DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9044 and CG11807

DIOPT Version :9

Sequence 1:	NP_001260114.1	Gene:	CG9044 / 33825	FlyBaseID:	FBgn0031752	Length:	1318	Species:	Drosophila melanogaster
Sequence 2:	NP_001260990.1	Gene:	CG11807 / 36683	FlyBaseID:	FBgn0033996	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	93/366 - (25%)
Similarity:	157/366 - (42%)	Gaps:	60/366 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITELANLLRQNGDKILSSEFTLTLSGSLLRALNDSFTLIADTEIGTGAGYLQPQSFQ-------- 62
            :.:||.|..::||.:|||:....||...:.|:::..:|.....:..|..|    .|.
  Fly   123 LQDLAKLFNESGDALLSSKKEYNLSALEVYAISERLSLPCPPSLDRGGKY----DFSHVLDFCTQ 183

  Fly    63 ----VVKPINAKSSVFPDLQLVHDFVQKTTLLKLTYFPSEHYFEGAIDIAKFRALRRLEVNKINI 123
                ||.|:...:|...|...|...:.::.::     |:...|    ::..||.|:.|:.:.::.
  Fly   184 LVALVVTPVKDNASYAQDYNTVDVPIDRSNII-----PNRLSF----NLNAFRNLKTLKFSALST 239

  Fly   124 GQVVGIQPLRGQLQHLICVKSLT--------SVDDIITRC-----------------GGDNSNGF 163
            ..:|.|:.|:..|| .|||.:.|        ..|::...|                 |...|||.
  Fly   240 ENIVDIELLKPTLQ-TICVHNTTIQNINQVLLCDNLHKHCDVPSLLPETILASPSGSGPSTSNGS 303

  Fly   164 ------VWNELKTADFSYNSLRSVDTALEFAQHLQHLNLRHNKLTSVAAIKWLPHLKTLDLSYNC 222
                  .|.|:...|.:.|.|..:|.::..|..|:.|.|..|::.:|..:..||.|:.|.||.|.
  Fly   304 ALVSADAWQEITELDLTGNLLTQIDGSVRTAPKLRRLILDQNRIRTVQNLAELPQLQLLSLSGNL 368

  Fly   223 LTHLPQFHMEACKRLQLLNISNNYVEELLDVAKLDALYNLDLSDNCLLEHSQLLPLSALMSLIVL 287
            :.....:|: ....|..|.::.|.::.|..:.||.:|.|||||.|.:.|..::..::.|..|..|
  Fly   369 IAECVDWHL-TMGNLVTLKLAQNKIKTLSGLRKLLSLVNLDLSSNQIEELDEVNHVANLPLLETL 432

  Fly   288 NLQGNPLACNPKHRQATAQYLHKNSATVKFVLDFEPLTKAE 328
            .|.|||||.:..:|.......|:.:|.:.  ||.||..:.|
  Fly   433 RLTGNPLAGSVDYRSRVLARFHERAAEIS--LDNEPGNQQE 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9044	NP_001260114.1	LIP1	6..96	CDD:292526	21/101 (21%)
		LRR_RI	<102..302	CDD:238064	62/230 (27%)
		leucine-rich repeat	168..190	CDD:275380	5/21 (24%)
		LRR_4	189..229	CDD:289563	12/39 (31%)
		LRR_8	190..245	CDD:290566	15/54 (28%)
		leucine-rich repeat	191..212	CDD:275380	6/20 (30%)
		leucine-rich repeat	213..236	CDD:275380	6/22 (27%)
		leucine-rich repeat	237..258	CDD:275380	6/20 (30%)
		leucine-rich repeat	259..283	CDD:275380	9/23 (39%)
CG11807	NP_001260990.1	PX_IRAS	8..126	CDD:132785	0/2 (0%)
		leucine-rich repeat	315..336	CDD:275380	5/20 (25%)
		LRR_8	335..414	CDD:290566	26/79 (33%)
		leucine-rich repeat	337..381	CDD:275380	13/44 (30%)
		LRR_4	381..422	CDD:289563	14/40 (35%)
		leucine-rich repeat	382..403	CDD:275380	6/20 (30%)
		leucine-rich repeat	404..428	CDD:275380	9/23 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452034
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1859
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR15454
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3315
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.870