DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9044 and AT3G17920

DIOPT Version :9

Sequence 1:	NP_001260114.1	Gene:	CG9044 / 33825	FlyBaseID:	FBgn0031752	Length:	1318	Species:	Drosophila melanogaster
Sequence 2:	NP_188419.2	Gene:	AT3G17920 / 819843	AraportID:	AT3G17920	Length:	1010	Species:	Arabidopsis thaliana

Alignment Length:	1336	Identity:	241/1336 - (18%)
Similarity:	441/1336 - (33%)	Gaps:	423/1336 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITELANLLRQNGDKILSSEFTLTLSGSLLRALNDSFTLIADTEI---GTGAGYLQPQ-----SFQ 62
            :..|...|.:..|.::.....|.|:.:.|..::.....:.:.|:   |....||:..     .|:
plant    10 LENLQRFLDEKADLLIDGTDVLKLNPAGLHYVHLRLESLRELELMLSGAPVDYLRAYVSDIGDFR 74

  Fly    63 VVKPINAKSSVFPDLQLVHDFVQKTTLLKLTYFPSEHYFEGAIDIAKFRALRRLEVN--KINIGQ 125
            .::.:.....:.|.|::|            :..||.......:.:..|..|:.||:.  .::...
plant    75 ALEQLRRILRLLPSLKVV------------SSLPSPARDPTPLSLLPFSKLKVLELRGCDLSTSS 127

  Fly   126 VVGIQPLRGQLQHLICVKSLTSVDDIITRCGGDNSNGFVWNELKTADFSYNSLRSVDTALEFAQH 190
            ..|:..||..|:.|||..|..::..:......:..:...||:|.....:.|.|..:|.:|:....
plant   128 AKGLLELRHTLEKLICHNSTDALRHVFASRIAEIKDSPQWNKLAFISCACNRLVLMDESLQLLPA 192

  Fly   191 LQHLNLRHNKLTSVAAIKWLPHLKTLDLSYNCLTHLPQFHMEACKRLQLLNISNNYVEELLDVAK 255
            ::.|:|..||...|..::....||.|||.:|.|..:......:|..::|: :.||.:..|..:..
plant   193 VESLDLSRNKFAKVDNLRRCNKLKHLDLGFNQLRKISHLSEVSCHLVKLV-LRNNALTTLRGIEN 256

  Fly   256 LDALYNLDLSDNCLLEHSQLLPLSALMSLIVLNLQGNPLACNPKHRQATAQYLHKNSATVKFVLD 320
            |.:|..||:|.|.:.:.|:|..|.:|..|..|.|:|||:.|...:|.....|::..:
plant   257 LKSLEGLDVSFNLISDFSELEFLGSLSFLTDLWLEGNPICCARWYRAHVLSYVYLPN-------- 313

  Fly   321 FEPLTKAEKALTGSQKWRYISGLSHRSPRSTSMSINSSSASINTSDGSQFSSFGSQRSVSIRGKN 385
              .|....|.:...:.|:....::.|..:..|....|.:......:|    ||..:::     |.
plant   314 --DLKLDGKHIGNREFWKRQVVVTRRKSQPASYGFYSPARDEADDEG----SFTRKKT-----KI 367

  Fly   386 YTLEDNQSMDTSQSSKRISSCKIRTVDIEESSEINTDAASVSTPNPRSEYEEEPDNSHLET---- 446
            |.|   .|:|:.                |||:.:|:|..|.|. .|.::.:||...|..|.
plant   368 YRL---ASIDSE----------------EESTYVNSDQESASC-EPETQSKEENIKSDHEADVFG 412

  Fly   447 --------KKKIETLRLTYGNEWLKSGNAELMLGIETPQPTERERNESRQLFNEYLGELSGFTEA 503
                    ||:...|.|....||:...:.:.:...:....|:.|:        :|      :.:.
plant   413 LICKVEQLKKERSVLWLREFKEWIDHPSEDFVDVSKNGSSTDSEQ--------KY------YMKN 463

  Fly   504 KNDSEHHNISSTPTNNVLLASTFDATITPIKSEANDTSGQTLYETCTEGEETNYESFGNNTTELS 568
            :|..:||                               |:|:  ..|.|...:::     .|:|:
plant   464 RNGPKHH-------------------------------GETM--RYTPGPLPSFQ-----ITDLN 490

  Fly   569 TEER------PPDRHEELLRLYASSSNAQDEDPVSDAESDEETYIVYHEQK--PSEVLFLTISSN 625
            .:.:      .||.:..:..|.||........|.|.....::   |.|.::  ..|:|.::..|.
plant   491 QKHQAFFLDGKPDENGNMSTLDASQDMTGSFSPSSPPHYQKD---VLHRRQNLVEEILQISADSY 552

  Fly   626 FIREKDTLTERTKAKWSLKILESCERVRSNTLRINFDTMRKDKQERIYCVENTLCQELEKKLRDI 690
            .:...|:               ||..      ..|:|:.:.:.:      ::||...|.....:.
plant   553 SVASSDS---------------SCSE------NENYDSEQSNPE------QDTLKDHLSGNRGED 590

