DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ucp4C and DIC1

DIOPT Version :9

Sequence 1:	NP_608976.1	Gene:	Ucp4C / 33832	FlyBaseID:	FBgn0031757	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_013452.1	Gene:	DIC1 / 851063	SGDID:	S000004340	Length:	298	Species:	Saccharomyces cerevisiae

Alignment Length:	280	Identity:	84/280 - (30%)
Similarity:	140/280 - (50%)	Gaps:	31/280 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 PLDVAKTRMQVDGEQAKKTGKAMPTFRATLTNMIRVEGFKSLYAGFSAMVTRNFIFNSLRVVLYD 120
            |||:||.|:|.       .....||....|.:::..||...||:|.||.|.|...:.::|...||
Yeast    33 PLDLAKVRLQA-------APMPKPTLFRMLESILANEGVVGLYSGLSAAVLRQCTYTTVRFGAYD 90

  Fly   121 VFRRPFLYQNERNEEVLKIYMALGCSFTAGCIAQALANPFDIVKVRMQTE-----GRRRQLGYDV 180
            :.:...:    ..|::..:...|.||..:|.|.....|..|:|.:|||.:     .:||
Yeast    91 LLKENVI----PREQLTNMAYLLPCSMFSGAIGGLAGNFADVVNIRMQNDSALEAAKRR------ 145

  Fly   181 RVNSMVQAFVDIYR-RGGLPSMWKGVGPSCMRACLMTTGDVGSYDISKRTFKRLLDLEEGLP-LR 243
            ...:.:.....||| .|||.:::.|..|:.:|..|||...|.:||:.|......||.:.... ..
Yeast   146 NYKNAIDGVYKIYRYEGGLKTLFTGWKPNMVRGILMTASQVVTYDVFKNYLVTKLDFDASKNYTH 210

  Fly   244 FVSSMCAGLTASVLSTPADVIKSRMMNQPVDESGKNLYYKNSLDCVRKLVREEGVLTLYKGLMPT 308
            ..:|:.|||.|:.:.:||||:|:|:||...|       ::.:|..:...||:||...:::|.:|:
Yeast   211 LTASLLAGLVATTVCSPADVMKTRIMNGSGD-------HQPALKILADAVRKEGPSFMFRGWLPS 268

  Fly   309 WFRLGPFSVLFWLSVEQLRQ 328
            :.|||||::|.:.::|||::
Yeast   269 FTRLGPFTMLIFFAIEQLKK 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	22/67 (33%)
		Mito_carr	137..232	CDD:278578	29/100 (29%)
		Mito_carr	237..329	CDD:278578	30/93 (32%)
DIC1	NP_013452.1	Mito_carr	20..94	CDD:395101	22/67 (33%)
		Mito_carr	100..200	CDD:395101	30/105 (29%)
		Mito_carr	203..289	CDD:395101	30/93 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51917
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820