DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4C and Ucp3

DIOPT Version :9

Sequence 1:	NP_608976.1	Gene:	Ucp4C / 33832	FlyBaseID:	FBgn0031757	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_037299.1	Gene:	Ucp3 / 25708	RGDID:	3933	Length:	308	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	106/322 - (32%)
Similarity:	163/322 - (50%)	Gaps:	52/322 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PPTNVADPLTARNLFQLYVNTFIGAN----LAESCVFPLDVAKTRMQVDGEQAKKTGKAMPTFR- 82
            |||.|.              .|:||.    .|:...||||.||.|:|:.||   ..|.....:|
  Rat    10 PPTTVV--------------KFLGAGTAACFADLLTFPLDTAKVRLQIQGE---NPGVQSVQYRG 57

  Fly    83 --ATLTNMIRVEGFKSLYAGFSAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKIYMALGC 145
              .|:..|:|.||.:|.|:|..|.:.|...|.|:|:.|||..:: |......:...:.|.:..||
  Rat    58 VLGTILTMVRTEGPRSPYSGLVAGLHRQMSFASIRIGLYDSVKQ-FYTPKGTDHSSVAIRILAGC 121

  Fly   146 SFTAGCIAQALANPFDIVKVRMQ------TEGRRRQLGYDVRVNSMVQAFVDIYRRGGLPSMWKG 204
              |.|.:|...|.|.|:||||.|      |.|.|:..|       .:.|:..|.|..|:..:|||
  Rat   122 --TTGAMAVTCAQPTDVVKVRFQAMIRLGTGGERKYRG-------TMDAYRTIAREEGVRGLWKG 177

  Fly   205 VGPSCMRACLMTTGDVGSYDISKRTFKRLLD---LEEGLPLRFVSSMCAGLTASVLSTPADVIKS 266
            ..|:..|..::...::.:|||.|   ::|||   ..:..|..|||:..||..|:|:::|.||:|:
  Rat   178 TWPNITRNAIVNCAEMVTYDIIK---EKLLDSHLFTDNFPCHFVSAFGAGFCATVVASPVDVVKT 239

  Fly   267 RMMNQPVDESGKNLYYKNSLDCVRKLVREEGVLTLYKGLMPTWFRLGPFSVLFWLSVEQLRQ 328
            |.||.|   .|:   |::.|.|:.::|.:||....|||.||::.|||.::|:.:::.|||::
  Rat   240 RYMNAP---PGR---YRSPLHCMLRMVAQEGPTAFYKGFMPSFLRLGSWNVMMFVTYEQLKR 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	29/77 (38%)
		Mito_carr	137..232	CDD:278578	31/100 (31%)
		Mito_carr	237..329	CDD:278578	35/92 (38%)
Ucp3	NP_037299.1	Mito_carr	10..107	CDD:278578	37/114 (32%)
		Solcar 1	11..102		35/108 (32%)
		PTZ00169	13..298	CDD:240302	103/319 (32%)
		Mito_carr	109..206	CDD:278578	33/108 (31%)
		Solcar 2	111..202		31/102 (30%)
		Mito_carr	209..299	CDD:278578	35/93 (38%)
		Solcar 3	211..296		35/91 (38%)
		Purine nucleotide binding. /evidence=ECO:0000250	275..297		7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810