Protein Alignment dsf and nhr-34

DIOPT Version :9

• Sequence 1: NP_001260109.1
• Gene: dsf / 33823
• FlyBaseID: FBgn0015381
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_001023245.1
• Gene: nhr-34 / 177800
• WormBaseID: WBGene00003627
• Length: 631
• Species: Caenorhabditis elegans
• Alignment Length: 710
• Identity: 132/710 - (18%)
• Similarity: 210/710 - (29%)
• Gaps: 311/710 - (43%)

  Fly     1 MGTAGDRLLDIPCKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLKGRCPVDKTH 65
            ||........:.|:||||..:|:|||..:|:||.|||:|||...|.|.|:    ..|:|.|.:.:
 Worm   139 MGNVQSEFTGLKCRVCGDSRAGRHYGTIACNGCKGFFRRSIWEQRDYVCR----FGGKCLVVQEY 199

  Fly    66 RNQCRACRLAKCFQSAMNKDAVQHERGPRKPKLHPQLHHHHHHAAAAAAAAHHAAAAHHHHHHHH 130
            ||:||||||.|||...|:..|||.||...|
 Worm   200 RNRCRACRLRKCFTVGMDARAVQSERDKHK----------------------------------- 229

  Fly   131 HAHAAAAHHAAVAAAAASGLHHHHHAMPVSLVTNVSASFNYTQHISTHPPAPAAPPSGFHLTASG 195
                                                                             
 Worm   230 ----------------------------------------------------------------- 229

  Fly   196 AQQGPAPPAGHLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSGPGSTLP-FP 259
                                                      .||..:::      .|||.| :|
 Worm   230 ------------------------------------------KNPKDSNN------EGSTSPQYP 246

  Fly   260 SHLLHHNLIAEAASKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNNHNYSSPSPSNSIQSISS 324
                               ||:      :..|.|..|.:||.:.|.|::|:         |:|..
 Worm   247 -------------------TAS------TPISIPSTSTSQTPTSSVNSYNF---------QNIPG 277

  Fly   325 IGSRSGGGEEGLSLGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSPQHRQMSRH--S 387
            |.|||  ..|.|.:               ..||.|:..         |:.|.:..|..:.|:  .
 Worm   278 IVSRS--FSENLIM---------------RDNSVPVME---------TSQSAALSHVPLVRYLID 316

  Fly   388 LSEATTPPSHASLMICASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSGVGSTCNTAS 452
            |.:||             :|..:.|.:..:.|..|                  ...|..|...|.
 Worm   317 LEKAT-------------DNLIDENCDFMSMEFDQ------------------LCRVDVTIEAAF 350

  Fly   453 SSSGFLELLLSPDKCQELIQYQVQHNTLLFPQQLLDSRLLSWEMLQETTARLLFMAVRWVKCLMP 517
            ...|.                 |...|.  |:.|...||.:.|.:.....|...:.:.:.|.:..
 Worm   351 RQPGV-----------------VAKRTP--PRWLALERLTTLEDVHIAWCRSFVLCIDYAKIMKD 396

  Fly   518 FQTLSKNDQHLLLQE-----SW------------KELFLLNLAQWTIPLDLTPILES------PL 559
            :|.||..||..||:.     :|            ..:.|:|.:.:....:|...|:.      .:
 Worm   397 YQELSPTDQFTLLRNRVISVNWLCHTYKTFKAGCDGVALVNGSWYPRDKELQKQLDPGCNHYFRI 461

  Fly   560 IRERVLQDEATQTEMKTIQEILCRFRQITPDGSEVGCMKAIALFAP----ETAGLCDVQPV--EM 618
            :.|.:::|            ::...|::..|..|...:||:.||..    ...|...::.|  :.
 Worm   462 LSEHLMED------------LVIPMREMDMDEGEFVILKALILFRAHRRLSEEGRAHIKRVRDKY 514

  Fly   619 LQDQAQCILSDHVRLRYPRQATRFGRLLLLLPSLRTIRAATIE-----ALFFKETIGNVP 673
            ::...|.:...|......:.:.|..::||||||:..:.....:     |||....:..:|
 Worm   515 IEALYQHVQHQHRHFSSVQTSMRISKILLLLPSIEHLSQQEDDNVQFLALFNLANLNGLP 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	42/92 (46%)
		NR_LBD_Tlx_PNR_like	467..671	CDD:132748	44/237 (19%)
nhr-34	NP_001023245.1	NR_DBD_HNF4A	151..226	CDD:143518	40/78 (51%)
		HOLI	380..551	CDD:214658	34/182 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910