Protein Alignment Ucp4C and SLC25A34

DIOPT Version :10

• Sequence 1: NP_608976.1
• Gene: Ucp4C / 33832
• FlyBaseID: FBgn0031757
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_997231.1
• Gene: SLC25A34 / 284723
• HGNCID: 27653
• Length: 304
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 91/311 - (29%)
• Similarity: 157/311 - (50%)
• Gaps: 37/311 - (11%)

  Fly    41 VNTFIGAN-LAESCVF--PLDVAKTRMQVDGE-QAKKT-GKAMPTFRATLTNMIRVEGFKSLYAG 100
            |:..:||: ...:|||  ||:|.|||:|:.|| ||:.| .:....|.|::..:.|.:|...|..|
Human     8 VDLVLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLWGLQKG 72

  Fly   101 FSAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKIYMALGCSFTAGCIAQAL----ANPFD 161
            .:|.:....:.|.:|...|.:..:..|.|..            |.:..||.:|.||    .:|..
Human    73 LAAGLLYQGLMNGVRFYCYSLACQAGLTQQP------------GGTVVAGAVAGALGAFVGSPAY 125

  Fly   162 IVKVRMQTEG-RRRQLGYDVRVNSMVQAFVDIYRRGGLPSMWKGVGPSCMRACLMTTGDVGSYDI 225
            ::|.::|.:. ....:|:.....:::.|...|:|:.||..:|:|||.:..|..:.:...:.::..
Human   126 LIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLATFAS 190

  Fly   226 SKRTFKRLLDLEEGLP-----LRFVSSMCAGLTASVLSTPADVIKSRMMNQPVDESGKNLYYKNS 285
            :|...::    ::.||     :.....|.:.:...|:.||.||:.:|:.|||||.:|:...|...
Human   191 AKAWVQK----QQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGL 251

  Fly   286 LDCVRKLVREEGVLTLYKGLMPTWFRLGP---FSVLFWLSVEQLRQWEGQS 333
            .||:.|:.|:||.|.|||||.|.:.||||   .|:|||   ::||:..|::
Human   252 TDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFW---DELRKLAGRA 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:395101	25/78 (32%)
		Mito_carr	137..232	CDD:395101	21/99 (21%)
		Mito_carr	237..329	CDD:395101	39/99 (39%)
SLC25A34	NP_997231.1	Mito_carr	2..91	CDD:395101	27/82 (33%)
		Solcar 1	4..97		28/88 (32%)
		Solcar 2	101..194		22/104 (21%)
		Mito_carr	<119..197	CDD:395101	15/77 (19%)
		Mito_carr	203..295	CDD:395101	37/94 (39%)
		Solcar 3	204..295		37/93 (40%)