Protein Alignment Ucp4B and SLC25A34

DIOPT Version :10

• Sequence 1: NP_608977.1
• Gene: Ucp4B / 33833
• FlyBaseID: FBgn0031758
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_997231.1
• Gene: SLC25A34 / 284723
• HGNCID: 27653
• Length: 304
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 92/306 - (30%)
• Similarity: 158/306 - (51%)
• Gaps: 21/306 - (6%)

  Fly    35 PPVELYLTAFASACSAEIVGYPFDMCKTRMQIQGEIASRVGQKAKYRGLLATAMGIVREEGLLKL 99
            |.|:|.|.| ::.|.|.:...|.::.|||:|:|||:.:|......|.|.:|:...:.|.:||..|
Human     6 PAVDLVLGA-SACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLWGL 69

  Fly   100 YGGISAMLFRHSLFSGIKMLTYDYMREKMIVPDEDGRPQLSFLGSCISGVLAGATASVLTNPTEL 164
            ..|::|.|....|.:|::...|....:..:. .:.|       |:.::|.:|||..:.:.:|..|
Human    70 QKGLAAGLLYQGLMNGVRFYCYSLACQAGLT-QQPG-------GTVVAGAVAGALGAFVGSPAYL 126

  Fly   165 IKIQMQMEGQRRLR-GEPPRIHNVLQALTSIYRTGGVVGLWK---GTVPNTW---RSALVTIGDV 222
            ||.|:|.:....:. |.......||.||.:|:|..|::|||:   |.||...   .:.|.|....
Human   127 IKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLATFASA 191

  Fly   223 SCYDFCKRFLIAEFDLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQGRGIHYKGS 287
            ..:...:::|..     |:..|.....|.:.:|..::..|.|||.:|:.|||.|..|||..|.|.
Human   192 KAWVQKQQWLPE-----DSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGL 251

  Fly   288 LDCLSRLVREEGFLAMYKGFIPYWMRVGPASVVFWMTFEQIRRFRG 333
            .||:.::.|:||.||:|||..|.::|:||.:::..:.::::|:..|
Human   252 TDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKLAG 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4B	NP_608977.1	Mito_carr	32..129	CDD:395101	29/93 (31%)
		Mito_carr	138..233	CDD:395101	27/101 (27%)
		Mito_carr	246..331	CDD:395101	31/84 (37%)
SLC25A34	NP_997231.1	Mito_carr	2..91	CDD:395101	28/85 (33%)
		Solcar 1	4..97		29/91 (32%)
		Solcar 2	101..194		28/99 (28%)
		Mito_carr	<119..197	CDD:395101	22/77 (29%)
		Mito_carr	203..295	CDD:395101	33/96 (34%)
		Solcar 3	204..295		33/90 (37%)