DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bchs and AT1G58230

DIOPT Version :9

Sequence 1:	NP_608968.2	Gene:	bchs / 33819	FlyBaseID:	FBgn0043362	Length:	3489	Species:	Drosophila melanogaster
Sequence 2:	NP_001322631.1	Gene:	AT1G58230 / 842191	AraportID:	AT1G58230	Length:	2604	Species:	Arabidopsis thaliana

Alignment Length:	3075	Identity:	644/3075 - (20%)
Similarity:	1104/3075 - (35%)	Gaps:	936/3075 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   561 AAHVQKITKGDESVVVEL--ENESEEELFDTLGKHVLEALTMLLGGGASNNAQLFREYGGAKCVH 623
            |:|:..:     ||:::.  ::.|...:.:.|.:.:|.:|..     ::.|...|:...||..|.
plant    17 ASHLPSV-----SVLLDALEQSASTPRIANGLSQRLLRSLQF-----SNENKLSFKALNGACRVL 71

  Fly   624 ELVKFKHCRPQALGIVRELILSAGGDDDMLHILSLMHSVSPLQ---------VEFKIQILNMLLG 679
            .|...:....:..|.|..|:.|:    |...|:...|..|...         ||..:.|......
plant    72 RLACIQAKESRKSGCVSPLVESS----DCGVIVDSPHKKSDSSHTEDCWFECVESCVGIFTEFFS 132

  Fly   680 CLKDSHRTRTVFRKVGGFVYVTSVFVSLDGSMALPQPDIPQQDLILLLQIVFQTLATAMRFEPAN 744
            ...|:.            |||....|.:|....|......:.:       |.:.:...|:..|
plant   133 STNDAK------------VYVLRSSVCVDCLFELFWEKAVRNN-------VMKLIIDLMKIRP-- 176

  Fly   745 AKFFHQEISSSSLCD---TLRLLGCFGGSSALQDYTGTYEPQQSLLKYYHEIFSG--DILSVSFS 804
                        ||:   :.:|..|   |..|:.:|...|.:...:....::.:|  |::.   |
plant   177 ------------LCEEDKSAKLQVC---SKYLETFTQVKERENDSVDLSVDLLAGMRDLIK---S 223

  Fly   805 EDVPYPLSYVCIVFR----LLYSIAL--DNFEAPN--------LSGIITLFSDPPTTLRSPSKEL 855
            :.     .|...:||    .|:.::|  .|.:..|        |..:.:|.::..|: :...|.|
plant   224 DS-----RYYQALFREGECFLHIVSLLNGNLDEANGEKLVLNVLQTLTSLLANNDTS-KFAFKAL 282

  Fly   856 A----PPVHPSQLNLTQPSPEPRIVHPGVVLCMLQLLPAVEYDMAPLQAVQ----LQVYLSEIIK 912
            |    ..:....|:..|..|..|::.     .:|.:|...::|......::    :.:||:.:.|
plant   283 AGKGYQTLQSLLLDFFQWKPTQRLLD-----ALLDMLVDGKFDDKGSALIKNEDVIILYLNVLQK 342

  Fly   913 SLVRSERNQQIMCDHG--LAEKLLK--LTRRALAEESHPLHVPMQYI-LERLAAQALQPTELRQF 972
            |      ::.:.| :|  |.::||:  ::.||....:..||:.:.:. ||...:..|:.|:|.|.
plant   343 S------SESLQC-YGLNLFQQLLRDSISNRASCVRAGMLHLLLDWFSLENDDSVILKITQLTQT 400

  Fly   973 LRLGEPLSCADI----DLQQPYKLGGPVPLTRIKTLVSMTTPRDFRAHGSSTLPPFVELDMSAEG 1033
            :. |..:|..||    .|.:..::|..   .|.::|:
plant   401 IG-GHSISGKDIRKIFALLRSERVGNQ---QRYRSLL---------------------------- 433

  Fly  1034 FGCLYLPSLAPQATATAGGTIDANSIGGIGAGDRI-----FPPQTGLTYSTWFCVEKFSD----- 1088
            ..||.  |:..:...|  |..|.|   |:.:|..|     :|...|.::..|..||.|..
plant   434 LACLL--SMLNEKGPT--GFFDMN---GVESGIVIRTPVQWPANKGFSFCCWLRVESFPGDGKMG 491

