Protein Alignment dsf and Nr2f1

DIOPT Version :9

• Sequence 1: NP_001260109.1
• Gene: dsf / 33823
• FlyBaseID: FBgn0015381
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_034281.2
• Gene: Nr2f1 / 13865
• MGIID: 1352451
• Length: 420
• Species: Mus musculus
• Alignment Length: 696
• Identity: 153/696 - (21%)
• Similarity: 211/696 - (30%)
• Gaps: 370/696 - (53%)

  Fly     2 GTAGDR----------LLDIPCKVCGDRSSGKHYGIYSCDGCSGFFKRSIHRNRIYTCKATGDLK 56
            |||||:          ...|.|.||||:|||||||.::|:||..|||||:.||..|||:|..:
Mouse    62 GTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRN-- 124

  Fly    57 GRCPVDKTHRNQCRACRLAKCFQSAMNKDAVQHERGPRKPKLHPQLHHHHHHAAAAAAAAHHAAA 121
              ||:|:.|||||:.|||.||.:..|.::|||..|.|
Mouse   125 --CPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMP---------------------------- 159

  Fly   122 AHHHHHHHHHAHAAAAHHAAVAAAAASGLHHHHHAMPVSLVTNVSASFNYTQHISTHPPAPAAPP 186
                                                                             
Mouse   160 ----------------------------------------------------------------- 159

  Fly   187 SGFHLTASGAQQGPAPPAGHLHHGGAGHQHATAFHHPGHGHALPAPHGGVVSNPGGNSSAISGSG 251
                         |..|                                   |||
Mouse   160 -------------PTQP-----------------------------------NPG---------- 166

  Fly   252 PGSTLPFPSHLLHHNLIAEAASKLPGITATAVAAVVSSTSTPYASAAQTSSPSSNNHNYSSPSPS 316
                                                        ..|.|:....|.|.|.|
Mouse   167 --------------------------------------------QYALTNGDPLNGHCYLS---- 183

  Fly   317 NSIQSISSIGSRSGGGEEGLSLGSESPRVNVETETPSPSNSPPLSAGSISPAPTLTTSSGSPQHR 381
                                                                             
Mouse   184 ----------------------------------------------------------------- 183

  Fly   382 QMSRHSLSEATTPPSHASLMICASNNNNNNNNNNNNGEHKQSSYTSGSPTPTTPTPPPPRSGVGS 446
                          .:.||::.|.                                |.|.|..||
Mouse   184 --------------GYISLLLRAE--------------------------------PYPTSRYGS 202

  Fly   447 TCNTASSSSGFLELLLSPDKCQELIQYQVQHNTLLFPQQLLDSRLLSWEMLQETTARLLFMAVRW 511
            .|             :.|                        :.::..|.:.|..|||||.||.|
Mouse   203 QC-------------MQP------------------------NNIMGIENICELAARLLFSAVEW 230

  Fly   512 VKCLMPFQTLSKNDQHLLLQESWKELFLLNLAQWTIPLDLTPIL------ESPLIRERVLQDEAT 570
            .:.:..|..|...||..||:.:|.|||:||.||.::||.:.|:|      .||:..:||:   |.
Mouse   231 ARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVV---AF 292

  Fly   571 QTEMKTIQEILCRFRQITPDGSEVGCMKAIALFAPETAGLCDVQPVEMLQDQAQCILSDHVRLRY 635
            ...::..||.:.:.:.:..|.:|..|:|||.||..:..||.|...:|.||:::||.|.::||.:|
Mouse   293 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQY 357

  Fly   636 PRQATRFGRLLLLLPSLRTIRAATIEALFFKETIGNVPIARLLRDM 681
            |.|.:|||:|||.||||||:.::.||.|||...:|..||..|:|||
Mouse   358 PNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDM 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dsf	NP_001260109.1	NR_DBD_TLX	5..98	CDD:143537	48/102 (47%)
		NR_LBD_Tlx_PNR_like	467..671	CDD:132748	74/209 (35%)
Nr2f1	NP_034281.2	NR_DBD_COUP_TF	83..155	CDD:143516	42/75 (56%)
		NR_LBD_COUP-TF	181..416	CDD:132746	93/378 (25%)
		Important for dimerization	341..420		34/63 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910