DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ucp4C and ucp1

DIOPT Version :9

Sequence 1:	NP_608976.1	Gene:	Ucp4C / 33832	FlyBaseID:	FBgn0031757	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_001107354.1	Gene:	ucp1 / 100135179	XenbaseID:	XB-GENE-963773	Length:	309	Species:	Xenopus tropicalis

Alignment Length:	293	Identity:	95/293 - (32%)
Similarity:	156/293 - (53%)	Gaps:	21/293 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 FIGANLAESCV-----FPLDVAKTRMQVDGE---QAKKTGKAMPTFRATLTNMIRVEGFKSLYAG 100
            ||.|..| :|:     ||||.||.|:|:.||   .....|........|::.:::.||.||||.|
Frog    17 FIAAGTA-ACIADLFTFPLDTAKVRLQIQGETTGSGAANGIRYKGVFGTISTIVKTEGPKSLYNG 80

  Fly   101 FSAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKIYMALGCSFTAGCIAQALANPFDIVKV 165
            ..|.:.|...|.|:|:.|||..:  ..|.|.:.:..:...:..||  |.|.:|..:|.|.|:|||
Frog    81 LVAGLQRQMSFASIRIGLYDTVK--LFYTNGKEKAGIGSRILAGC--TTGALAVTVAQPTDVVKV 141

  Fly   166 RMQTEGRRRQLGYDVRVNSMVQAFVDIYRRGGLPSMWKGVGPSCMRACLMTTGDVGSYDISKRTF 230
            |.|.:...:  |...|.|..:.|:..|.::.|:..:|||..|:..|..::...::.:||:.|...
Frog   142 RFQAQANLQ--GVKRRYNGTMDAYKTIAKKEGVRGLWKGTFPNVTRNAIVNCTELVTYDVIKENL 204

  Fly   231 KRLLDLEEGLPLRFVSSMCAGLTASVLSTPADVIKSRMMNQPVDESGKNLYYKNSLDCVRKLVRE 295
            .....:.:.||..|||:..||...:|:::|.||:|:|.||.|..:      ||::|:|...::.:
Frog   205 LHYKLMTDNLPCHFVSAFGAGFCTTVIASPVDVVKTRYMNSPPGQ------YKSALNCAWTMITK 263

  Fly   296 EGVLTLYKGLMPTWFRLGPFSVLFWLSVEQLRQ 328
            ||....|||.:|::.|||.::|:.::|.|||::
Frog   264 EGPTAFYKGFVPSFLRLGSWNVVMFVSYEQLKR 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:278578	29/82 (35%)
		Mito_carr	137..232	CDD:278578	27/94 (29%)
		Mito_carr	237..329	CDD:278578	34/92 (37%)
ucp1	NP_001107354.1	Mito_carr	10..110	CDD:278578	34/95 (36%)
		PTZ00169	14..299	CDD:240302	95/293 (32%)
		Mito_carr	111..208	CDD:278578	27/100 (27%)
		Mito_carr	211..302	CDD:278578	34/92 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910