  Fly  1089 -----PKTDPHCVRLLTLVRTIHNPREENLACLSILLSARDKAIVVSTQETLVTPRKSIGDWEPE 1148
                 .|....|...|         .::.|:.:|:.|    |...|:....||..:
plant   492 IFSFMSKNGKGCFAAL---------GKDGLSYVSLNL----KRQCVNVHTNLVCKK--------- 534

  Fly  1149 GSDDGIARIWCPDLLHEGQWHNLVV--VLNRAVLKNSSLFLYLDGVPMHTQKLHY---------- 1201
                               ||.:.|  .:.||....|.|..|::|..:.:::..|
plant   535 -------------------WHFICVSHSIGRAFWGGSLLRCYVNGDLVSSERCSYPKVTDVLTSC 580

  Fly  1202 -----IAQHPAAGNASLTSPTQIFGYIGTPPIWRRYSRLCWKQGVCHLIEDVLTQQTVQTIYQLG 1261
                 |.......|..|.|...:|.:.|             :.|..:|..|.|:.:.||.||.||
plant   581 LIGTRITLPHIQDNDGLESIRDVFPFFG-------------QIGPVYLFNDSLSSEQVQAIYSLG 632

  Fly  1262 PHYMGSLQAPQL---------------GKQSESLAPLVPEDRVLLGLNAKAVSKLTLVKIRKVYS 1311
            |.||.:....::               ||  :.||     .:|..||||:|.....|..:.:|..
plant   633 PSYMYAFLENEMTCPFSDNPFPSGILDGK--DGLA-----SKVSFGLNAQASDGRRLFNVSRVSD 690

  Fly  1312 RADNKSIAKQLNMNSHENATPIKILHNSAGHLAGAGRSLGGVVVGYLGVRVFSPHPVSAMIDTVG 1376
            ....: :|.:.::                                .:|.::.|...:..:|..||
plant   691 HLQER-LAFEADI--------------------------------MVGTQLCSRRLLQQIIYCVG 722

  Fly  1377 GCNVLLGIIAMAQDVESLYAG----------------VKALTCVVRSNRAAQAEMDRKRCYQTLG 1425
            |.:|...:|..:...||....                ::.:..|:..|.|.|.:|.....:..||
plant   723 GISVFFPLITQSDRCESETLNEETSAMPTKERMTAEVIELIASVLDENPANQQQMHLLAGFPILG 787

  Fly  1426 MFFKK-KKHLLN----SHILHLTFGLVGTVNSGQDMSAIPNVTAFQDLLCDLEIWHNAPNGLLRS 1485
            ...:. :...||    |.:.|| |.::.:....:.:..    .|...:..:..||.:|...:.|.
plant   788 FLLQSIQPKQLNLETLSSLKHL-FNVISSSGFAEQLVE----DAISSIFLNPHIWLHAAYNVQRE 847

  Fly  1486 LLEHLLELVVESSDKKQNVKIMRDLQLLVKLLHIITQIQDHSTREILFSLLETLLGGQPRHTDLL 1550
            |...|::.:      ..:.:::..|..|.:::.|:......|.|
plant   848 LYMFLIQQL------DNDPRLLGSLCRLPRVIDIVWNFYWESER--------------------- 885

  Fly  1551 LFGQYVAAKLPHAHSGGLERAVLLPSMKNPAEDQDGGVAQNIYLRNRCLSLLHGLLFTPRN---- 1611
                |.....|..|.   .|.:    .:.|:.|:...:        |.|.|..|.:...:|
plant   886 ----YCKGSKPLMHP---TRTI----AERPSRDEIHKI--------RLLLLSLGEMSLRQNISSG 931

  Fly  1612 -----TVNYVICDDISKTLGMDWLLLFMQPHVHFTTVIIA------------------------V 1647
                 |..:..|.|::   .::.:|..:...:..|:|:::                        :
plant   932 DVKALTAFFETCQDVA---CIEDVLHMVIRAISQTSVLVSFLEQVNLIGGCHIFVDLLQRDYEPI 993

