Protein Alignment Ucp4C and SLC25A27

DIOPT Version :9

• Sequence 1: NP_608976.1
• Gene: Ucp4C / 33832
• FlyBaseID: FBgn0031757
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_004268.3
• Gene: SLC25A27 / 9481
• HGNCID: 21065
• Length: 323
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 122/326 - (37%)
• Similarity: 188/326 - (57%)
• Gaps: 14/326 - (4%)

  Fly    17 EEEPRFPPTNVADPLTARNLFQLYVNTFIGANLAESCVFPLDVAKTRMQVDGEQA-KKTG---KA 77
            |||.|..|.....|..::     ::.:...|.:||...||||:.|||:|:.||.| .:.|   :.
Human     5 EEEERLLPLTQRWPRASK-----FLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARE 64

  Fly    78 MPTFRA---TLTNMIRVEGFKSLYAGFSAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKI 139
            ...:|.   |...:|..|||..|:.|.:..:.|:.:::..|:|.|:..|.....::|  :|...:
Human    65 SAPYRGMVRTALGIIEEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSE--DEHYPL 127

  Fly   140 YMALGCSFTAGCIAQALANPFDIVKVRMQTEGRRRQLGYDVRVNSMVQAFVDIYRRGGLPSMWKG 204
            :.::.....||.|.|.||||.|:|||:||.||:|:..|..:|...:..||..|...||:..:|.|
Human   128 WKSVIGGMMAGVIGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAG 192

  Fly   205 VGPSCMRACLMTTGDVGSYDISKRTFKRLLDLEEGLPLRFVSSMCAGLTASVLSTPADVIKSRMM 269
            ..|:..||.|:..||:.:||..|........||:.:....:||:|:||.||:|.|||||||||:|
Human   193 WVPNIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIM 257

  Fly   270 NQPVDESGKNLYYKNSLDCVRKLVREEGVLTLYKGLMPTWFRLGPFSVLFWLSVEQLRQWEGQSG 334
            |||.|:.|:.|.||:|.||:.:.|:.||.::||||.:|:|.|:.|:|::|||:.|::|:..|.|.
Human   258 NQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIREMSGVSP 322

  Fly   335 F 335
            |
Human   323 F 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	26/81 (32%)
		Mito_carr	137..232	CDD:278578	35/94 (37%)
		Mito_carr	237..329	CDD:278578	47/91 (52%)
SLC25A27	NP_004268.3	Mito_carr	20..118	CDD:365909	28/102 (27%)
		Solcar 1	21..115		28/98 (29%)
		Mito_carr	125..219	CDD:365909	35/93 (38%)
		Solcar 2	125..217		35/91 (38%)
		Solcar 3	226..317		46/90 (51%)
		Mito_carr	227..317	CDD:365909	46/89 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158856
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D477054at33208
OrthoFinder	1	1.000	-	-		FOG0004436
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.810