DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dsf and ftz-f1

DIOPT Version :9

Sequence 1:	NP_001260109.1	Gene:	dsf / 33823	FlyBaseID:	FBgn0015381	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_524143.2	Gene:	ftz-f1 / 40045	FlyBaseID:	FBgn0001078	Length:	1027	Species:	Drosophila melanogaster

Alignment Length:	732	Identity:	154/732 - (21%)
Similarity:	240/732 - (32%)	Gaps:	260/732 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GDRLLDIP------CKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDK 63
            |..::|..      |.||||:.||.|||:.:|:.|.|||||::...::|||.|    :..|.:||
  Fly   494 GGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVA----ERSCHIDK 554

  Fly    64 THRNQCRACRLAKCFQSAMNKDAVQHE--RGPRKPKLHPQLHHHHHHAAAAAAAAHHAAAAHHHH 126
            |.|.:|..||..||.:..|..:||:.:  ||.|. |..|......
  Fly   555 TQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRN-KFGPMYKRDR-------------------- 598

  Fly   127 HHHHHAHAAAAHHAAVAAAAASGLHHHHHAM-PVSLVTNVSASF-------NYTQHISTHPPAPA 183
                      |....|.......|....::| |....|.:|..:       |..|.|..
  Fly   599 ----------ARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQI------ 647

  Fly   184 APPSGFHLTASGAQQGPAPPAGHLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAIS 248
              |....||.| ....|:|.|..|     |..:|:.              |||::.|  .::...
  Fly   648 --PQVSSLTQS-PDSSPSPIAIAL-----GQVNAST--------------GGVIATP--MNAGTG 688

  Fly   249 GSGPGSTLPFPSHLLHHNLIAEAASKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNNHNYSSP 313
            ||| |..|..||.:.:.|                                 :|:.|||.:|.||
  Fly   689 GSG-GGGLNGPSSVGNGN---------------------------------SSNGSSNGNNNSS- 718

  Fly   314 SPSNSIQSISSIGSRSGGGEEGLSLGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSP 378
              :.:..|....|:.:|||..|                                     |:|...
  Fly   719 --TGNGTSGGGGGNNAGGGGGG-------------------------------------TNSNDG 744

  Fly   379 QHRQMSRHSLSEATTPPSHASLMICASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSG 443
            .||                             |..|.|:..|:                    :|
  Fly   745 LHR-----------------------------NGGNGNSSCHE--------------------AG 760

  Fly   444 VGSTCNTASSS---------SGFLELLLSPDKCQELI----------QYQVQHNTLLFPQQLLDS 489
            :||..|||.|.         |...:.|:.|.:...:|          ::|.|...||..|.....
  Fly   761 IGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQV 825

  Fly   490 RLLSWEMLQETTARLLFMAVRWVKCLMPFQTLSKNDQHLLLQESWKELFLLNLAQWTIPLDLTPI 554
            .:..:|::.:...:.||..|.|.:..:.|:.|..:||..|||.||.::.:|:
  Fly   826 EVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLD------------- 877

  Fly   555 LESPLIRERVLQDEATQTEMKTIQ--------------------EILCRFRQITPDGSEVGCMKA 599
                .:..|:......:|::...|                    |:..:.:.:..|..:..|||.
  Fly   878 ----HLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKF 938

  Fly   600 IALFAPETAGLCDVQPVEMLQDQAQCILSDHVRLRYPRQATRFGRLLLLLPSLRTIRAATIEALF 664
            :.|..|...|:.:.:.|....|..|..|.|:....||....:|..|:.:||.:..:.....:.|:
  Fly   939 LILLNPSVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFRGLVNILPEIHAMAVRGEDHLY 1003

  Fly   665 FKETIGNVPIARLLRDM 681
            .|...|:.|...||.:|
  Fly  1004 TKHCAGSAPTQTLLMEM 1020

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	39/100 (39%)
dsf	NP_001260109.1	NR_LBD_Tlx_PNR_like	467..671	CDD:132748	45/233 (19%)
ftz-f1	NP_524143.2	NR_DBD_Lrh-1_like	508..600	CDD:143541	39/126 (31%)
ftz-f1	NP_524143.2	NR_LBD_Ftz-F1_like	794..1024	CDD:132742	50/244 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910