|
Fly 46 GRNAEEALMDARVQVSLTTLKKLFNEYTHPREPLSEQERDDKLYEMLPLFCKVFSSCPSNDMSEK 110
||..:|........:.|..|::||:|..||...::::|:::|||.|||:|.:||.:.|.:.|:||
Zfish 50 GRPRQEECSPQDNALGLMHLRRLFSELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSTMNEK 114
Fly 111 FWDVVAFCQQVSRLMVSEIRKRASNQSTEAASIAIVKFLEVETTEETSSGWMLLATLNLLANGDV 175
|.|::.|..|||||||:|||:||||:||||||.|||:||||..:||||.|||||.|:||||:...
Zfish 115 FSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEVNQSEETSRGWMLLTTINLLASSGQ 179
Fly 176 SLIQVMTAAAVPSTLVKCLYLFFDLPIVEDDEPSADGGAVSEFNAHERRTLLQKVFVQLLVKLCS 240
..:..||..:||||||||||||||||.: |.......:|....:||.||||||||:||||||
Zfish 180 KTVDCMTTMSVPSTLVKCLYLFFDLPHM----PEVPAATQTELPLADRRALLQKVFVQILVKLCS 240
Fly 241 YPYPAEELARMDDLTLLFSAITSPCPIHNIVWRKNAAEILTTISRNGLTDAVVSYIHSKGCMALC 305
:..||||||:.|||.||||||||.||.||:.|||:|.|:||||||:||:..||.|||.|.|::.|
Zfish 241 FVSPAEELAQKDDLQLLFSAITSWCPPHNLPWRKSAGEVLTTISRHGLSVNVVKYIHEKECLSTC 305
Fly 306 VDNMQRLTFGNPLEIVEMFVTVFCFLKDSSQVSQILMDDFRASQGYVFLSDFLLKFDNNRSQSLE 370
:.|||:....:||||||||..:.|||||||.|||.|:||||..|||.||.|.:::.:..:.. |
Zfish 306 IQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRMCQGYTFLIDLMIRLEQAKED--E 368
Fly 371 IQAAIRNLVLMISSLCMCGFYELRPPASQFNTAFKLQNFQLPQATSRETCVRNVYAFQVLQNVFL 435
.:.|:::||.::::|...|..||:|........|.|..|.:||.:.:...|||:.||.||||.||
Zfish 369 SKDALKDLVNLVTALTTYGVSELKPAGLTTGAPFLLPGFVVPQPSGKGHTVRNIQAFSVLQNAFL 433
Fly 436 KSTTPALCCTILDAISRVYHSENANYFILESEQTLSSFAERIHMKSPQIQEKFYDLLEFIVFQLN 500
|:.:..|...||:||:.:|.::.|||||||::.|||.||||: .|.|::|.|:::||||:||.||
Zfish 434 KAKSGRLARMILEAIANIYAADYANYFILEAQHTLSQFAERV-TKLPEVQSKYFELLEFVVFGLN 497
Fly 501 FVPCKELISLSLLLKHNQSTSCSILCLKTLLNILRHNAVFKDVYREVGILEIFVGCLTRYAAHVQ 565
:||||||.|:|:|||.:.|..|||...:|||.:.||:.||.||:||||:||:.|..|.:|||.::
Zfish 498 YVPCKELFSVSVLLKSSTSYGCSITATRTLLKLGRHHPVFSDVFREVGLLEVLVNLLHKYAALLK 562
Fly 566 KIT-----KGDESVVVELENESEEELFDTLGKHVLEALTMLLGGGASNNAQLFREYGGAKCVHEL 625
..| :||.. .|.:||: ..|...|:|.||:|| .|::.||.||||:|||:|||.:
Zfish 563 DPTQTHSDQGDSK-----NNVAEEQ--KQLAWLVMETLTVLL-QGSNTNAGLFREFGGARCVHNI 619
Fly 626 VKFKHCRPQALGIVRELILSAGGDDDMLHILSLMHSVSPLQVEFKIQILNMLLGCLKDSHRTRTV 690
||::.||..||.|:::|:||..|||||..:|.||||....:::.|..||..||..|::|||||||
