DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4B and slc25a27

DIOPT Version :9

Sequence 1:	NP_608977.1	Gene:	Ucp4B / 33833	FlyBaseID:	FBgn0031758	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_956635.1	Gene:	slc25a27 / 393312	ZFINID:	ZDB-GENE-040426-1290	Length:	315	Species:	Danio rerio

Alignment Length:	319	Identity:	143/319 - (44%)
Similarity:	205/319 - (64%)	Gaps:	10/319 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LEYLVTNKKTPPVELYLTAFASACSAEIVGYPFDMCKTRMQIQGEIASRVG------QKAKYRGL 83
            :.:|..|.:.|.|..:..:..:|..||:|.:|.|:.|||:|||||  .|.|      |..||||:
Zfish     1 MSHLQENSRWPRVSKFTLSACAAAVAELVTFPLDLTKTRLQIQGE--GRSGKNGGSVQTQKYRGM 63

  Fly    84 LATAMGIVREEGLLKLYGGISAMLFRHSLFSGIKMLTYDYMREKMIVPDEDGRPQLSFLGSCISG 148
            |:||.|||||||.|||:.|::..::||.::||.:||.|:.|||.::...|||  ......:.|:.
Zfish    64 LSTAAGIVREEGPLKLWQGVTPAIYRHIVYSGGRMLAYEQMRESVLGKSEDG--IFPVWKAVIAS 126

  Fly   149 VLAGATASVLTNPTELIKIQMQMEGQRRLRGEPPRIHNVLQALTSIYRTGGVVGLWKGTVPNTWR 213
            :::||....:.:||:|:|:||||||:|||.|:|||:..|..|.|.|...||:.|||.|.|||..|
Zfish   127 MISGALGQFIASPTDLVKVQMQMEGRRRLEGKPPRVRGVYHAFTKIVAQGGIRGLWAGWVPNVQR 191

  Fly   214 SALVTIGDVSCYDFCKRFLIAEFDLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQ 278
            :|||.:||:..||..|.||:....:.||.....::::.:|:..|.:..||||||:|:||||.|..
Zfish   192 AALVNLGDLMTYDTVKHFLLRNTSIPDNSICHGLSSICSGLVAATMGTPADVVKTRVMNQPRDSN 256

  Fly   279 GRGIHYKGSLDCLSRLVREEGFLAMYKGFIPYWMRVGPASVVFWMTFEQIRRFRGSEGY 337
            |||:.|:.|.|||.:.||.|||.::||||:|.|.|:.|.|:.||:||||:||..|...:
Zfish   257 GRGLLYRNSTDCLVQSVRREGFFSLYKGFLPTWFRMAPWSLTFWLTFEQLRRAMGISSF 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4B	NP_608977.1	PTZ00169	32..306	CDD:240302	124/279 (44%)
		Mito_carr	32..129	CDD:278578	47/102 (46%)
		Mito_carr	138..233	CDD:278578	43/94 (46%)
		Mito_carr	246..331	CDD:278578	43/84 (51%)
slc25a27	NP_956635.1	Mito_carr	13..112	CDD:278578	46/100 (46%)
		PTZ00169	16..310	CDD:240302	138/297 (46%)
		Mito_carr	118..213	CDD:278578	44/94 (47%)
		Mito_carr	217..311	CDD:278578	46/93 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594808
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004436
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3722
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.800