DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4C and slc25a27

DIOPT Version :9

Sequence 1:	NP_608976.1	Gene:	Ucp4C / 33832	FlyBaseID:	FBgn0031757	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_956635.1	Gene:	slc25a27 / 393312	ZFINID:	ZDB-GENE-040426-1290	Length:	315	Species:	Danio rerio

Alignment Length:	326	Identity:	118/326 - (36%)
Similarity:	189/326 - (57%)	Gaps:	20/326 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IEEEPRFPPTNVADPLTARNLFQLYVNTFIGANLAESCVFPLDVAKTRMQVDGE-QAKKTGKAMP 79
            ::|..|:|..:            .:..:...|.:||...||||:.|||:|:.|| ::.|.|.::.
Zfish     4 LQENSRWPRVS------------KFTLSACAAAVAELVTFPLDLTKTRLQIQGEGRSGKNGGSVQ 56

  Fly    80 TFR-----ATLTNMIRVEGFKSLYAGFSAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKI 139
            |.:     :|...::|.||...|:.|.:..:.|:.:::..|::.|:..|...|.::|  :.:..:
Zfish    57 TQKYRGMLSTAAGIVREEGPLKLWQGVTPAIYRHIVYSGGRMLAYEQMRESVLGKSE--DGIFPV 119

  Fly   140 YMALGCSFTAGCIAQALANPFDIVKVRMQTEGRRRQLGYDVRVNSMVQAFVDIYRRGGLPSMWKG 204
            :.|:..|..:|.:.|.:|:|.|:|||:||.|||||..|...||..:..||..|..:||:..:|.|
Zfish   120 WKAVIASMISGALGQFIASPTDLVKVQMQMEGRRRLEGKPPRVRGVYHAFTKIVAQGGIRGLWAG 184

  Fly   205 VGPSCMRACLMTTGDVGSYDISKRTFKRLLDLEEGLPLRFVSSMCAGLTASVLSTPADVIKSRMM 269
            ..|:..||.|:..||:.:||..|....|...:.:......:||:|:||.|:.:.|||||:|:|:|
Zfish   185 WVPNVQRAALVNLGDLMTYDTVKHFLLRNTSIPDNSICHGLSSICSGLVAATMGTPADVVKTRVM 249

  Fly   270 NQPVDESGKNLYYKNSLDCVRKLVREEGVLTLYKGLMPTWFRLGPFSVLFWLSVEQLRQWEGQSG 334
            |||.|.:|:.|.|:||.||:.:.||.||..:||||.:|||||:.|:|:.|||:.||||:..|.|.
Zfish   250 NQPRDSNGRGLLYRNSTDCLVQSVRREGFFSLYKGFLPTWFRMAPWSLTFWLTFEQLRRAMGISS 314

  Fly   335 F 335
            |
Zfish   315 F 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	24/80 (30%)
		Mito_carr	137..232	CDD:278578	36/94 (38%)
		Mito_carr	237..329	CDD:278578	47/91 (52%)
slc25a27	NP_956635.1	Mito_carr	13..112	CDD:278578	27/110 (25%)
		PTZ00169	16..310	CDD:240302	112/295 (38%)
		Mito_carr	118..213	CDD:278578	36/94 (38%)
		Mito_carr	217..311	CDD:278578	47/93 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594809
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D477054at33208
OrthoFinder	1	1.000	-	-		FOG0004436
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45618
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.810