DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4B and UCP3

DIOPT Version :9

Sequence 1:	NP_608977.1	Gene:	Ucp4B / 33833	FlyBaseID:	FBgn0031758	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_172866.1	Gene:	UCP3 / 837973	AraportID:	AT1G14140	Length:	305	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	110/314 - (35%)
Similarity:	175/314 - (55%)	Gaps:	24/314 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KKTPPVELYLTAFASACSAEIVGYPFDMCKTRMQIQG----EIASRVGQKAKYRGLLATAMGIV- 91
            ::.|.....|.|..||..||.|.:|.|:.|||||:.|    ..|.|:|           |.|:|
plant     8 REAPTGTRILLASLSAMVAESVTFPIDLTKTRMQLHGSGSASGAHRIG-----------AFGVVS 61

  Fly    92 ---REEGLLKLYGGISAMLFRHSLFSGIKMLTYDYMREKMIVPDEDGRPQLSFLGSCISGVLAGA 153
               |:||::.||.|:|..:.||..::.|:::.|:.::..::..:.:....|......:.|..:|.
plant    62 EIARKEGVIGLYKGLSPAIIRHLFYTPIRIIGYENLKGLIVRSETNNSESLPLATKALVGGFSGV 126

  Fly   154 TASVLTNPTELIKIQMQMEGQRRLRGEPPRIHNVLQALTSIYRTGGVVGLWKGTVPNTWRSALVT 218
            .|.|:.:|.:|:|::||.:|:...:|..||....::|.|.|.::.||.|||||.:||..|:.||.
plant   127 IAQVVASPADLVKVRMQADGRLVSQGLKPRYSGPIEAFTKILQSEGVKGLWKGVLPNIQRAFLVN 191

  Fly   219 IGDVSCYDFCKRFLIAEFDLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQGRGIH 283
            :|:::|||..|.|:|.:....||.....:|::.:|:|...||.||||||:|:||     ||....
plant   192 MGELACYDHAKHFVIDKKIAEDNIFAHTLASIMSGLASTSLSCPADVVKTRMMN-----QGENAV 251

  Fly   284 YKGSLDCLSRLVREEGFLAMYKGFIPYWMRVGPASVVFWMTFEQIRRFRGSEGY 337
            |:.|.|||.:.|:.||..|::|||.|.|.|:||...|||:::|:.|...|...:
plant   252 YRNSYDCLVKTVKFEGIRALWKGFFPTWARLGPWQFVFWVSYEKFRLLAGISSF 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4B	NP_608977.1	PTZ00169	32..306	CDD:240302	96/281 (34%)
		Mito_carr	32..129	CDD:278578	33/104 (32%)
		Mito_carr	138..233	CDD:278578	35/94 (37%)
		Mito_carr	246..331	CDD:278578	38/84 (45%)
UCP3	NP_172866.1	Mito_carr	9..104	CDD:395101	33/105 (31%)
		Mito_carr	110..209	CDD:395101	36/98 (37%)
		Mito_carr	212..299	CDD:395101	40/91 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	92	1.000	Domainoid score	I2582
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	247	1.000	Inparanoid score	I1045
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004436
OrthoInspector	1	1.000	-	-		otm3431
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3722
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.920