Protein Alignment dsf and ESRRA

DIOPT Version :9

• Sequence 1: NP_001260109.1
• Gene: dsf / 33823
• FlyBaseID: FBgn0015381
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_016872802.1
• Gene: ESRRA / 2101
• HGNCID: 3471
• Length: 433
• Species: Homo sapiens
• Alignment Length: 682
• Identity: 114/682 - (16%)
• Similarity: 183/682 - (26%)
• Gaps: 356/682 - (52%)

  Fly    13 CKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLAKC 77
            |.||||.:||.|||:.||:.|..||||:|..:..|:|.|:.:    |.:.|..|..|:|||..||
Human    89 CLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE----CEITKRRRKACQACRFTKC 149

  Fly    78 FQSAMNKDAVQHER---GPRKPKLHPQLHHHHHHAAAAAAAAHHAAAAHHHHHHHHHAHAAAAHH 139
            .:..|.|:.|:.:|   |.:|.|..|::
Human   150 LRVGMLKEGVRLDRVRGGRQKYKRRPEV------------------------------------- 177

  Fly   140 AAVAAAAASGLHHHHHAMPVSLVTNVSASFNYTQHISTHPPAPAAPPSGFHLTASGAQQGPAP-P 203
                                                   .|.|.                |.| |
Human   178 ---------------------------------------DPLPF----------------PGPFP 187

  Fly   204 AGHLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSGPGSTLPFPSHLLHHNLI 268
            ||.|                                      |::| ||..|....:.|:.|.|:
Human   188 AGPL--------------------------------------AVAG-GPRKTAAPVNALVSHLLV 213

  Fly   269 AEAASKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNNHNYSSPSPSNSIQSISSIGSRSGGGE 333
            .| ..||                                  |:.|.|:.
Human   214 VE-PEKL----------------------------------YAMPDPAG---------------- 227

  Fly   334 EGLSLGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSPQHRQMSRHSLSEATTPPSHA 398
                                                                        |..|.
Human   228 ------------------------------------------------------------PDGHL 232

  Fly   399 SLMICASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSGVGSTCNTASSSSGFLELLLS 463
                                                       ..|.:.|:
Human   233 -------------------------------------------PAVATLCD-------------- 240

  Fly   464 PDKCQELIQYQVQHNTLLFPQQLLDSRLLSWEMLQETTARLLFMAVRWVKCLMPFQTLSKNDQHL 528
                             ||.::::                   :.:.|.|.:..|.:||.:||..
Human   241 -----------------LFDREIV-------------------VTISWAKSIPGFSSLSLSDQMS 269

  Fly   529 LLQESWKELFLLNLAQWTIPLDLTPILESPLIRERVLQDEATQT----EM-KTIQEILCRFRQIT 588
            :||..|.|:.:|.:||.::||.    .|.....:.||.:|..:.    |: ..:.:::.|.:.:.
Human   270 VLQSVWMEVLVLGVAQRSLPLQ----DELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALR 330

  Fly   589 PDGSEVGCMKAIALFAPETAGLCDVQPVEMLQDQAQCILSDHVRLRY----PRQATRFGRLLLLL 649
            .:..|...:||:||...::..:.|.:.||.|::.....|.::...|.    ..:..|.|||||.|
Human   331 LEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTL 395

  Fly   650 PSLRTIRAATIEALFFKETIGNVPIARLLRDM 681
            |.||......:...:..:..|.||:.:|..:|
Human   396 PLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEM 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	36/87 (41%)
		NR_LBD_Tlx_PNR_like	467..671	CDD:132748	45/212 (21%)
ESRRA	XP_016872802.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910