DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ucp4C and ucp2

DIOPT Version :9

Sequence 1:	NP_608976.1	Gene:	Ucp4C / 33832	FlyBaseID:	FBgn0031757	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_571251.1	Gene:	ucp2 / 555812	ZFINID:	ZDB-GENE-990708-8	Length:	310	Species:	Danio rerio

Alignment Length:	295	Identity:	97/295 - (32%)
Similarity:	160/295 - (54%)	Gaps:	24/295 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 FIGANLAESCV-----FPLDVAKTRMQVDGEQAKKT--GKAMPTFR---ATLTNMIRVEGFKSLY 98
            ||||..| :|:     ||||.||.|:|:.||....|  |:....:|   .|::.|:||||.:|||
Zfish    17 FIGAGTA-ACIADLFTFPLDTAKVRLQIQGENKASTNMGRGPVKYRGVFGTISTMVRVEGPRSLY 80

  Fly    99 AGFSAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKIYMALGCSFTAGCIAQALANPFDIV 163
            :|..|.:.|...|.|:|:.|||..::  .|....:...:...:..||  |.|.:|.|:|.|.|:|
Zfish    81 SGLVAGLQRQMSFASVRIGLYDSVKQ--FYTKGSDHAGIGSRLMAGC--TTGAMAVAVAQPTDVV 141

  Fly   164 KVRMQTEGRRRQLGYDVRVNSMVQAFVDIYRRGGLPSMWKGVGPSCMRACLMTTGDVGSYDISKR 228
            |||.|.:   ...|...|.:|.:.|:..|.:..|...:|||.||:..|..::...::.:||:.|.
Zfish   142 KVRFQAQ---VSAGSSKRYHSTMDAYRTIAKEEGFRGLWKGTGPNITRNAIVNCTELVTYDLIKD 203

  Fly   229 TFKRLLDLEEGLPLRFVSSMCAGLTASVLSTPADVIKSRMMNQPVDESGKNLYYKNSLDCVRKLV 293
            ...:...:.:.||..|.|:..||...:::::|.||:|:|.||....:      |.::|:|...::
Zfish   204 ALLKSSLMTDDLPCHFTSAFGAGFCTTIIASPVDVVKTRYMNSAQGQ------YSSALNCAVAML 262

  Fly   294 REEGVLTLYKGLMPTWFRLGPFSVLFWLSVEQLRQ 328
            .:||....|||.||::.|||.::|:.:::.|||::
Zfish   263 TKEGPKAFYKGFMPSFLRLGSWNVVMFVTYEQLKR 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	33/84 (39%)
		Mito_carr	137..232	CDD:278578	29/94 (31%)
		Mito_carr	237..329	CDD:278578	30/92 (33%)
ucp2	NP_571251.1	Mito_carr	10..112	CDD:278578	38/97 (39%)
		Solcar 1	11..107		37/92 (40%)
		PTZ00169	17..300	CDD:240302	97/295 (33%)
		Mito_carr	113..209	CDD:278578	29/100 (29%)
		Solcar 2	115..204		29/93 (31%)
		Solcar 3	213..298		30/91 (33%)
		Mito_carr	218..300	CDD:278578	28/86 (33%)
		Purine nucleotide binding. /evidence=ECO:0000250	277..299		7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1126848at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820