  Fly  1648 RILVVICANESFLVR--FRDATHNGGYLRFTEMVSQRKMLGLGAQQLNQRPTNGTGTVIVATPQN 1710
            |:|.:     .||.|  :...:...|...|...|.:.|.|..|.:::..|    |..:.:|....
plant   994 RLLSL-----QFLGRLLYDVPSERKGPKFFNLAVGRTKSLSQGHKKIGAR----TQPIFLAMSDR 1049

  Fly  1711 TIQHLPTQIAGEVRAAALNI--PGFQLLEWLMNH-------------HLDVPELYFLITALIMG- 1759
            ..|:..|.   .:||...::  .|....:.|..|             |..:|:::..|...:.|
plant  1050 LFQYPQTD---NLRATLFDVLLGGASPKQVLQKHNQVDKHRSKPSNSHFFLPQIFVFIFEFLSGC 1111

  Fly  1760 ----QPVKVLA-----TEHTKFDLDRVWSFLWGAPVSANTQLPKLNICPEGVCVLL--------- 1806
                ..:|:::     .:....:::.:..|.|.|.::|:.   ||::..:....||
plant  1112 KDGLARMKIISDILDLLDSNPMNVEALMEFGWSAWLTASM---KLDVIKDYRSELLNHDDLALNE 1173

  Fly  1807 -AMVRGI-----------VHGGECAPWLHSHPETIIQLLFSLYQNLTDFAPVMMTGDVVTSLVAV 1859
             ..|||:           |.||    | ....||:..:|.....|...:...:.  |:...|:..
plant  1174 QHFVRGLFCVVLCHYILSVKGG----W-QQLEETVNFILLQSEHNDVPYRSFLR--DLYEDLIQR 1231

  Fly  1860 LFPLASRPADSEPNSGASTPTDDT----------------GSSFALPPPETLHGAPQPKLTAHPV 1908
            |..|:     ||.|...|.|..|.                ||....|...|
plant  1232 LVELS-----SEDNIFLSHPCRDNVLYLLRLVDEMLVREFGSRLLFPAIST-------------- 1277

  Fly  1909 CNCIIDFLRVIVVDSLGLNMQGKPTPVIDLVLDAAPESAE--LPLQVQYQTQIIIALMDHLLAAD 1971
                 ||..    |.|.|..:..||..:|       ||.:  |..::...|:.
plant  1278 -----DFSE----DLLQLGNREDPTLGLD-------ESFQRFLTEEISRNTEC------------ 1314

  Fly  1972 VLVGEQAALPLVPLLQSQMQYIAPNVFYLTARIVDKLWQGCLARNPHDIFDFVIKLIVQAKRRSS 2036
                :|:...:..|:.::..:          .:.|.||                |:|.....|.
plant  1315 ----QQSCTTVTELMTNERWW----------NLYDNLW----------------KIICDINGRG- 1348

  Fly  2037 SLSLEHLHHSLNRSILFLLSRPTDDSRADQMSVLEALHKIIQHRLLIFGAGNHELEFIGCLTYCL 2101
                     .:..|...|.:.|:...||  ..::|:|:........:..:|.     ||......
plant  1349 ---------PVKMSPKSLATGPSIGQRA--RGLVESLNVPAAEMAAVVVSGG-----IGSALSGK 1397

  Fly  2102 LQLTADMKIILEPATSRNTTWHVNPQTETAEPKDEDLNQLQGRNLIVGAAFRVWEELYVCKKPAI 2166
            :....|..::|                     :.|...::         .||: ..||:|.. ::
plant  1398 MNKNVDKAMLL---------------------RGEKCPRI---------VFRL-VTLYLCMS-SL 1430

  Fly  2167 EEVFKV--SLTSPPPNSKAPDLQTTREQVMELASKLWFNYVEAERKATYRAPWELHTQIQSKIQK 2229
            |:..:.  .:||..|:..|.|.:.::.::......|.:                    ::|:..|
plant  1431 EKATRCVQQVTSLLPSFLAADDEQSKSRLHLFIGCLLY--------------------VRSQYGK 1475

