Protein Alignment Ucp4B and UCP1

DIOPT Version :9

• Sequence 1: NP_608977.1
• Gene: Ucp4B / 33833
• FlyBaseID: FBgn0031758
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_068605.1
• Gene: UCP1 / 7350
• HGNCID: 12517
• Length: 307
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 96/295 - (32%)
• Similarity: 158/295 - (53%)
• Gaps: 16/295 - (5%)

  Fly    37 VELYLTAFASACSAEIVGYPFDMCKTRMQIQGEIASRVGQKAKYRGLLATAMGIVREEGLLKLYG 101
            |:|: :|..:||.|:::.:|.|..|.|:|:|||..:  ....:|:|:|.|...:|:.||.:|||.
Human    15 VQLF-SAGIAACLADVITFPLDTAKVRLQVQGECPT--SSVIRYKGVLGTITAVVKTEGRMKLYS 76

  Fly   102 GISAMLFRHSLFSGIKMLTYDYMREKMIVPDEDGRPQLSFLGS-CISGVLAGATASVLTNPTELI 165
            |:.|.|.|....:.:::..||.::|.:..    |:.....||| .::|:..|..|..:..|||::
Human    77 GLPAGLQRQISSASLRIGLYDTVQEFLTA----GKETAPSLGSKILAGLTTGGVAVFIGQPTEVV 137

  Fly   166 KIQMQMEGQRRLRGEPPRIHNVLQALTSIYRTGGVVGLWKGTVPNTWRSALVTIGDVSCYDFCKR 230
            |:::|  .|..|.|..||......|...|..|.|:.||||||.||..||.::...::..||..|.
Human   138 KVRLQ--AQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKE 200

  Fly   231 FLIAEFDLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQGRGIHYKGSLDCLSRLV 295
            ..:....|.|:.....|:|:.||.....:|.|.||||:|.:|.|..:      ||...:|..::.
Human   201 AFVKNNILADDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSPPGQ------YKSVPNCAMKVF 259

  Fly   296 REEGFLAMYKGFIPYWMRVGPASVVFWMTFEQIRR 330
            ..||..|.:||.:|.::|:|..:|:.::.|||::|
Human   260 TNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKR 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4B	NP_608977.1	PTZ00169	32..306	CDD:240302	86/269 (32%)
		Mito_carr	32..129	CDD:278578	31/91 (34%)
		Mito_carr	138..233	CDD:278578	33/95 (35%)
		Mito_carr	246..331	CDD:278578	29/85 (34%)
UCP1	NP_068605.1	Mito_carr	10..104	CDD:278578	31/91 (34%)
		Solcar 1	11..102		30/89 (34%)
		Mito_carr	111..206	CDD:278578	33/96 (34%)
		Solcar 2	111..201		33/91 (36%)
		Solcar 3	210..295		30/91 (33%)
		Mito_carr	215..300	CDD:278578	29/86 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D382447at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830