Zfish 620 VKYRQCREHALMIIQQLVLSPSGDDDMGTLLGLMHSAPTAELQLKTDILRALLAVLRESHRTRTV 684
Fly 691 FRKVGGFVYVTSVFVSLDGSMALPQ----PDIPQQDLILLLQIVFQTLATAMRFEPANAKFFHQE 751
||||||||||||:.::::.|:..|. ..:.|..:..||..:|.||..|||:||||:.||..|
Zfish 685 FRKVGGFVYVTSLLLAMERSLCSPPVIGWEKVNQNKVFELLHTIFCTLTAAMRYEPANSHFFRTE 749
Fly 752 ISSSSLCDTLRLLGCFGGSSALQDYT---GTYEPQQSLLKYYHEIFSGDILSVSFSEDVPYPLSY 813
|....|.|.:||||||..:..:...| ...:|.|.||: .||.. :|:|...|.:
Zfish 750 IQYEKLADAVRLLGCFSDAKKVGPATVFPSNAQPFQRLLE--DEIIP--------AENVCPTLKH 804
Fly 814 VCIVFRLLYSIALDNFEA------PNLSGIITL---FSDPPTTLR-----SPSKELAPPVHPSQL 864
...:|..:|.:|.|:|:: |.|:...:| :..|..|.: |.|...|.....:.|
Zfish 805 CSKLFIYMYKMATDSFDSRAEQVPPCLTHETSLPSPWGTPAITRKSRHGYSSSSNSASGKALTDL 869
Fly 865 -----NLTQPSPEPRIVHPGVVLCMLQLLPAVEYDMAPLQAVQLQVYLSEIIKSLVRSERNQQIM 924
|.:|.|.:|.::|||.||.||.|||:|..|..|..|:.||:.::.|::.||.|||||||:
Zfish 870 KLHLGNSSQHSSDPVVIHPGAVLAMLDLLPSVSSDTQPEHALDLQLAVANILQLLVHSERNQQIL 934
Fly 925 CDHGLAEKLLKLTRRALAEESHPLHVPMQYILERLAAQALQPTELRQFLRLGEPLSCA--DIDLQ 987
|:.||..:||:....||.:|.||||.|:|.:.||||:|||:|..||:|||||.||:|. |..|.
Zfish 935 CEAGLHSRLLQRCSCALGDEDHPLHPPLQRMFERLASQALEPMVLREFLRLGNPLNCGAWDKKLL 999
Fly 988 QPYKL-------------------------------------------------GGPVPLTRIKT 1003
:.|:: |..|||||:|.
Zfish 1000 KQYRVHKPSSLSYEAEMRNSMTLSMEGFGPDSVFTINEDNSQYRISRSLVRSAEGSTVPLTRVKC 1064
Fly 1004 LVSMTTPRDFRAHGSSTLPPFVELDMSAEGFGCLYLPSL----APQATATAGGTIDANSIGGIGA 1064
|||||||.|.|.||||..|.|||||.|.||||||:|||| ||.:.|...|..|...:.|:|.
Zfish 1065 LVSMTTPHDIRLHGSSVTPAFVELDTSLEGFGCLFLPSLAPHNAPSSNANTSGVSDGAVVSGMGN 1129
Fly 1065 GDRIFPPQTGLTYSTWFCVEKFSDPKTDPHCVRLLTLVRTIHNPREENLACLSILLSARDKAIVV 1129
|:|.|||.:||:||||||||:||.| ...|.|||||:||.. ...|::..||:|:|||:|::::|
Zfish 1130 GERFFPPPSGLSYSTWFCVERFSTP-PQSHPVRLLTVVRRA-TSSEQHYVCLAIVLSAKDRSLIV 1192
Fly 1130 STQETLVTPRKSIGDWEPEGSDDGI----ARIWCPDLLHEGQWHNLVVVLNRAVLKNSSLFLYLD 1190
||:|.|: :..:.|:..|.|...| ||..|.||:.|||||:|::|:::.:||||...||:|
Zfish 1193 STKEELL--QSYVDDFSEESSFYEILPCCARFRCADLITEGQWHHLLLVMSKGMLKNSMATLYID 1255
Fly 1191 GVPMHTQKLHYIAQHPAAGNASLTSP--TQIFGYIGTPPIWRRYSRLCWKQGVCHLIEDVLTQQT 1253
|..:.|.||||:...| .|:||...| :.::.||||||..|:.|.|.|:.|..|.:|:||...:
Zfish 1256 GQMVSTVKLHYVHNSP-GGSASANPPVVSTVYSYIGTPPAQRQLSTLVWRLGPTHFLEEVLPAAS 1319
