DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ucp4B and SLC25A30

DIOPT Version :10

Sequence 1:NP_608977.1 Gene:Ucp4B / 33833 FlyBaseID:FBgn0031758 Length:337 Species:Drosophila melanogaster
Sequence 2:XP_005266378.1 Gene:SLC25A30 / 253512 HGNCID:27371 Length:293 Species:Homo sapiens


Alignment Length:260 Identity:89/260 - (34%)
Similarity:138/260 - (53%) Gaps:21/260 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 SACSAEIVGYPFDMCKTRMQIQGEIASRVGQKAKYRGLLATAMGIVREEGLLKLYGGISAMLFRH 110
            ::.:||...:|.|:.|||:||||:......::.:|||:|...:.|.|||||..||.||:..:.|.
Human    15 ASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSGIAPAMLRQ 79

  Fly   111 SLFSGIKMLTYDYMREKMIVPDEDGRPQLSFLGSCISGVLAGATASVLTNPTELIKIQMQMEGQR 175
            :.:..||:.||..::...|...||....:    :.|.|:|:|..:|.:.|||:::||:||.:.  
Human    80 ASYGTIKIGTYQSLKRLFIERPEDETLPI----NVICGILSGVISSTIANPTDVLKIRMQAQS-- 138

  Fly   176 RLRGEPPRIHNVLQA-----LTSIYRTGGVVGLWKGTVPNTWRSALVTIGDVSCYDFCKRFLIAE 235
                      |.:|.     ..:||:..|..|||||......|:|:|...::..||..|:.||..
Human   139 ----------NTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILS 193

  Fly   236 FDLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQGRGIHYKGSLDCLSRLVREEGF 300
            ..:.|.....|:::.|.|:|.|:.|.|.|||::|:|||.....||...|.|:||||.:|...|.|
Human   194 GLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTGTLDCLLQLTVLESF 258

  Fly   301  300
            Human   259  258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ucp4BNP_608977.1 Mito_carr 32..129 CDD:395101 30/82 (37%)
Mito_carr 138..233 CDD:395101 28/99 (28%)
Mito_carr 246..331 CDD:395101 25/55 (45%)
SLC25A30XP_005266378.1 Mito_carr 5..100 CDD:395101 31/84 (37%)
Mito_carr 102..191 CDD:395101 30/104 (29%)
Mito_carr 199..>252 CDD:395101 22/52 (42%)

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