Protein Alignment dsf and NR4A2

DIOPT Version :9

• Sequence 1: NP_001260109.1
• Gene: dsf / 33823
• FlyBaseID: FBgn0015381
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_005246678.1
• Gene: NR4A2 / 4929
• HGNCID: 7981
• Length: 609
• Species: Homo sapiens
• Alignment Length: 691
• Identity: 114/691 - (16%)
• Similarity: 175/691 - (25%)
• Gaps: 375/691 - (54%)

  Fly    13 CKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLAKC 77
            |.||||.::.:|||:.:|:||.|||||::.:|..|.|.|..:    |||||..||:|:.||..||
Human   274 CAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKN----CPVDKRRRNRCQYCRFQKC 334

  Fly    78 FQSAMNK-----DAVQHERG--PRKPKLHPQLHHHHHHAAAAAAAAHHAAAAHHHHHHHHHAHAA 135
            ....|.|     |:::..||  |.|||
Human   335 LAVGMVKEVVRTDSLKGRRGRLPSKPK-------------------------------------- 361

  Fly   136 AAHHAAVAAAAASGLHHHHHAMPVSLVTNVSASFNYTQHISTHPPAPAAPPSGFHLTASGAQQGP 200
                                                    |...|:|.:||
Human   362 ----------------------------------------SPQEPSPPSPP-------------- 372

  Fly   201 APPAGHLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSGPGSTLPFPSHLLHH 265
                                                                             
Human   373 ----------------------------------------------------------------- 372

  Fly   266 NLIAEAASKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNNHNYSSPSPSNSIQSISSIGSRSG 330
                                                                             
Human   373 ----------------------------------------------------------------- 372

  Fly   331 GGEEGLSLGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSPQHRQMSRHSLSEATTPP 395
                 :||.|...|.:|::
Human   373 -----VSLISALVRAHVDS---------------------------------------------- 386

  Fly   396 SHASLMICASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSGVGSTCNTASSSSGFLEL 460
                                                                 |.|.:|..:...
Human   387 -----------------------------------------------------NPAMTSLDYSRF 398

  Fly   461 LLSPDKCQELIQYQVQHNTLLFPQQLLDSRLLSWEMLQETTARLLFMAVRWVKCLMPFQTLSKND 525
            ..:||       ||:..:.....||..|....|.|:::           .|.:.:..|..|.|.|
Human   399 QANPD-------YQMSGDDTQHIQQFYDLLTGSMEIIR-----------GWAEKIPGFADLPKAD 445

  Fly   526 QHLLLQESWKELFLLNLAQWTIPLDLTPILESPLIRERVLQDEATQTEMKTIQEILCRFRQITPD 590
            |.||.:.::.|||:|.||..:.|::...|..:.::..|:.........:.:|.|.....:.:..|
Human   446 QDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNID 510

  Fly   591 GSEVGCMKAIALFAPETAGLCDVQPVEMLQDQAQCILSDHVR-----LRYPRQATRFGRLLLLLP 650
            .|...|:.|:|: ..|..||.:.:.||.||::....|.|||.     |..|..   ..:||..||
Human   511 ISAFSCIAALAM-VTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNY---LSKLLGKLP 571

  Fly   651 SLRTIRAATIEALFFKETIGNVPIARLLRDMYTMEPAQVDK 691
            .|||:....::.:|:.:....||           .||.:||
Human   572 ELRTLCTQGLQRIFYLKLEDLVP-----------PPAIIDK 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	40/91 (44%)
		NR_LBD_Tlx_PNR_like	467..671	CDD:132748	52/208 (25%)
NR4A2	XP_005246678.1	NR_DBD_NGFI-B	272..346	CDD:143527	34/75 (45%)
		NR_LBD_Nurr1	372..609	CDD:132756	69/511 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910