Protein Alignment dsf and HNF4A

DIOPT Version :9

• Sequence 1: NP_001260109.1
• Gene: dsf / 33823
• FlyBaseID: FBgn0015381
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_005260464.1
• Gene: HNF4A / 3172
• HGNCID: 5024
• Length: 513
• Species: Homo sapiens
• Alignment Length: 671
• Identity: 124/671 - (18%)
• Similarity: 181/671 - (26%)
• Gaps: 359/671 - (53%)

  Fly    13 CKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLAKC 77
            |.:||||::|||||..|||||.|||:||:.:|.:|:|:    ...:|.|||..|||||.|||.||
Human    99 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCR----FSRQCVVDKDKRNQCRYCRLKKC 159

  Fly    78 FQSAMNKDAVQHERGPRKPKLHPQLHHHHHHAAAAAAAAHHAAAAHHHHHHHHHAHAAAAHHAAV 142
            |::.|.|:|||:||
Human   160 FRAGMKKEAVQNER--------------------------------------------------- 173

  Fly   143 AAAAASGLHHHHHAMPVSLVTNVSASFNYTQHISTHPPAPAAPPSGFHLTASGAQQGPAPPAGHL 207
                                          ..|||.
Human   174 ------------------------------DRISTR----------------------------- 179

  Fly   208 HHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSGPGSTLPFPSHLLHHNLIAEAA 272
                                               .||                        ...
Human   180 -----------------------------------RSS------------------------YED 185

  Fly   273 SKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNNHNYSSPSPSNSIQSISSIGSRSGGGEEGLS 337
            |.||.|.|...|.|:|         .|.:||                  :|.|
Human   186 SSLPSINALLQAEVLS---------RQITSP------------------VSGI------------ 211

  Fly   338 LGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSPQHRQMSRHSLSEATTPPSHASLMI 402
                                                                             
Human   212 ----------------------------------------------------------------- 211

  Fly   403 CASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSGVGSTCNTASSSSGFLELLLSPDKC 467
                          ||:.:.....|                                   ..|.|
Human   212 --------------NGDIRAKKIAS-----------------------------------IADVC 227

  Fly   468 QELIQYQVQHNTLLFPQQLLDSRLLSWEMLQETTARLLFMAVRWVKCLMPFQTLSKNDQHLLLQE 532
            :.:            .:|||                   :.|.|.|.:..|..|..:||..||:.
Human   228 ESM------------KEQLL-------------------VLVEWAKYIPAFCELPLDDQVALLRA 261

  Fly   533 SWKELFLLNLAQWTIPLDLTPILESPLIRERVLQD--EATQTEMKTIQEILCRFRQITPDGSEVG 595
            ...|..||...:.::......:|.:..|..|...:  |.::..::.:.|::..|:::..|.:|..
Human   262 HAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYA 326

  Fly   596 CMKAIALFAPETAGLCDVQPVEMLQDQAQCILSDHVRLRYPRQATRFGRLLLLLPSLRTIRAATI 660
            .:|||..|.|:..||.|...::.|:.|.|..|.|::..|......|||.||||||:|::|....|
Human   327 YLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMI 391

  Fly   661 EALFFKETIGNVPIARLLRDM 681
            |.:.|.:..|...|..||::|
Human   392 EQIQFIKLFGMAKIDNLLQEM 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	45/84 (54%)
		NR_LBD_Tlx_PNR_like	467..671	CDD:132748	52/205 (25%)
HNF4A	XP_005260464.1	NR_DBD_HNF4A	99..174	CDD:143518	45/159 (28%)
		NR_LBD_HNF4_like	190..412	CDD:132729	70/405 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910