Protein Alignment CG9044 and Stk11ip

DIOPT Version :10

• Sequence 1: NP_001260114.1
• Gene: CG9044 / 33825
• FlyBaseID: FBgn0031752
• Length: 1318
• Species: Drosophila melanogaster
• Sequence 2: XP_063123050.1
• Gene: Stk11ip / 301535
• RGDID: 1305046
• Length: 1124
• Species: Rattus norvegicus
• Alignment Length: 1471
• Identity: 316/1471 - (21%)
• Similarity: 493/1471 - (33%)
• Gaps: 535/1471 - (36%)

  Fly     6 ITELANLLRQNGDKILSSEFTLTLSGSLLRALNDSFTLIADTEIGTGAGYLQP----QSFQVVKP 66
            :.:||.|||::||.:||...||:|..:.|:.||..|.|           ||.|    |:..|..|
  Rat    10 VWKLAGLLRESGDAVLSGCSTLSLLTATLQQLNRVFEL-----------YLGPWGPGQTGFVALP 63

  Fly    67 IN-AKSSVFPDLQLVHDFVQKTTLLKLTYFPSEHYFEGAIDIAKFRALRRLEVNKINIGQVVGIQ 130
            .: |.|.|...||.:.|.:|||..|||.:.|... ..|.|.|..|::||:||:..:.|..:.|::
  Rat    64 SHPADSPVILQLQFLFDVLQKTLSLKLVHTPGVG-LPGPIKIFPFKSLRQLELRGVPIHSLCGLR 127

  Fly   131 PLRGQLQHLICVKSLTSVDDIITRCGGDNSNGFVWNELKTADFSYNSLRSVDTALEFAQHLQHLN 195
            .:..||:.|:|.:|:.:::::::.||||..:...|..|.:||||||:|.::|::|.....|:.||
  Rat   128 GIYSQLETLVCNRSIQALEELLSACGGDLCSALPWLALLSADFSYNALSNLDSSLRLLSALRFLN 192

  Fly   196 LRHNK----------------LTSVAAIKWLP---------HLKTLDLSYNCLTHLPQFHMEAC- 234
            |.||.                |..:..:..||         .|..||:|||.|..:|:......
  Rat   193 LSHNHIQDCKGFLMHTTRLGILDDLGQVSQLPASFTCKDLSELYHLDISYNHLRLVPRMGPSGAA 257

  Fly   235 ------KRLQLLNISNNY--------------------VEELLDVAKLDALYNLDLSDNCLLEHS 273
                  :..:|.::..|.                    :|:|.::..||..|||      |..|:
  Rat   258 LGTLILRANELRSLQGNTTPHPLTHNMPPQGLLSSAVGLEQLKNLRHLDVAYNL------LEGHT 316

  Fly   274 QLLPLSALMSLIVLNLQGNPLACNPKHRQATAQYL--HKNSATVKFVLDFEPLTKAEKALTGSQK 336
            :|.||..|..|..|.|:||||..:|.||..|||||  ....|...|:||.:.|:..:...|
  Rat   317 ELAPLWLLAELRKLYLEGNPLWFHPAHRATTAQYLSPRARDAAHGFLLDGKVLSLKDLQQT---- 377

  Fly   337 WRYISGLSHRSPRSTSMSINSSSASINTSDGSQFSSFGSQRSVSIRGKNYTLEDNQSMDTSQSSK 401
                |..|...|.:..:|....|.: .||.|.:.|.              :|.....:..:...|
  Rat   378 ----SESSRLGPMTQPLSWPVGSTT-ETSGGPELSD--------------SLSSGGIVAQAPLRK 423

  Fly   402 RISSCKIRTVDIEESSEINTDAASVSTPNPRSEYEEEPDNSHLETKKKIETLRLTYGNEWLKSGN 466
            ..|..::|...|.|.|:.:.:..::. |:|...:.::    |.|. :.:.:.|..:|.:||
  Rat   424 VKSRVRVRRASISEPSDTDPELRTLD-PSPAGWFVQQ----HREL-ELLASFRERFGCDWL---- 478

  Fly   467 AELMLGIETPQPTERERNESRQLFNEYLGELSGFTEAKNDSEHHNISSTPTNNVLLASTFDATIT 531
                                     :|...|            ..:.|.|             :.
  Rat   479 -------------------------QYRSHL------------ETMGSPP-------------LA 493

  Fly   532 PIKSEANDT---SGQTLYETCTE----GEETNYESFGNNTTELSTEERPPDRHEELLRLYASSSN 589
            .||:.|..|   ..|:| ||...    ||:|. || ....:|...||..|  |||     .....
  Rat   494 TIKTPALGTPPLDAQSL-ETARSPPAIGEDTK-ES-PEKVSEEGREELEP--HEE-----EREEQ 548

  Fly   590 AQDEDPVSDAESDEETYIVYHEQKPSEV---------------------LFLTISSNFIREKDTL 633
            .::|....|...:||     .|||..|.                     .||.::|..:.|....
  Rat   549 EREEGSREDLGEEEE-----QEQKAVEAELCRPMLVCPLQGTEGVQGRECFLRVTSAHLFEVGLQ 608

