DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ucp4C and SLC25A10

DIOPT Version :9

Sequence 1:	NP_608976.1	Gene:	Ucp4C / 33832	FlyBaseID:	FBgn0031757	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_001257882.1	Gene:	SLC25A10 / 1468	HGNCID:	10980	Length:	406	Species:	Homo sapiens

Alignment Length:	187	Identity:	48/187 - (25%)
Similarity:	78/187 - (41%)	Gaps:	43/187 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 AESCVFPLDVAKTRMQVDGE-QAKKTGKAMPTFRATLTNMIRVEGFKSLYAGFSAMVTRNFIFNS 113
            |..|..|||:.|..:|...| :.:.||.|:        .::|.:|..:||:|.||.:.|...::.
Human    20 AACCTHPLDLLKVHLQTQQEVKLRMTGMAL--------RVVRTDGILALYSGLSASLCRQMTYSL 76

  Fly   114 LRVVLYDVFR----------RPFLYQNERNEEVLKIYMALGCSFTAGCIAQALANPFDIVKVRMQ 168
            .|..:|:..|          .||      :|:||     ||.  .:|.....:..|.|:|.||||
Human    77 TRFAIYETVRDRVAKGSQGPLPF------HEKVL-----LGS--VSGLAGGFVGTPADLVNVRMQ 128

  Fly   169 T-----EGRRRQLGYDVRVNSMVQAFVDIYRRGGLPSMWKGVGPSCMRACLMTTGDV 220
            .     :|:||...:      .:.....:.|..||..::.|...:..|..|:|.|.:
Human   129 NDVKLPQGQRRNYAH------ALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQL 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	22/84 (26%)
		Mito_carr	137..232	CDD:278578	22/89 (25%)
		Mito_carr	237..329	CDD:278578
SLC25A10	NP_001257882.1	Mito_carr	13..93	CDD:278578	22/80 (28%)
SLC25A10	NP_001257882.1	Mito_carr	95..179	CDD:278578	26/102 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51917
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820