  Fly   691 LSQRDLTEMNISIYRCVNCLTQFTIEQKSKRYKAKELRCPDCRSVYVAEVTELSSSLSKPSGEVA 755
            .|..|......||      :..:.||...|                 |:.|...|.|.|
plant   591 TSLLDSQPEKSSI------IKSWKIEDSFK-----------------AKTTNFLSGLHK------ 626

  Fly   756 AEPKLSPAMIVEESPVEELAAAIN-------KEESNSIVANCRLTTAKITPKLRSLTQATKSSAN 813
                            .|||:.:|       |::|            |..||.|:::...:.|.
plant   627 ----------------SELASGVNQIYRWFDKKQS------------KRKPKKRNVSPLEEYSF- 662

  Fly   814 SLNGSSSCSKITNSQSSFDSNQSVVGSSNTDRDMEFRANESDVDIISNPSQSSIEVLDPNYVQSA 878
                      |...::|                     :.||.|||.:.....|.    ::.|..
plant   663 ----------IKKGETS---------------------HRSDADIIDSCEDEYIS----DHFQEG 692

  Fly   879 SRKTSEERRISQLPHLETIHDEVAKSKSFIEREFGQLLAEQAQPTTPSTAAPLAPAKSAVPSHVP 943
            |..|....:               :|..|:|.|                       ||.
plant   693 SLTTGCNSK---------------RSTRFLETE-----------------------KSL------ 713

  Fly   944 LTESSSSGSVTDSICTTYEQQATDAPQNLQNSLLTESSNSQVS----GSDA--ESNSRLKSAEDA 1002
                ...|.:.:...||               .|::|||.:..    ..|.  :..|..|..|..
plant   714 ----EGMGGLVEEFFTT---------------TLSDSSNDETCRIYVSCDCILQQESTYKQREVV 759

  Fly  1003 SLLPFASVFQSTNLLMSSSKKLIESEATVFGTQPYKFNYSDFNDIDHRLKLYFYQRKFKEDGEHF 1067
            .||  :|..:...||:..|..|.||..::..:.    ...|..|:...|.|...:.:|:||.|
plant   760 LLL--SSQEKLYVLLVGVSTDLQESSLSLLCSH----TIGDIRDVSVGLGLQVVRLRFREDAE-- 816

  Fly  1068 KWLAKGRIYNEQTQSLGEGLVVMSNCKCYLMEAFAEPHDDVAKWLRQVVSVAVNRLVAIDLLPWK 1132
                    |...|.|:.:..|::                ::.|:|...|:.:...|.:::.:..:
plant   817 --------YIFMTASIEKTTVLL----------------NIIKFLDYQVTESKFSLKSLENVQVE 857

  Fly  1133 L-------GLSFTLKDWGGFVLLLHDMLRTESLLNYLQQIPLPEQCKLNHQPSVTLSHQWETIAS 1190
            |       ||..::..:    ::||....|...:::|.:             |:.::.....|.:
plant   858 LFEKEICSGLKLSIFQY----IVLHFQSSTFGEVSWLPR-------------SLFVAGGHLFICN 905

  Fly  1191 EPVKMCSLIPSCQWICDQEKS----SFEPSLLLITETHLYISGNGKFSWLSDKVQEKPIQPELSL 1251
            |..:..|.:|:     |...|    |.:.|..:.....:.:...|. |.||.||::|
plant   906 EDFRQLSFLPT-----DDASSSPYFSLDSSCSISDIFEMVVESRGS-SCLSLKVKQK-------- 956

  Fly  1252 NQPLSNLVDVERITDQKYAINFIDETQNRCEIWKLQ 1287
                    |....:.||..:|.:        .|||:
plant   957 --------DSTFQSSQKRTVNSV--------TWKLK 976

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9044	NP_001260114.1	LIP1	6..96	CDD:292526	14/97 (14%)
		LRR_RI	<102..302	CDD:238064	53/201 (26%)
		leucine-rich repeat	168..190	CDD:275380	5/21 (24%)
		LRR_4	189..229	CDD:289563	12/39 (31%)
		LRR_8	190..245	CDD:290566	14/54 (26%)
		leucine-rich repeat	191..212	CDD:275380	5/20 (25%)
		leucine-rich repeat	213..236	CDD:275380	8/22 (36%)
		leucine-rich repeat	237..258	CDD:275380	5/20 (25%)
		leucine-rich repeat	259..283	CDD:275380	9/23 (39%)
AT3G17920	NP_188419.2	leucine-rich repeat	51..78	CDD:275380	5/26 (19%)
		leucine-rich repeat	79..112	CDD:275380	6/44 (14%)
		leucine-rich repeat	113..136	CDD:275378	5/22 (23%)
		LRR_RI	<189..297	CDD:238064	33/108 (31%)
		leucine-rich repeat	193..214	CDD:275378	5/20 (25%)
		leucine-rich repeat	215..237	CDD:275378	7/21 (33%)
		LRR_8	237..295	CDD:290566	19/58 (33%)
		leucine-rich repeat	238..259	CDD:275378	5/21 (24%)
		leucine-rich repeat	260..284	CDD:275378	9/23 (39%)
		leucine-rich repeat	285..297	CDD:275378	6/11 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1859
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005584
OrthoInspector	1	1.000	-	-		otm3482
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15454
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910