DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4C and Slc25a30

DIOPT Version :9

Sequence 1:	NP_608976.1	Gene:	Ucp4C / 33832	FlyBaseID:	FBgn0031757	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_001013205.1	Gene:	Slc25a30 / 361074	RGDID:	1359702	Length:	291	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	91/282 - (32%)
Similarity:	156/282 - (55%)	Gaps:	15/282 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 AESCVFPLDVAKTRMQVDGEQAKKTGKAMPTFRATLTNMIRV---EGFKSLYAGFSAMVTRNFIF 111
            ||...||:|:.|||:|:.|:......:.: .:|..|..::|:   ||.::||:|.:..:.|...:
  Rat    19 AECGTFPIDLTKTRLQIQGQTNDAKFREI-RYRGMLHALMRIGREEGLRALYSGIAPAMLRQASY 82

  Fly   112 NSLRVVLYDVFRRPFLYQNERNEEVLKIYMALGCSFTAGCIAQALANPFDIVKVRMQTEGRRRQL 176
            .::::..|...:|  |......:|.|.|.:.  |...:|.|:.|:|||.|::|:|||.:....|.
  Rat    83 GTIKIGTYQSLKR--LAVERPEDETLLINVV--CGILSGVISSAIANPTDVLKIRMQAQNSAVQG 143

  Fly   177 GYDVRVNSMVQAFVDIYRRGGLPSMWKGVGPSCMRACLMTTGDVGSYDISKRTFKRLLDLEEGLP 241
            |       |:..|:.||::.|...:||||..:..||.::...::..|||:|:.......:.:.:.
  Rat   144 G-------MIGNFISIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVS 201

  Fly   242 LRFVSSMCAGLTASVLSTPADVIKSRMMNQPVDESGKNLYYKNSLDCVRKLVREEGVLTLYKGLM 306
            ..|:||...||..::.|.|.||:::|||||.....|:...||.:|||:.:..:.||...||||..
  Rat   202 THFLSSFTCGLVGALASNPVDVVRTRMMNQRDLRDGRCSGYKGTLDCLLQTWKNEGFFALYKGFW 266

  Fly   307 PTWFRLGPFSVLFWLSVEQLRQ 328
            |.|.||||::::|:|:.|||::
  Rat   267 PNWLRLGPWNIIFFLTYEQLKK 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	20/76 (26%)
		Mito_carr	137..232	CDD:278578	31/94 (33%)
		Mito_carr	237..329	CDD:278578	37/92 (40%)
Slc25a30	NP_001013205.1	Solcar 1	7..96		21/79 (27%)
		PTZ00169	9..289	CDD:240302	91/282 (32%)
		Solcar 2	104..189		32/93 (34%)
		Solcar 3	198..289		37/91 (41%)
		Mito_carr	199..289	CDD:395101	37/90 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1126848at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103926
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720