  Fly  2230 VTGG-----LSRLTSRTKTKKEELVRTRSTLTREAAYESTGIHVQL------------------- 2270
            :..|     :|.|...|.:..:.::.| |.:.::.:.:|.||..::
plant  1476 LDDGARFHVISHLIRETVSCGKSILAT-SGMNKDDSSDSGGIFKEMGSIQNLIHKDRVLAAVTDE 1539

  Fly  2271 ---IKDLLDLRAKQYQQM-----------------------------------------LQH--T 2289
               :|.|:..|.:|.|.:                                         |.|  .
plant  1540 TTYMKTLISDRTRQVQALGERNNETLSIECNSKKAFDGELQNVLKTVVTWDENRRVSVQLSHEEQ 1604

  Fly  2290 QRYVYQDWVQSEMELTRERGLWG--PTGSCSLDKWILDTTEGPHRMRKKTMRNDVFYLHYPYRPE 2352
            |:.|.:.|:.....|..|||.|.  |..:..|::|.||.||...|.|.|..||..|.....:.|.
plant  1605 QQNVTEKWIHMLRSLMDERGPWSATPFPNNILNRWKLDRTEDSWRRRPKLRRNYHFDERLCHPPS 1669

  Fly  2353 LELADNRQLKYKVASSLDSKTYALHGPQQ---------PRILAEAGEHHAMQQQSSLEAVQSHRL 2408
            ...|...:....:.   :||:..:|.|:|         .||..|.|....  :..|.:|.||. :
plant  1670 TSTATENETSNVIN---ESKSGVIHIPEQMKKFLLKGIRRITDEGGSDSC--ENDSSQAEQSF-M 1728

  Fly  2409 ETSSSTSTPPPMVLPKLV--GHGSTPCPQESVDGNAPEDDEEEEDTSMTSDNETFLRLLEEQEKI 2471
            :||:.      :...:||  ..|.....|:.||.::.|....|..||:.      ..|:..:.|:
plant  1729 DTSAD------IQFSELVRTSSGLKDVVQDKVDASSLEVGTSEVLTSVP------CVLVTPKRKL 1781

  Fly  2472 SFMFRCARVQGLDTFEGLLLFGKEHCYIVDG---------FTLLKNREIRDIDT-------LPPG 2520
            :        ..|...:.:|.|..|  ::|:|         |:..|..::...:.       ..|.
plant  1782 A--------GWLAVMKNVLHFSGE--FLVEGTGGSAVFKNFSTSKGSDVTKAENKQNLVKWSSPY 1836

  Fly  2521 AYEPIIPNSGGTSSTTSRAVSHKLRQCSKFAYEEIREVHKRRYLLQPIALEVFSEDGRNYLLSFP 2585
            ..|..:....|..   ::....|:::..::...:::.||..|||||..|||:|.::      |.|
plant  1837 DSETFLDLESGNK---NKKPLKKVKRHRRWKIGKVKSVHWTRYLLQYTALEIFFQE------SVP 1892

  Fly  2586 RKVRNKVNQR-----FLALATALNDNAQQSVAGQKRTASVEQTAGIFSGLIGETSVTQRWVRGEI 2645
            ....|..:|:     .:.:.:..|:........:.|||.:.......:..:.||: ..||.|.||
plant  1893 PVFLNFASQKNAKEVGMLIVSTRNEFLFPKNVPRDRTAMISFVDRRIAMEMAETA-RDRWRRREI 1956

  Fly  2646 SNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEELDLTNPKTFRDFSRPMGAQAEERLEQFQ 2710
            :||:|||.||||||||||||.|||||||::|||.||.||.:...||||.|:|:||....|.|.|:
plant  1957 TNFEYLMILNTLAGRSYNDLTQYPVFPWVVADYSSETLDFSKASTFRDLSKPVGALDTRRFEIFE 2021

  Fly  2711 KRFKEWDDPHGETPPYHYGTHYSSAMIVCSYLVRLEPFSQPFLKLQGGHFDLADRMFHSIKEAWL 2775
            .|:..:.||  :.|.::||:||||...|..||:|||||:.....||||.||.|||:|.|::.::.
plant  2022 DRYHSFSDP--DIPSFYYGSHYSSMGSVLYYLLRLEPFTSLHRSLQGGKFDHADRLFQSVEGSFR 2084

