Protein Alignment Gpdh1 and GPD1

DIOPT Version :10

• Sequence 1: NP_476565.1
• Gene: Gpdh1 / 33824
• FlyBaseID: FBgn0001128
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_005267.2
• Gene: GPD1 / 2819
• HGNCID: 4455
• Length: 349
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 234/352 - (66%)
• Similarity: 275/352 - (78%)
• Gaps: 5/352 - (1%)

  Fly     1 MADKVNVCIVGSGNWGSAIAKIVGANAAALPEFEERVTMFVYEELIDGKKLTEIINETHENVKYL 65
            ||.| .||||||||||||||||||.|||.|.:|:.||||:|:||.|.|||||||||..|||||||
Human     1 MASK-KVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHENVKYL 64

  Fly    66 KGHKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEG-G 129
            .|||||||||||||:|:||::|||||||||||||...|.||.|.:|.||..||||||.|  || .
Human    65 PGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKGVD--EGPN 127

  Fly   130 GIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYGKVLRDLFQANHFRVVVVD 194
            |:.|||.:|...|.||.:||||||:|:|||:..||||||||.|...|::|::|.|..:||:.||.
Human   128 GLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKELMQTPNFRITVVQ 192

  Fly   195 DADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGSKLS-TFFESCG 258
            :.|.||:||||||:||.||||.|||..|||||||||||||||||.|..:|..|...| ||.||||
Human   193 EVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGPVSSATFLESCG 257

  Fly   259 VADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLF 323
            ||||||||||||||:|:|||..:||:||:||||:|||||||||.||.|:..:|::|||.||||||
Human   258 VADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPETARELYSILQHKGLVDKFPLF 322

  Fly   324 TAIHKICTNQLKPNDLIDCIRNHPEHM 350
            .|::|:|.......:.|.|::||||||
Human   323 MAVYKVCYEGQPVGEFIHCLQNHPEHM 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpdh1	NP_476565.1	glycerol3P_DH	6..343	CDD:274551	224/338 (66%)
GPD1	NP_005267.2	glycerol3P_DH	5..342	CDD:274551	224/338 (66%)