DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4B and Slc25a11

DIOPT Version :9

Sequence 1:	NP_608977.1	Gene:	Ucp4B / 33833	FlyBaseID:	FBgn0031758	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_071793.2	Gene:	Slc25a11 / 64201	RGDID:	708476	Length:	314	Species:	Rattus norvegicus

Alignment Length:	304	Identity:	99/304 - (32%)
Similarity:	155/304 - (50%)	Gaps:	20/304 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KKTPPVELYLTAFASACSAEIVGYPFDMCKTRMQIQGEIASRVGQKAKYRGLLATAMGIVREEGL 96
            :.:|....:|....:...|.:...|.|:.|.|||:.||.|.....|..:..|.:    |::.|||
  Rat    17 RTSPKSVKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTS----ILKAEGL 77

  Fly    97 LKLYGGISAMLFRHSLFSGIKMLTYDYMREKMIVPDEDGRPQLSFLGSCISGVLAGATASVLTNP 161
            ..:|.|:||.|.|.:.::..::..|..:.|::  ...||.|. .||...:.|:.||||.:.:..|
  Rat    78 RGIYTGLSAGLLRQATYTTTRLGIYTVLFERL--TGADGTPP-GFLLKALIGMTAGATGAFVGTP 139

  Fly   162 TELIKIQMQMEGQRRLRGEPPR-IHNVLQALTSIYRTGGVVGLWKGTVPNTWRSALVTIGDVSCY 225
            .|:..|:|..:|  ||..:..| ..||..||..|.|..||..||:|.:|...|:.:|....::.|
  Rat   140 AEVALIRMTADG--RLPADQRRGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASY 202

  Fly   226 DFCKRFLIAEFDLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQGRGI----HYKG 286
            ...|:||:......||....|.|:|.:|:.....|:|.|:||:||.|.      |.|    .||.
  Rat   203 SQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNM------RMIDGKPEYKN 261

  Fly   287 SLDCLSRLVREEGFLAMYKGFIPYWMRVGPASVVFWMTFEQIRR 330
            .||.|.::||.|||.:::|||.||:.|:||.:|:.::..||:.:
  Rat   262 GLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNK 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4B	NP_608977.1	PTZ00169	32..306	CDD:240302	88/278 (32%)
		Mito_carr	32..129	CDD:278578	26/96 (27%)
		Mito_carr	138..233	CDD:278578	32/95 (34%)
		Mito_carr	246..331	CDD:278578	35/89 (39%)
Slc25a11	NP_071793.2	Solcar 1	23..108		24/88 (27%)
		Mito_carr	24..102	CDD:395101	23/81 (28%)
		Mito_carr	116..213	CDD:395101	34/99 (34%)
		Solcar 2	117..208		31/93 (33%)
		Mito_carr	215..313	CDD:395101	37/97 (38%)
		Solcar 3	217..306		37/95 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54059
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820