||||||.||  :....|...|:|:
  Fly   285 LMACAQTGSGKTAAFLLPILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKI 349

  Fly   128 HSHACIGGTNVREDARILESGCHVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQ 192
              ....|||:.|.....:..|||||:.||||:.|.::|..:..:..:..||||||.||..||.:.
  Fly   350 --GIVYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSED 412

  Fly   193 IQDVFK--MLPPDVQVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENW 255
            ::.:..  .:.|:.|.::.|||.|.::..::..|:::.|.:.:.........:||....|.
  Fly   413 MRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVN---- 473

  Fly   256 KLGTLCDLYDTLS--ITQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSG 318
            |......|.:.||  ...:::|..|:|..|.|...:|...|..:::|||..|..||..::.|::|
  Fly   474 KYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNG 538

  Fly   319 SSRVLITTDLLARGIDVQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFI-TDDDRRILK 382
            |.:|||.|.:.:||:|::.:..|||||:||..::|:|||||.||.|..|.|.:|. .:.||.|..
  Fly   539 SMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAA 603

  Fly   383 DIEQFYHTTIEEMP 396
            |:.:....:.:.:|
  Fly   604 DLVKILEGSGQTVP 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	126/403 (31%)
vas	NP_723899.1	SrmB	247..617	CDD:440279	121/375 (32%)