DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsf and ESR2

DIOPT Version :9

Sequence 1:	NP_001260109.1	Gene:	dsf / 33823	FlyBaseID:	FBgn0015381	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_001428.1	Gene:	ESR2 / 2100	HGNCID:	3468	Length:	530	Species:	Homo sapiens

Alignment Length:	108	Identity:	45/108 - (41%)
Similarity:	58/108 - (53%)	Gaps:	5/108 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLAKC 77
            |.||.|.:||.|||::||:||..||||||..:..|.|.||    .:|.:||..|..|:||||.||
Human   149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPAT----NQCTIDKNRRKSCQACRLRKC 209

  Fly    78 FQSAMNKDAVQHER-GPRKPKLHPQLHHHHHHAAAAAAAAHHA 119
            ::..|.|...:.|| |.|..:.........|.|..|..:..||
Human   210 YEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHA 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	40/85 (47%)
dsf	NP_001260109.1	NR_LBD_Tlx_PNR_like	467..671	CDD:132748
ESR2	NP_001428.1	Modulating	1..148
		ERbeta_N	16..122	CDD:289279
		NR_DBD_ER	144..225	CDD:143545	38/79 (48%)
		NR_LBD_ER	263..498	CDD:132747
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	507..530
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910