  Fly   634 TERTKAKWSLKILESCERVRSNT-------------------LRINFDTMRKDKQERIYCVENTL 679
            ..:|..:..|:.|.|.| ::|.|                   |.:.|..:..|:|.|.|.|   |
  Rat   609 AAQTLERLELQSLVSAE-LQSETESQREPGSEGSGPPSGAPVLVLRFSYICPDRQLRCYAV---L 669

  Fly   680 CQELEKKLRDILSQRDLTEMNISIYRCVNCLTQFTIEQKSKRYKAKE--------LRCPDCRSVY 736
            ..|..:.::::|:                .||.||..:..:..:||:        |||
  Rat   670 EPEAHEAIQELLA----------------VLTPFTSVKDQQPGEAKDPQGPRFQCLRC------- 711

  Fly   737 VAEVTELSSSLSKPSGEVAAEPKL--------SPAMIVEESPVEELAAAINKEESNSIVANCRLT 793
                    |...||.     ||:|        .|.....||||              :..||
  Rat   712 --------SCEFKPQ-----EPRLGLESDDGWKPLFQNTESPV--------------VCPNC--- 746

  Fly   794 TAKITPKLRSLTQATKSSANSLNGSSSCSKITNSQSSFDSNQSVVGS-SNTDRDMEFRANESDVD 857
                                   ||.....:           :|.|. .|.:|:.|.::::|..|
  Rat   747 -----------------------GSDHVVLL-----------AVSGEVPNRERNQEEQSSDSACD 777

  Fly   858 IISNPSQSSIEVLDPNYVQSASRKTSEERRISQLPHLETIHDEVAKSKSFIEREFGQLLAEQAQP 922
            :..:
  Rat   778 LADH------------------------------------------------------------- 781

  Fly   923 TTPSTAAPLAPAKSAVPSHVPLTESSSSGSVTDSICTTYEQQATDAPQNLQNSLLTESSNSQVSG 987
                :..|      :||..:|...|.|.|      |:::         ||..:|
  Rat   782 ----SGCP------SVPDGIPPQASISHG------CSSW---------NLSPTL----------- 810

  Fly   988 SDAESNSRLKSAEDASLLPFASVFQSTNLLMSSSKKLIESEATVFGTQPYKFNYSDFNDIDHRLK 1052
                                                                .::.|..:||||:
  Rat   811 ----------------------------------------------------GHTGFRSVDHRLR 823

  Fly  1053 LYFYQRKFKEDGEHFKWLAKGRIY--NEQTQSLGEGLVVMSNCKCYLMEAFAEPHDDVAKWLRQV 1115
            |:.....|.:..|.|:...|..:.  ....:||  .|||:|:...||::.........|.||...
  Rat   824 LFLDVEVFSDSEEEFQCCTKVPVVLAGHTRESL--CLVVVSDRMLYLLKVTGPICGPPASWLEPT 886

  Fly  1116 VSVAVNRLVAIDL--------LPWKLGLSFTLKDWGGFVLLLHDMLR----TESLLNYLQQIPLP 1168
            :::.:..|..::|        |.|..|.       |..|||..|..:    .|.|...||.:|..
  Rat   887 LAIPLQDLSGMELGLAGQSLRLEWAAGT-------GHCVLLPRDARQCRAFLEELTGVLQSLPRT 944

  Fly  1169 EQ-CKLNHQPSVTLSHQ-W-----ETIASEPVKMCSLIPSCQWICDQEKSSFEPSLLLITETHLY 1226
            :: |....:.:||..|: |     :|.|..|..........:...:...||..|..||:|.:.||
  Rat   945 QRNCISATEETVTPQHRLWPLLGKDTSAETPQFFYLRAFLAEGKAESAGSSTCPVSLLLTLSTLY 1009

  Fly  1227 I---------------SGNGKFSWLSDKVQEKPIQPELSL----NQPLSNLVDVE--RITDQKYA 1270
            :               .|:|:.|     .|..|..|..||    .||||:|..|:  |.:.....
  Rat  1010 LLDEDPVRSHAESPLPVGSGEAS-----EQPAPQGPGPSLQVREQQPLSSLSSVQLYRTSPLDLR 1069

  Fly  1271 INFIDETQNRCEIWKLQFETHANAACCLNVIGKGWEQLFGV 1311
            :.|.||.......|.|:..........|..|.:.||:||.:
  Rat  1070 LIFYDEVSRLESFWALRVVCGEQLTDLLAWIREPWEELFSI 1110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9044	NP_001260114.1	LIP1	1..96	CDD:464931	35/94 (37%)
		leucine-rich repeat	168..190	CDD:275380	10/21 (48%)
		PPP1R42	176..302	CDD:455733	45/177 (25%)
		leucine-rich repeat	191..212	CDD:275380	9/45 (20%)
		leucine-rich repeat	213..236	CDD:275380	8/29 (28%)
		leucine-rich repeat	237..258	CDD:275380	5/40 (13%)
		leucine-rich repeat	259..283	CDD:275380	9/23 (39%)
Stk11ip	XP_063123050.1	None