Protein Alignment Ucp4C and UCP3

DIOPT Version :10

• Sequence 1: NP_608976.1
• Gene: Ucp4C / 33832
• FlyBaseID: FBgn0031757
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_003347.1
• Gene: UCP3 / 7352
• HGNCID: 12519
• Length: 312
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 106/299 - (35%)
• Similarity: 163/299 - (54%)
• Gaps: 30/299 - (10%)

  Fly    44 FIGAN----LAESCVFPLDVAKTRMQVDGE-QAKKTGKAMPTFR---ATLTNMIRVEGFKSLYAG 100
            |:||.    .|:...||||.||.|:|:.|| ||.:|.: :..:|   .|:..|:|.||..|.|.|
Human    17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTAR-LVQYRGVLGTILTMVRTEGPCSPYNG 80

  Fly   101 FSAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKIYMALGCSFTAGCIAQALANPFDIVKV 165
            ..|.:.|...|.|:|:.|||..::.:..:...|..:....:| ||  |.|.:|...|.|.|:|||
Human    81 LVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILA-GC--TTGAMAVTCAQPTDVVKV 142

  Fly   166 RMQTE---GRRRQLGYDVRVNSMVQAFVDIYRRGGLPSMWKGVGPSCMRACLMTTGDVGSYDISK 227
            |.|..   |..|.   |.:.:..:.|:..|.|..|:..:|||..|:.||..::...:|.:|||.|
Human   143 RFQASIHLGPSRS---DRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILK 204

  Fly   228 RTFKRLLD---LEEGLPLRFVSSMCAGLTASVLSTPADVIKSRMMNQPVDESGKNLYYKNSLDCV 289
               ::|||   |.:..|..|||:..||..|:|:::|.||:|:|.||.|..:      |.:.|||:
Human   205 ---EKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQ------YFSPLDCM 260

  Fly   290 RKLVREEGVLTLYKGLMPTWFRLGPFSVLFWLSVEQLRQ 328
            .|:|.:||....|||..|::.|||.::|:.:::.|||::
Human   261 IKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:395101	31/78 (40%)
		Mito_carr	137..232	CDD:395101	32/97 (33%)
		Mito_carr	237..329	CDD:395101	35/92 (38%)
UCP3	NP_003347.1	Mito_carr	10..110	CDD:395101	34/93 (37%)
		Solcar 1	11..105		34/88 (39%)
		Mito_carr	112..210	CDD:395101	35/106 (33%)
		Solcar 2	114..206		32/100 (32%)
		Mito_carr	214..303	CDD:395101	35/92 (38%)
		Solcar 3	215..300		35/91 (38%)
		Purine nucleotide binding. /evidence=ECO:0000250	279..301		7/21 (33%)