DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dsf and knrl

DIOPT Version :9

Sequence 1:	NP_001260109.1	Gene:	dsf / 33823	FlyBaseID:	FBgn0015381	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_001303368.1	Gene:	knrl / 40285	FlyBaseID:	FBgn0001323	Length:	647	Species:	Drosophila melanogaster

Alignment Length:	620	Identity:	137/620 - (22%)
Similarity:	197/620 - (31%)	Gaps:	250/620 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CKVCGDRSSGKHYGIYSCDGCSGFFKRSIHR-NRIYTCKATGDLKGRCPVDKTHRNQCRACRLAK 76
            |||||:.::|.|:|.::|:||..||.||.:. :.|..||..|:    |.::|.:|..|:||||.|
  Fly    14 CKVCGEPAAGFHFGAFTCEGCKSFFGRSYNNLSSISDCKNNGE----CIINKKNRTACKACRLKK 74

  Fly    77 CFQSAMNKDAVQHERGPRKPKLHPQLHHHHHHAAAAAAAAHHAAAAHHHHHHHHHAHAAAAHHAA 141
            |....|:|...::.|.....|:|..|......|.||.||          ||:...|...::..:.
  Fly    75 CLMVGMSKSGSRYGRRSNWFKIHCLLQEQQQQAVAAMAA----------HHNSQQAGGGSSGGSG 129

  Fly   142 ------------------VAAAAASGLHHHHHAMP-VSLVTN---------------VSASFNYT 172
                              .|||||.|:..|....| :..|.|               :..|..|.
  Fly   130 GGQGMPNGVKGMSGVPPPAAAAAALGMLGHPGGYPGLYAVANAGGSSRSKEELMMLGLDGSVEYG 194

  Fly   173 QHISTHP----PAPAAPPSG----------------FHLTASGAQQGPAPPAGHLHHGGAGHQHA 217
            .|  .||    |:.::|.|.                .||.......|.:..|...|.||.|
  Fly   195 SH--KHPVVASPSVSSPDSHNSDSSVEVSSVRGNPLLHLGGKSNSGGSSSGADGSHSGGGG---- 253

  Fly   218 TAFHHPGHGHA----------------LPAPHGGVVSNPGGNSSAISGSGPGSTLPFPSHLL--- 263
                  |.|..                ||.|..|:.|.|        ...|.:.|| |||||
  Fly   254 ------GGGGGVTPGRPPQMRKDLSPFLPLPFPGLASMP--------VMPPPAFLP-PSHLLFPG 303

  Fly   264 -------HHN--LIAEAASKLPGITATAVAAVVSST---------STPYAS----------AAQT 300
                   ||.  |......:...:.|.||..:.:|:         ::|:|:          .|..
  Fly   304 YHPALYSHHQGLLKPTPEQQQAAVAAAAVQHLFNSSGAGQRFAPGTSPFANHQQHHKEEDQPAPA 368

  Fly   301 SSPS---SNNH-----------------------NYSSPSPSNSI-------QSISSI------- 325
            .|||   :|||                       ...||.|:..:       .|||::
  Fly   369 RSPSTHANNNHLLTNGGAADELTKRFYLDAVLKSQQQSPPPTTKLPPHSKQDYSISALVTPNSES 433

  Fly   326 -----------------------GSRSGGGEEGLSLGSESPRVNVETE---------TPSPSNSP 358
                                   |:.....||.|.:....|....:.|         .|||....
  Fly   434 GRERVKSRQNEEDDEARADGIIDGAEHDDEEEDLVVSMTPPHSPAQQEERTPAGEDPRPSPGQDN 498

  Fly   359 PLSAGSISPAPTLTTSSGSPQ---------------------------HRQMSRHSLSEATTPPS 396
            |:.....:...:|::.|.||:                           ..::|....::......
  Fly   499 PIDLSMKTTGSSLSSKSSSPEIEPETEISSDVEKNDTDDDDEDLKVTPEEEISVRETADPEIEED 563

  Fly   397 HASLMICA--------------SNNNNNNNNNNNN 417
            |:|....|              ||||||||||||:
  Fly   564 HSSTTETAKTSIENTHNNNNSISNNNNNNNNNNNS 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	32/85 (38%)
dsf	NP_001260109.1	NR_LBD_Tlx_PNR_like	467..671	CDD:132748
knrl	NP_001303368.1	NR_DBD_like	12..96	CDD:295381	32/85 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910