DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4B and Ucp2

DIOPT Version :9

Sequence 1:	NP_608977.1	Gene:	Ucp4B / 33833	FlyBaseID:	FBgn0031758	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_062227.2	Gene:	Ucp2 / 54315	RGDID:	3932	Length:	309	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	100/301 - (33%)
Similarity:	164/301 - (54%)	Gaps:	19/301 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PPVEL--YLTAFASACSAEIVGYPFDMCKTRMQIQGEI--ASRVGQKAKYRGLLATAMGIVREEG 95
            ||...  :|.|..:||.|:::.:|.|..|.|:|||||.  .:|....|:|||:|.|.:.:||.||
  Rat    10 PPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLARTAASAQYRGVLGTILTMVRTEG 74

  Fly    96 LLKLYGGISAMLFRHSLFSGIKMLTYDYMREKMIVPDEDGRPQLSFLGS-CISGVLAGATASVLT 159
            ...||.|:.|.|.|...|:.:::..||.:::......|.     :.:|| .::|...||.|..:.
  Rat    75 PRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEH-----AGIGSRLLAGSTTGALAVAVA 134

  Fly   160 NPTELIKIQMQMEGQRRLRGEPPRIHNVLQALTSIYRTGGVVGLWKGTVPNTWRSALVTIGDVSC 224
            .||:::|::.|.:.:   .|...|..:.::|..:|.|..|:.||||||.||..|:|:|...::..
  Rat   135 QPTDVVKVRFQAQAR---AGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCTELVT 196

  Fly   225 YDFCKRFLIAEFDLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQGRGIHYKGSLD 289
            ||..|..|:....:.|:....|.:|..||....:::.|.||||:|.||....:      |..:..
  Rat   197 YDLIKDTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQ------YHSAGH 255

  Fly   290 CLSRLVREEGFLAMYKGFIPYWMRVGPASVVFWMTFEQIRR 330
            |...::|:||..|.||||:|.::|:|..:||.::|:||::|
  Rat   256 CALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4B	NP_608977.1	PTZ00169	32..306	CDD:240302	88/275 (32%)
		Mito_carr	32..129	CDD:278578	36/97 (37%)
		Mito_carr	138..233	CDD:278578	30/95 (32%)
		Mito_carr	246..331	CDD:278578	31/85 (36%)
Ucp2	NP_062227.2	Mito_carr	10..111	CDD:395101	36/100 (36%)
		Solcar 1	11..106		35/94 (37%)
		Mito_carr	112..206	CDD:395101	32/101 (32%)
		Solcar 2	114..203		30/91 (33%)
		Solcar 3	212..297		32/91 (35%)
		Mito_carr	217..299	CDD:395101	31/86 (36%)
		Purine nucleotide binding. /evidence=ECO:0000250	276..298		8/21 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54059
OrthoDB	1	1.010	-	-		D382447at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830