  Fly  2776 SASKLNMADVKELIPEFFYLPEFLSNFNNFDLGTKQNGETLNHVILPPWAKHDPREFIRLHRSAL 2840
            :... |.:|||||||||||:||||.|.|::.||.||:||.|..|.||||||..|..||..:|.||
plant  2085 NCLS-NTSDVKELIPEFFYMPEFLVNSNSYHLGVKQDGEPLGEVCLPPWAKGSPEMFIARNREAL 2148

  Fly  2841 ECDYVSQHLHLWIDLIFGCKQQGPAAVDAVNVFHHLFYEGNVDIYNIDDPLKKNATIGFINNFGQ 2905
            |.:|||.|||.|||||||.||:|..||:|.|:|::|.|||.||:.|::|.|:.:|....|.||||
plant  2149 ESEYVSSHLHDWIDLIFGHKQRGKPAVEAANIFYYLTYEGAVDVENMEDQLQISAIEDQIANFGQ 2213

  Fly  2906 IPKQLFKKAHPAKK---------------------MGGSRHS-------ALID------------ 2930
            .|.|:|:|.||.:.                     :..:.||       .::|
plant  2214 TPIQIFRKKHPRRGPPIPIAHPLYFAPASINLSSILPATTHSPSAVLYVGVVDSNIVLVNQGLTL 2278

  Fly  2931 ------PTSLIQGNSTVLQT--DRLFFHNLDNLKPSLQPIKELKGPVGQILQPDKTVFAVEQNKV 2987
                  .|.|..|.:....:  |..|....|.|.|     :.:..|:...::.....||     .
plant  2279 SVKIWLTTQLHSGGNFTFSSAQDPFFGVGSDVLSP-----RNIGSPLADNVELGSQCFA-----A 2333

  Fly  2988 MMPPSYTKYIAWGFADHSLRIGLYDTDRASFVSEASAQNSGEILTCACPNA--KMIVTAGTSSVV 3050
            |..|.....::.|..::|..:......|.    ..|.::..::::|....|  .::.|....:.|
plant  2334 MQMPLENFLVSCGNWENSFHVISLTDGRV----VQSIRHHKDVVSCVAVTADSTILATGSYDTTV 2394

  Fly  3051 TIWKF---------------DANRKSLAV----KHSLHGHTDAVTCLAASAAYNVIVSGSRDGTA 3096
            .:|..               :..||.:.:    .|.|.||.|.:|||..|...::::|||:|||.
plant  2395 MVWDILRMRTPEKRVRNTHAEVLRKDIVIADAPSHILCGHDDIITCLYVSTDLDIVISGSKDGTC 2459

  Fly  3097 IVWDMTRFTFVRQLR------------GHAGVVAAVSINELTGDIATCSATWLHVWSINGDALAM 3149
            :...:....::|.|:            .|.|.:.....::|:          ||::||||..||
plant  2460 VFHTLREGRYIRSLKHPSGSAVSKLAASHHGRIVLYGDDDLS----------LHLYSINGKHLA- 2513

  Fly  3150 VNTCVGSADRMQQILCVAFSQIREW-----DQQNVII---------------------------- 3181
                  |::...:|.|:..|:..|:     ||..:|:
plant  2514 ------SSESNGRINCLELSKCGEFLVSAGDQGQIIVRSMNTLEVVKRYNGAGKIITSLTVTQEE 2572

  Fly  3182 ---TGSTDGVVRMWSLEHTQ 3198
               .|:.||.:.::|:|:.|
plant  2573 CFLAGTKDGALLVYSIENPQ 2592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bchs	NP_608968.2	PH_BEACH	2469..2600	CDD:275391	28/151 (19%)
		Beach	2638..2918	CDD:280327	157/279 (56%)
		WD40	<2991..3252	CDD:225201	54/277 (19%)
		WD40	2995..>3194	CDD:295369	50/267 (19%)
		WD40 repeat	3031..3070	CDD:293791	9/59 (15%)
		WD40 repeat	3075..3111	CDD:293791	11/35 (31%)
		FYVE_WDFY3	3418..3482	CDD:277259
AT1G58230	NP_001322631.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101142at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920