DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4C and slc25a35

DIOPT Version :9

Sequence 1:	NP_608976.1	Gene:	Ucp4C / 33832	FlyBaseID:	FBgn0031757	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_001092917.1	Gene:	slc25a35 / 557185	ZFINID:	ZDB-GENE-060526-142	Length:	298	Species:	Danio rerio

Alignment Length:	300	Identity:	81/300 - (27%)
Similarity:	141/300 - (47%)	Gaps:	28/300 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 GANLAESCVF--PLDVAKTRMQVDGEQAKKTGKAMPTFRATLTNMI-------RVEGFKSLYAGF 101
            |.....:|.|  ||:|.|||||:.||.     |:..|::....|:.       :::|...|..|.
Zfish     7 GVAACGACFFTNPLEVVKTRMQLQGEL-----KSRGTYQVYYRNVFHAFYTIGKIDGLAGLQKGL 66

  Fly   102 SAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKIYMALGCSFTAGCIAQALANPFDIVKVR 166
            ...:...|..|.:|:..|.:.........:......|..::   ...||.:...:.:|..:||..
Zfish    67 VPGLVYQFFMNGVRLGSYALTESLGYIHTDGRVSATKSTVS---GAIAGVVGAVMGSPIYLVKTH 128

  Fly   167 MQTEGRRR-QLGYDVRVNSMVQAFVDIYRRGGLPSMWKGVGPSCMRACLMTTGDVGSYDISKRTF 230
            :|::.... .:|:..:...|..|...|:::.|:..:|:|...:..|..:.:...:.::..||...
Zfish   129 LQSQSTSSIAVGHQYKHRGMTNALFAIHKQHGILGLWRGASAAIPRVSVGSAAQLATFSASKEMV 193

  Fly   231 KRLLDLEEGLPLRFVSSMCAGLTASVL----STPADVIKSRMMNQPVDESGKNLYYKNSLDCVRK 291
            ..|....||   .::.::.||:.:||:    .||.||:.:|:.|||||..||.:.|:..:||..|
Zfish   194 NDLQVFSEG---SWLIALSAGMISSVVVVLAMTPFDVVSTRLYNQPVDHLGKGMLYRGFVDCFSK 255

  Fly   292 LVREEGVLTLYKGLMPTWFRLGP---FSVLFWLSVEQLRQ 328
            .:::||:..|||||..::|||||   .|:|||..:..|.|
Zfish   256 TLKKEGMTGLYKGLGASYFRLGPHTILSLLFWNELRCLHQ 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	22/83 (27%)
		Mito_carr	137..232	CDD:278578	17/95 (18%)
		Mito_carr	237..329	CDD:278578	39/98 (40%)
slc25a35	NP_001092917.1	Solcar 1	1..90		23/87 (26%)
		PTZ00169	2..291	CDD:240302	79/294 (27%)
		Mito_carr	2..84	CDD:278578	22/81 (27%)
		Mito_carr	97..195	CDD:278578	17/100 (17%)
		Solcar 2	99..192		17/95 (18%)
		Mito_carr	200..286	CDD:278578	35/88 (40%)
		Solcar 3	202..293		37/93 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910