DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9044 and AT1G48540

DIOPT Version :9

Sequence 1:	NP_001260114.1	Gene:	CG9044 / 33825	FlyBaseID:	FBgn0031752	Length:	1318	Species:	Drosophila melanogaster
Sequence 2:	NP_175287.2	Gene:	AT1G48540 / 841275	AraportID:	AT1G48540	Length:	1063	Species:	Arabidopsis thaliana

Alignment Length:	1124	Identity:	219/1124 - (19%)
Similarity:	411/1124 - (36%)	Gaps:	257/1124 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 TTLLKLTYFPSEHYFEGAIDIAKFRALRRLEVNK--INIGQVVGIQPLRGQLQHLICVKSLTSVD 149
            |:|..::..||.......:.:..|.:|:.||:.:  ::.....|:..||..|:.:||..|..::.
plant    87 TSLKVVSTLPSPARDPTPLSLFPFGSLKVLELRRCDLSTSPAKGLIELRHTLEKIICHNSTDALR 151

  Fly   150 DIITRCGGDNSNGFVWNELKTADFSYNSLRSVDTALEFAQHLQHLNLRHNKLTSVAAIKWLPHLK 214
            .:......:.:|...||:|.....:.|.|..:|.:|:.....:.|:|..||...|..::....||
plant   152 HVFASRIAEITNSPEWNKLAVISCACNRLVLMDESLQLLPAAESLDLSRNKFVKVDNLRRCTKLK 216

  Fly   215 TLDLSYNCLTHLPQFHMEACKRLQLLNISNNYVEELLDVAKLDALYNLDLSDNCLLEHSQLLPLS 279
            .|||.:|.|..:......:|..::|: :.||.:..|..:..|.:|..||:|.|.:...|:|..|.
plant   217 HLDLGFNHLRTVSYLSQVSCHLVKLV-LRNNALTTLRGIENLKSLQGLDVSYNIISNFSELEFLW 280

  Fly   280 ALMSLIVLNLQGNPLACNPKHRQATAQYLHKNSATVKFVLDFEPLTKAEKALTGSQKWRYISGLS 344
            :|..|..|.|:|||:.|...:|.....|:   :...:..||       .|.:...:.|:....::
plant   281 SLSQLKELWLEGNPVCCARWYRAHVFSYV---ALPDELKLD-------GKQIGTREFWKRQIIVA 335

  Fly   345 HRSPRSTSMSINSSSASINTSDGSQFSSFGSQRSVSIRGKNYTLEDNQSMDTSQSSKRISSCKIR 409
            ||.                 |:.:.:..:...|.          |||:....::..|:|  |::.
plant   336 HRQ-----------------SEPASYGFYSPARE----------EDNEEGSCNRKKKKI--CRLA 371

  Fly   410 TVDIE-ESSEINTDAASVSTPNPRSE---YEEEPD-------NSHLETKKKIETLRLTYGNEWLK 463
            ::..| ||:.:|:|..|.:..:...|   :.:|.|       ..||  ||:...|.|....||:
plant   372 SIHSEAESTYVNSDHESATCDHENKENMKFNQEADIFGLISKVEHL--KKERSVLWLREFKEWM- 433

  Fly   464 SGNAELMLGIETPQPTERERNESRQLFNEYLG---ELSGFTEAKNDSEHHNISSTP--TNNVLLA 523
                            :|...:...:..:..|   |...:|:.:..|.||. ..||  |:..|.|
plant   434 ----------------DRSTEDFADVCKDSQGINLEKKYYTKIREISRHHG-GGTPRYTSGSLRA 481

  Fly   524 STFDATITPIKSEAN--DTSGQTLYETCTEGEETNYESFGNNTTELSTEERPPDRHEELLRLYAS 586
            |...:....::...:  |......|....||.||.     ..|.::|:           :.|.::
plant   482 SRAKSYRKNLECNGSCVDHKAGMDYMKYVEGNETQ-----KITDDISS-----------ISLQST 530

  Fly   587 SSNAQDEDPVSDAESDEETYIVYHEQKPSEVLFLTISSNFIRE---------------------- 629
            ..|.:.::.|.|   :.|:..|    :|:::|..|::...:.|
plant   531 DRNQKHQECVHD---EMESLSV----EPNDLLPTTLAKEKLAENGNMSTLDITQHMTGSTYPGSP 588

  Fly   630 ----KDTLTERTKAKWSLKILESCERVRSNTLRI-NFDTMRKDKQERIYCVENTLCQELEKKLRD 689
                ||.|..|.      .::|...::.:::..: :.|:.....::..|..|:......|.:|.|
plant   589 PHYQKDVLYRRH------NLVEEILQLSADSYSVASSDSTSSCSEDDNYDSESEYSNHKEGRLTD 647

