DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ucp4B and CG7514

DIOPT Version :9

Sequence 1:	NP_608977.1	Gene:	Ucp4B / 33833	FlyBaseID:	FBgn0031758	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_647923.1	Gene:	CG7514 / 38571	FlyBaseID:	FBgn0035567	Length:	301	Species:	Drosophila melanogaster

Alignment Length:	311	Identity:	93/311 - (29%)
Similarity:	150/311 - (48%)	Gaps:	30/311 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LEYLVTNKKTPPVELYLTAFASACSAEIVGYPFDMCKTRMQIQGEIASRVGQKAKYRGLLATAMG 89
            :.|.:..|..|...:|:....:......:..|.|:.|||||    |::..|:   |:......:.
  Fly     1 MAYSIEKKSIPGYMMYINGGLAGMLGTCIVQPLDLVKTRMQ----ISATTGE---YKSSFDCLLK 58

  Fly    90 IVREEGLLKLYGGISAMLFRHSLFSGIKMLTY----DYMREKMIVPDEDGRPQLSFLGSCISGVL 150
            :.:.||:|.||.|:||.|.|.:.::..:|..|    |..|::...|.       :.|.|...|:|
  Fly    59 VFKNEGILALYNGLSAGLMRQATYTTARMGFYQMEIDAYRKQFNAPP-------TVLASMGMGIL 116

  Fly   151 AGATASVLTNPTELIKIQMQMEGQRRLRGEPPRIHNVLQALTSIYRTGGVVGLWKGTVPNTWRSA 215
            |||..::..||.|:..|:| |...|....|......||.|...|.:..||:.||||.:|...|:.
  Fly   117 AGAFGAMFGNPAEVALIRM-MSDNRLPPAERRNYTGVLNAFVRIVKDEGVITLWKGCMPTVGRAM 180

  Fly   216 LVTIGDVSCYDFCKRFLIAEF-DLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQG 279
            :|.:..::.|...|    |.| :......:...|||.:|:...|.|:|.|:.|:||..|.|.|
  Fly   181 IVNMVQLASYSQLK----AAFSEYFSGLSLHIAAAMMSGLLTTIASMPLDMAKTRIQQQKTAE-- 239

  Fly   280 RGIHYKGSLDCLSRLVREEGFLAMYKGFIPYWMRVGPASVVFWMTFEQIRR 330
                |||::|.|.::.:.||..:::|||.||..|:||.:|..::..||:.:
  Fly   240 ----YKGTMDVLMKVSKNEGIASLWKGFTPYLCRLGPHTVFAFIFLEQLTK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4B	NP_608977.1	PTZ00169	32..306	CDD:240302	81/278 (29%)
		Mito_carr	32..129	CDD:278578	27/100 (27%)
		Mito_carr	138..233	CDD:278578	30/94 (32%)
		Mito_carr	246..331	CDD:278578	32/85 (38%)
CG7514	NP_647923.1	PTZ00169	16..287	CDD:240302	90/296 (30%)
		Mito_carr	19..90	CDD:278578	21/77 (27%)
		Mito_carr	104..201	CDD:278578	33/108 (31%)
		Mito_carr	207..284	CDD:278578	31/82 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441670
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840