Protein Alignment dsf and RORB

DIOPT Version :9

• Sequence 1: NP_001260109.1
• Gene: dsf / 33823
• FlyBaseID: FBgn0015381
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001351952.1
• Gene: RORB / 6096
• HGNCID: 10259
• Length: 470
• Species: Homo sapiens
• Alignment Length: 687
• Identity: 126/687 - (18%)
• Similarity: 210/687 - (30%)
• Gaps: 249/687 - (36%)

  Fly    11 IPCKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLA 75
            ||||:|||:|||.|||:.:|:||.|||:||...|..|:|..    :..|.:|:|:||:|:.|||.
Human    19 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPR----QRNCLIDRTNRNRCQHCRLQ 79

  Fly    76 KCFQSAMNKDAVQHERGPRKPK--LHPQLHHHHHHAAAAAAAAHHAAAAHHHHHHHHHAHAAAAH 138
            ||....|::|||:..|..:|.:  |:.::..|..
Human    80 KCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQ------------------------------- 113

  Fly   139 HAAVAAAAASGLHHHHHAMPVSLVTNVSASFNYTQHISTHPPAPAAPPSGFHLTASGAQQGPAPP 203
                                                               .|.....||.
Human   114 ---------------------------------------------------RLQEQRQQQS---- 123

  Fly   204 AGHLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSGPGSTLPFPSHLLHHNLI 268
                                |...||...:...:||...|.:
Human   124 --------------------GEAEALARVYSSSISNGLSNLN----------------------- 145

  Fly   269 AEAASKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNN-HNYSSPSPSNSIQSISSIGSRSGGG 332
                               :.||..||:......|.|.. :|..|..||         ..:||..
Human   146 -------------------NETSGTYANGHVIDLPKSEGYYNVDSGQPS---------PDQSGLD 182

  Fly   333 EEGLSLGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSPQHRQMSRHSLSEATTPPSH 397
            ..|:....:.|..:: |..|:.......:.|.::|..|:|......|:...|.....:.|....|
Human   183 MTGIKQIKQEPIYDL-TSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELH 246

  Fly   398 ASLMICASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSGVGSTCNTASSSSGFLELLL 462
                                                                         :|..
Human   247 -------------------------------------------------------------QLAW 250

  Fly   463 SPDKCQELIQYQVQHNTLLFPQQLLDSRLLSWEMLQETTARLLFMAVRWVKCLMPFQTLSKNDQH 527
            .....:|:..||.:            ||...|:.........:...|.:.|.:..|..|.:|||.
Human   251 QTHTYEEIKAYQSK------------SREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQI 303

  Fly   528 LLLQESWKELFLLNLAQWTIPLDLTPILESP---LIRERVLQDEATQTEMKTIQEILCRFRQITP 589
            |||:....|:.|:.:.:...||:.|.:.|..   :...:.|..:....|.....:.||.. |:|.
Human   304 LLLKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSL-QLTE 367

  Fly   590 DGSEVGCMKAIALFAPETAGLCDVQPVEMLQDQAQCILSDHVRLRYPRQATRFGRLLLLLPSLRT 654
            :  |:....:..|.:|:.|.|.:.:.|:.||::....| .||..:.........:|:..:|::..
Human   368 E--EIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFAL-QHVIQKNHLDDETLAKLIAKIPTITA 429

  Fly   655 IRAATIEAL-FFKET---IGNVPIARLLRDMYTMEPA 687
            :.....|.| .||::   |.|.....|.::::..:.|
Human   430 VCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPDCA 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	41/88 (47%)
		NR_LBD_Tlx_PNR_like	467..671	CDD:132748	46/210 (22%)
RORB	NP_001351952.1	NR_DBD_ROR	14..108	CDD:143526	42/92 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..127		6/128 (5%)
		NR_LBD_ROR_like	221..461	CDD:132737	54/316 (17%)
		AF-2	456..461		1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910