  Fly   690 ILSQRDLTEMNISIYRCVNCLTQFTIEQKSKRYKAKELRCPDCRSVYVAEVTELSSSLSKPSGEV 754
            :|   ::..:...|..|....|:|...|.......|.||..:...   ...|...|.|......|
plant   648 LL---NVNRLGKEILECTPKGTRFLGSQPENGSTIKTLRTDESMK---ETTTNFPSGLHNGKHGV 706

  Fly   755 AAEPKLSPAMIVEESPVEELAAAINKEESNSIVANCRLTTAKITPKLRSLTQATKSSANSLNGSS 819
            ....:|    :.:..|::.. .:..||||      | :|..:|:  |||....:.|      |..
plant   707 NQTDRL----VEKRKPIKRF-VSFQKEES------C-ITNGEIS--LRSDADISDS------GED 751

  Fly   820 SCSKITNSQSSFDSNQSVVGSSNTDRDMEFRANESDVDIISNPSQSSIEVLDPNYVQSASRKTSE 884
            .|.    |.:.:::..|.|.||:::|.::|...:..:.:             ..|..:....:|.
plant   752 VCI----SDNFWENTLSRVCSSSSNRSIKFLGTDRTLGV-------------EEYFSAKLSVSSS 799

  Fly   885 ERRISQLPHLETIHDEVAKSKSFIEREFGQLLAEQAQPTTPSTAAPLAPAKSAVPSHVPL--TES 947
            :.......:.:.|   :.|..::.:||...||:.|.:                  .:|.|  ..:
plant   800 QETCRTYMNCDLI---LQKGSTYKQREAVLLLSSQDK------------------LYVLLVGVTT 843

  Fly   948 SSSGSVTDSICTTYEQQATDAPQNLQNSLLTESSNSQVSGSDAESNSRLKSAEDASLLPFASVFQ 1012
            ...||....:|:...:...|....|....:                 ||:..||...:......:
plant   844 DYEGSTLSVLCSHEIKDLQDVSVGLGLQFV-----------------RLRFLEDVEYIFVTKCIK 891

  Fly  1013 STNLLMSSSKKLIESEATVFGTQPYKFNYSDFNDID---------HRLKLYFYQRKFKEDGEHFK 1068
            .|..|::.: ::.:|:||     .||.:.....:|.         ..|||..:|....    ||:
plant   892 KTTELLNIT-QVFDSQAT-----EYKCSLQSLENIQVDLFEKEICGGLKLSIFQYNVL----HFQ 946

  Fly  1069 --------WLAK-----GR---IYNEQTQSLGEGLVVMSNCKCYLME---AFAEPHDDVAKWLRQ 1114
                    ||.:     ||   |.:|....|.......|:...:|::   :.:|..:.:.:....
plant   947 STTRGEVSWLLRSLFVAGRRLFICSEDFTQLSSRTAYSSSAPYFLLDSCCSISEISEMIIETQGI 1011

  Fly  1115 VVSVAVNRLVAIDLLPWKL 1133
            |||:.:.....:||:.|||
plant  1012 VVSLKIKEKRTVDLVTWKL 1030

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9044	NP_001260114.1	LIP1	6..96	CDD:292526	2/8 (25%)
		LRR_RI	<102..302	CDD:238064	53/201 (26%)
		leucine-rich repeat	168..190	CDD:275380	5/21 (24%)
		LRR_4	189..229	CDD:289563	12/39 (31%)
		LRR_8	190..245	CDD:290566	14/54 (26%)
		leucine-rich repeat	191..212	CDD:275380	5/20 (25%)
		leucine-rich repeat	213..236	CDD:275380	8/22 (36%)
		leucine-rich repeat	237..258	CDD:275380	5/20 (25%)
		leucine-rich repeat	259..283	CDD:275380	9/23 (39%)
AT1G48540	NP_175287.2	leucine-rich repeat	113..149	CDD:275380	10/35 (29%)
		leucine-rich repeat	150..192	CDD:275380	8/41 (20%)
		LRR_RI	<189..297	CDD:238064	33/108 (31%)
		leucine-rich repeat	194..214	CDD:275378	5/19 (26%)
		leucine-rich repeat	215..237	CDD:275378	7/21 (33%)
		LRR_8	237..295	CDD:290566	19/58 (33%)
		leucine-rich repeat	238..259	CDD:275378	5/21 (24%)
		leucine-rich repeat	260..284	CDD:275378	9/23 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1859
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005584
OrthoInspector	1	1.000	-	-		otm3482
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15454
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910