DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dsf and nhr-28

DIOPT Version :9

Sequence 1:	NP_001260109.1	Gene:	dsf / 33823	FlyBaseID:	FBgn0015381	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_001024388.1	Gene:	nhr-28 / 181705	WormBaseID:	WBGene00003624	Length:	437	Species:	Caenorhabditis elegans

Alignment Length:	186	Identity:	49/186 - (26%)
Similarity:	70/186 - (37%)	Gaps:	50/186 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PCKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTHRNQCRACRLAK 76
            ||.|||:...|.|:|..:|..|:.||:||:..|:.|.|:|    .|.|.:.|..|..|||||..|
Worm     7 PCSVCGEAGDGAHFGAEACRACAAFFRRSVALNKAYVCRA----MGTCVIQKNVRCMCRACRFTK 67

  Fly    77 CFQSAMNKDAVQHER-----------GPRKPKLHP----------------------QLHHHHHH 108
            |....|.|.|||..|           ....|::.|                      ||:.:::.
Worm    68 CIAVGMRKSAVQRHRELFASQETSSESSSNPRISPTLSWPMDISPQSYEETGMPTLSQLNENYNQ 132

  Fly   109 AAAAAAAAHHAAAAHHHHHHHHHAHAAAAHHAAVAAAAASGLHHHHHAMPVSLVTN 164
            .:......|:....:..|..         ...|||...|    |:.|...:.||.:
Worm   133 MSTVRRVIHNTGGDNIFHRR---------EPKAVAYTDA----HNVHLKEIGLVAD 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	36/96 (38%)
dsf	NP_001260109.1	NR_LBD_Tlx_PNR_like	467..671	CDD:132748
nhr-28	NP_001024388.1	ZnF_C4	7..76	CDD:197701	30/72 (42%)
nhr-28	NP_001024388.1	HOLI	168..345	CDD:214658	2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910