DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dsf and nhr-262

DIOPT Version :9

Sequence 1:	NP_001260109.1	Gene:	dsf / 33823	FlyBaseID:	FBgn0015381	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_507272.2	Gene:	nhr-262 / 184235	WormBaseID:	WBGene00008619	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	294	Identity:	66/294 - (22%)
Similarity:	103/294 - (35%)	Gaps:	57/294 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLAKC 77
            |||||||.:...||..:|.||:.||:|::.:|..|.|..    :..|.:..|:||.||.||..||
Worm    36 CKVCGDRPNNDRYGASACLGCTVFFRRAVVKNLKYKCMK----EQNCLISCTYRNACRYCRFQKC 96

  Fly    78 FQSAMNKDAVQHER--GPRKPKLHPQLHHHHHHAAAAAAAAHHAAAAHHHHHHHHHAHAAAAHHA 140
            |...|:..|:|...  ||||.....::....::......|:........|..:........|.|.
Worm    97 FAVGMHSSAIQRRDLVGPRKISGDGEVIICENNTFLDDFASFQRTQFAEHLQYFTEHQVDVAFHV 161

  Fly   141 AVAAAAASGLHHHHHAMPVSLVTNVSASFNYTQHISTHPPAPAAPPS--------GFHLTASGAQ 197
            ..|...........|.:.|.|...:..:..:...:......||....        .|:|...|.:
Worm   162 DQANVVKFRRRARAHDVNVMLKLCLKQATEWANRLKLFKSLPAESKRSILAEYCLAFNLIDQGYK 226

  Fly   198 QGPAPPAG--HLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSGPGSTLPFPS 260
            .......|  .|.:|        :|.||.:...|             |.:::........:.
Worm   227 TSKEADLGIWLLQNG--------SFMHPDYFFGL-------------NVTSVDEESMKVKIQ--- 267

  Fly   261 HLLHHNLIAEAASKLPGITATAVAAVVSSTSTPY 294
              ||||.:||               :::..|||:
Worm   268 --LHHNFVAE---------------MINCLSTPF 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	36/86 (42%)
dsf	NP_001260109.1	NR_LBD_Tlx_PNR_like	467..671	CDD:132748
nhr-262	NP_507272.2	NR_DBD_HNF4A	36..110	CDD:143518	32/77 (42%)
nhr-262	NP_507272.2	HOLI	182..359	CDD:214658	23/144 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910