Protein Alignment dsf and NR2F1

DIOPT Version :9

• Sequence 1: NP_001260109.1
• Gene: dsf / 33823
• FlyBaseID: FBgn0015381
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_005645.1
• Gene: NR2F1 / 7025
• HGNCID: 7975
• Length: 423
• Species: Homo sapiens
• Alignment Length: 696
• Identity: 153/696 - (21%)
• Similarity: 211/696 - (30%)
• Gaps: 370/696 - (53%)

  Fly     2 GTAGDR----------LLDIPCKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLK 56
            |||||:          ...|.|.||||:|||||||.::|:||..|||||:.||..|||:|..:
Human    65 GTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRN-- 127

  Fly    57 GRCPVDKTHRNQCRACRLAKCFQSAMNKDAVQHERGPRKPKLHPQLHHHHHHAAAAAAAAHHAAA 121
              ||:|:.|||||:.|||.||.:..|.::|||..|.|
Human   128 --CPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMP---------------------------- 162

  Fly   122 AHHHHHHHHHAHAAAAHHAAVAAAAASGLHHHHHAMPVSLVTNVSASFNYTQHISTHPPAPAAPP 186
                                                                             
Human   163 ----------------------------------------------------------------- 162

  Fly   187 SGFHLTASGAQQGPAPPAGHLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSG 251
                         |..|                                   |||
Human   163 -------------PTQP-----------------------------------NPG---------- 169

  Fly   252 PGSTLPFPSHLLHHNLIAEAASKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNNHNYSSPSPS 316
                                                        ..|.|:....|.|.|.|
Human   170 --------------------------------------------QYALTNGDPLNGHCYLS---- 186

  Fly   317 NSIQSISSIGSRSGGGEEGLSLGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSPQHR 381
                                                                             
Human   187 ----------------------------------------------------------------- 186

  Fly   382 QMSRHSLSEATTPPSHASLMICASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSGVGS 446
                          .:.||::.|.                                |.|.|..||
Human   187 --------------GYISLLLRAE--------------------------------PYPTSRYGS 205

  Fly   447 TCNTASSSSGFLELLLSPDKCQELIQYQVQHNTLLFPQQLLDSRLLSWEMLQETTARLLFMAVRW 511
            .|             :.|                        :.::..|.:.|..|||||.||.|
Human   206 QC-------------MQP------------------------NNIMGIENICELAARLLFSAVEW 233

  Fly   512 VKCLMPFQTLSKNDQHLLLQESWKELFLLNLAQWTIPLDLTPIL------ESPLIRERVLQDEAT 570
            .:.:..|..|...||..||:.:|.|||:||.||.::||.:.|:|      .||:..:||:   |.
Human   234 ARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVV---AF 295

  Fly   571 QTEMKTIQEILCRFRQITPDGSEVGCMKAIALFAPETAGLCDVQPVEMLQDQAQCILSDHVRLRY 635
            ...::..||.:.:.:.:..|.:|..|:|||.||..:..||.|...:|.||:::||.|.::||.:|
Human   296 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQY 360

  Fly   636 PRQATRFGRLLLLLPSLRTIRAATIEALFFKETIGNVPIARLLRDM 681
            |.|.:|||:|||.||||||:.::.||.|||...:|..||..|:|||
Human   361 PNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDM 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	48/102 (47%)
		NR_LBD_Tlx_PNR_like	467..671	CDD:132748	74/209 (35%)
NR2F1	NP_005645.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		5/15 (33%)
		NR_DBD_COUP_TF	86..158	CDD:143516	42/75 (56%)
		NR_LBD_COUP-TF	184..419	CDD:132746	93/378 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910