Protein Alignment eIF4A and eif4a2

DIOPT Version :9

• Sequence 1: NP_001245907.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_012818072.1
• Gene: eif4a2 / 100124955
• XenbaseID: XB-GENE-978554
• Length: 407
• Species: Xenopus tropicalis
• Alignment Length: 394
• Identity: 291/394 - (73%)
• Similarity: 354/394 - (89%)
• Gaps: 1/394 - (0%)

  Fly    11 GPASMEPEGVIESTWHEVYDNFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQ 75
            ||..|:|:|||||.|:|:.||||||||:|.||||||.|||||||||||||||||::|.|||||||
 Frog    14 GPDGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQ 78

  Fly    76 SGTGKTATFSIAILQQIDTSIRECQALILAPTRELATQIQRVVMALGEYMKVHSHACIGGTNVRE 140
            |||||||||:|:||||::..::|.|||:||||||||.|||:|::|||:||....||||||||||.
 Frog    79 SGTGKTATFAISILQQLEIDLKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRN 143

  Fly   141 DARILESGC-HVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDV 204
            :.:.|::.. |:||||||||:||:||:.|..::||:||||||||||||||||||.::|:.|..::
 Frog   144 EMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLSTNI 208

  Fly   205 QVILLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSI 269
            ||:|||||||.|||||::.|||||:.|||||||||||||||||:||::|.|||.||||||:||:|
 Frog   209 QVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTI 273

  Fly   270 TQSVIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGID 334
            ||:|||.|||||||.||::|...:|||||:||||:|::|:|||::||||||||||||||||||||
 Frog   274 TQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGID 338

  Fly   335 VQQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANI 399
            |||||||||||||:||||||||||||||||||||||||:|::|:|||:|||.||:||:||||.|:
 Frog   339 VQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNV 403

  Fly   400 ADLI 403
            ||||
 Frog   404 ADLI 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	289/392 (74%)
		DEADc	32..232	CDD:238167	139/200 (70%)
		Helicase_C	254..358	CDD:278689	82/103 (80%)
eif4a2	XP_012818072.1	PTZ00424	21..407	CDD:185609	285/385 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	232	1.000	Domainoid score	I2366
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	609	1.000	Inparanoid score	I911
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D321438at33208
OrthoFinder	1	1.000	-	-		FOG0000304
OrthoInspector	1	1.000	-	-		otm48604
Panther	1	1.100	-	-	O	PTHR24031
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R594
SonicParanoid	1	1.000	-	-		X250
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190