DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gpdh1 and Gpd1l

DIOPT Version :9

Sequence 1:	NP_001260112.1	Gene:	Gpdh1 / 33824	FlyBaseID:	FBgn0001128	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001178814.1	Gene:	Gpd1l / 363159	RGDID:	1560123	Length:	351	Species:	Rattus norvegicus

Alignment Length:	351	Identity:	213/351 - (60%)
Similarity:	265/351 - (75%)	Gaps:	4/351 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ADKVNVCIVGSGNWGSAIAKIVGANAAALPEFEERVTMFVYEELIDGKKLTEIINETHENVKYLK 66
            |..:.||||||||||||:|||:|:|...|.:|...|.|:|:||.::|:|||:|||..|||||||.
  Rat     3 AAPLKVCIVGSGNWGSAVAKIIGSNVKNLQKFSSTVKMWVFEETVNGRKLTDIINNDHENVKYLP 67

  Fly    67 GHKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEG-GG 130
            |||||.||||||:|.||.::||:|:||:|||||...|.::.|::...|:.|:||||.|  || .|
  Rat    68 GHKLPENVVAVPNLGEAVQDADLLVFVIPHQFIHKICDEITGRVPKKAVGITLIKGID--EGPDG 130

  Fly   131 IDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYGKVLRDLFQANHFRVVVVDD 195
            :.|||.||...:.|..:||||||:|:|||...|||||||....:.|.:.::|.|..:||:.||||
  Rat   131 LKLISDIIREKMGIDISVLMGANIASEVAAEKFCETTIGSKVLQNGLLFKELLQTPNFRITVVDD 195

  Fly   196 ADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGS-KLSTFFESCGV 259
            ||.||:|||||||||.||||.|||..|||||||||||||||||.|..:|..|. ..:||.|||||
  Rat   196 ADTVELCGALKNIVAVGAGFCDGLCCGDNTKAAVIRLGLMEMIAFAKIFCKGQVSTATFLESCGV 260

  Fly   260 ADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLFT 324
            |||||||||||||:|:|||..:||||||||||:|||||||||.|:.||..:||.|||.|||||||
  Rat   261 ADLITTCYGGRNRKVAEAFARTGKTIEELEKELLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFT 325

  Fly   325 AIHKICTNQLKPNDLIDCIRNHPEHM 350
            |:::||........::.|:::||||:
  Rat   326 AVYQICYEGRPVTQMLSCLQSHPEHI 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gpdh1	NP_001260112.1	glycerol3P_DH	6..343	CDD:274551	207/338 (61%)
Gpd1l	NP_001178814.1	glycerol3P_DH	7..344	CDD:274551	207/338 (61%)
		NAD_Gly3P_dh_N	7..171	CDD:279543	97/165 (59%)
		NAD_Gly3P_dh_C	198..337	CDD:284817	99/138 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354416
Domainoid	1	1.000	227	1.000	Domainoid score	I2417
eggNOG	1	0.900	-	-		E1_COG0240
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	459	1.000	Inparanoid score	I1516
OMA	1	1.010	-	-		QHG56883
OrthoDB	1	1.010	-	-		D346303at33208
OrthoFinder	1	1.000	-	-		FOG0000846
OrthoInspector	1	1.000	-	-		otm45710
orthoMCL	1	0.900	-	-		OOG6_100385
Panther	1	1.100	-	-	O	PTHR11728
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X660
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770