DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gpdh1 and GPDHp

DIOPT Version :9

Sequence 1:	NP_001260112.1	Gene:	Gpdh1 / 33824	FlyBaseID:	FBgn0001128	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_198877.1	Gene:	GPDHp / 834060	AraportID:	AT5G40610	Length:	400	Species:	Arabidopsis thaliana

Alignment Length:	347	Identity:	182/347 - (52%)
Similarity:	241/347 - (69%)	Gaps:	7/347 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KVNVCIVGSGNWGSAIAKIVGANAAALPEFEERVTMFVYEELI-DGKKLTEIINETHENVKYLKG 67
            |..|.:||||||||..||::.:||..||.|.:.|.|:|:||:: :|:||.::||:|:||||||.|
plant    54 KSKVTVVGSGNWGSVAAKLIASNALKLPSFHDEVRMWVFEEVLPNGEKLNDVINKTNENVKYLPG 118

  Fly    68 HKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFD-KAEGGGI 131
            .||..||||.|||..|.|:|::|:||.||||:...||:|.|||..:..||||:||.: |.||.
plant   119 IKLGRNVVADPDLENAVKDANMLVFVTPHQFMDGICKKLDGKITGDVEAISLVKGMEVKKEGP-- 181

  Fly   132 DLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCT-DKKYGKVLRDLFQANHFRVVVVDD 195
            .:||.:|::.|.|.|.||||||:|||:|...|.|.|:|.. .::.......||...:|.|..|.|
plant   182 CMISSLISKQLGINCCVLMGANIANEIAVEKFSEATVGYRGSREIADTWVQLFSTPYFMVTPVHD 246

  Fly   196 ADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGSKLSTFFESCGVA 260
            .:.||:||.|||:||..|||||||::|:|||||::|:||.||.....:.:|..|.||||||||||
plant   247 VEGVELCGTLKNVVAIAAGFVDGLEMGNNTKAAIMRIGLREMKALSKLLFPSVKDSTFFESCGVA 311

  Fly   261 DLITTCYGGRNRRVSEAFVTS-GK-TIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLF 323
            |:||||.|||||||:|||..| || :.:|||.|||.||||||..||.||..:||:.|..:.||||
plant   312 DVITTCLGGRNRRVAEAFAKSRGKRSFDELEAEMLQGQKLQGVSTAREVYEVLKHCGWLEMFPLF 376

  Fly   324 TAIHKICTNQLKPNDLIDCIRN 345
            :.:|:|||.:|:|..::....|
plant   377 STVHQICTGRLQPEAIVQYREN 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gpdh1	NP_001260112.1	glycerol3P_DH	6..343	CDD:274551	180/341 (53%)
GPDHp	NP_198877.1	glycerol3P_DH	56..395	CDD:274551	180/340 (53%)
		NAD_Gly3P_dh_N	56..220	CDD:279543	87/165 (53%)
		NAD_Gly3P_dh_C	247..390	CDD:284817	85/142 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	173	1.000	Domainoid score	I1136
eggNOG	1	0.900	-	-		E1_COG0240
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	339	1.000	Inparanoid score	I649
OMA	1	1.010	-	-		QHG56883
OrthoDB	1	1.010	-	-		D476066at2759
OrthoFinder	1	1.000	-	-		FOG0000846
OrthoInspector	1	1.000	-	-		otm3403
orthoMCL	1	0.900	-	-		OOG6_100385
Panther	1	1.100	-	-	LDO	PTHR11728
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X660
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840