Protein Alignment dsf and NR2C2

DIOPT Version :9

• Sequence 1: NP_001260109.1
• Gene: dsf / 33823
• FlyBaseID: FBgn0015381
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_011532360.1
• Gene: NR2C2 / 7182
• HGNCID: 7972
• Length: 648
• Species: Homo sapiens
• Alignment Length: 705
• Identity: 161/705 - (22%)
• Similarity: 247/705 - (35%)
• Gaps: 264/705 - (37%)

  Fly    13 CKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLAKC 77
            |.||||::||:|||..||:||.||||||:.:|..|:|::..|    |.::|.|||:|:.|||.||
Human   169 CVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSNQD----CIINKHHRNRCQFCRLKKC 229

  Fly    78 FQSAMNKDAVQHERGP-----RKPKLHPQLHHHHHHAAAAAAAAHHAAAAHHHHHHHHHAHAAAA 137
            .:..|..::||.||.|     .||
Human   230 LEMGMKMESVQSERKPFDVQREKP----------------------------------------- 253

  Fly   138 HHAAVAAAAASGLHHHHHAMPVSLVTNVSASFNYTQHI----STHPPAPAAPPSGFHLTASGAQQ 198
                                     :|.:||   |:.|    ....|..|.|.  |.....||:|
Human   254 -------------------------SNCAAS---TEKIYIRKDLRSPLIATPT--FVADKDGARQ 288

  Fly   199 GPAPPAGHLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSGPGSTLPFPSHLL 263
                               |....||....:..|   ::...|                  :.||
Human   289 -------------------TGLLDPGMLVNIQQP---LIREDG------------------TVLL 313

  Fly   264 HHNLIAEAASKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNNHNYSSPSPSNSIQSISSIGSR 328
            ..:..||.:....|..|..|.::.:            .|.|.||.:.|...|.:  ||.|.|...
Human   314 ATDSKAETSQGALGTLANVVTSLAN------------LSESLNNGDTSEIQPED--QSASEITRA 364

  Fly   329 SGGGEEGLSLGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSPQHRQMSRHSLSEATT 393
            .....:.|:             |...|:||.|:.|       :.||.|.      |.|.:|...:
Human   365 FDTLAKALN-------------TTDSSSSPSLADG-------IDTSGGG------SIHVISRDQS 403

  Fly   394 PP-----------SHASLMICASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSGVGST 447
            .|           :|.:..:                              |.|:|.|....|...
Human   404 TPIIEVEGPLLSDTHVTFKL------------------------------TMPSPMPEYLNVHYI 438

  Fly   448 CNTASSSSGFLELLLSPDKCQELIQYQVQHNTLLFPQQLLDSRLLSWEMLQETTARLLFMAVRWV 512
            |.:||                                                  ||||:::.|.
Human   439 CESAS--------------------------------------------------RLLFLSMHWA 453

  Fly   513 KCLMPFQTLSKNDQHLLLQESWKELFLLNLAQWTIPLDLTPILESPL--IRERVLQDEATQTEMK 575
            :.:..||.|.::....|::..|.|||.|.|||....:.|:.||.:.:  ::..:.:|:.:...:|
Human   454 RSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQEDKLSGDRIK 518

  Fly   576 TIQEILCRFRQ-------ITPDGSEVGCMKAIALFAPETAGLCDVQPVEMLQDQAQCILSDHVRL 633
            .:.|.:.:.::       :..||.|...:|||.||:|:..||.....:|..|::||..|.|:|:.
Human   519 QVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTSTSQIEKFQEKAQMELQDYVQK 583

  Fly   634 RYPRQATRFGRLLLLLPSLRTIRAATIEALFFKETIGNVPIARLLRDMYTMEPAQ 688
            .|.....|..|:|:.||:||.:.:...|.|||...||||.|..::..:..||.|:
Human   584 TYSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIPYILKMETAE 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	43/89 (48%)
		NR_LBD_Tlx_PNR_like	467..671	CDD:132748	54/212 (25%)
NR2C2	XP_011532360.1	NR_DBD_TR2_like	164..250	CDD:143525	41/84 (49%)
		NR_LBD_TR2_like	413..634	CDD:132750	67/300 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7185
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.860