Fly 1254 VQTIYQLGPHYMGSLQA---PQLGKQSESLAP----LVPEDRVLLGLNAKAVSKLTLVKIRKVYS 1311
|..||:|||:|:||.|| |....::|::.| ||||::|...|.|.:||.||:.||||||:
Zfish 1320 VAAIYELGPNYVGSFQAVYLPCKDSKTEAVPPCPVGLVPEEKVSFSLFAHSVSALTVAKIRKVYN 1384
Fly 1312 RADNKSIAKQLNMNSHENATPIKILHNSAGHLAGAGRSLGGVVVGYLGVRVFSPHPVSAMIDTVG 1376
:.|:|:|||||.::|||:|||:|::||:.|||.|:.|::|..|:||||||.|...||:..:..:|
Zfish 1385 KLDSKAIAKQLGVSSHESATPVKLVHNAVGHLNGSARTVGAAVIGYLGVRAFVTKPVATNLQYIG 1449
Fly 1377 GCNVLLGIIAMAQDVESLYAGVKALTCVVRSNRAAQAEMDRKRCYQTLGMFFKKKKHLLNSHILH 1441
|...:||::|||.|||.|||.||||.|||:||..|..||:|.:.||.|.|..|||:.||||||||
Zfish 1450 GAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRPLLNSHILH 1514
Fly 1442 LTFGLVGTVNSGQDMSAIPNVTAFQDLLCDLEIWHNAPNGLLRSLLEHLLELVVESSDKKQNVKI 1506
|||.|||||:||.:.|.|||.|||||||||.|:|.:||..|..||.||.:||:.|||:..:|.|:
Zfish 1515 LTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEAAKNAKL 1579
Fly 1507 MRDLQLLVKLLHIITQIQDHS----TREILFSLLETLLGGQPRHTDLLLFGQYVAAKLPHAHSGG 1567
:|:.||:.||| ..::|.| |...:.::|..||.|.|...|||.|||::::.|| ....
Zfish 1580 LREFQLIPKLL---LTLRDQSLSQPTITAIGNVLSLLLQGFPNTYDLLRFGQFISSTLP--TFAV 1639
Fly 1568 LERAVLLPS-----MKNPAEDQDGGVAQN--IYLRNRCLSLLHGLLFT--PRNTVNYVICDDISK 1623
.|:.|::.: :...|:::.||:..: |.||||.|.:|...||: .:.|||...|:::.:
Zfish 1640 CEKFVIMENTNEEKIDRGADEEFGGLLSSNLILLRNRLLDILLKQLFSCKEKGTVNAQACEELVR 1704
Fly 1624 TLGMDWLLLFMQPHVHFTTVIIAVRILVVICANESFLVRFRDATHNGGYLRFTEMVSQRKMLGLG 1688
|||.||||:||:.|:|.:||..|:.||||:.:|:|.|.||::....||:|..|:.|.
Zfish 1705 TLGFDWLLMFMEEHIHSSTVTAALLILVVLLSNQSILSRFKEGLSGGGWLDHTDSVL-------- 1761
Fly 1689 AQQLNQRPTNGTGTVI------VATPQNTIQHLPTQIAGEVRAAALNIPGFQLLEWLMNHHLDVP 1747
||..|||: .|..::|:: |:...|.:.|||.:|:.|:..|.:||
Zfish 1762 --------TNKIGTVLGFNVGRSAGGRSTLR--------EINRDACHFPGFPVLQTLLPKHTNVP 1810
Fly 1748 ELYFLITALIMGQPVKVLATE-HTKFDLDRVWSFLWGAPVSANTQLPKL-NICPEGVCVLLAMVR 1810
|:||::.||...||:..|... ...||||.:|:|::|.|.|:.|.:..| |:|.|...:||||:|
Zfish 1811 EIYFMLMALFFQQPITELPESLQVHFDLDSIWTFIFGVPASSATVVGSLHNMCTETAFLLLAMLR 1875
Fly 1811 GIVH----GGECAPWLHSHPETIIQLLFSLYQNLTDFAPVMMTGDVVTSLVAVLFPLASRPAD-- 1869
.::: ..|...||..:|.|::|....||.|:.|.||:..:.|.:.:|.|.:||...||..
Zfish 1876 SMLNLPWQSEEEGSWLREYPITLMQFFRYLYHNIPDLAPMWHSPDFLCTLAATVFPFNIRPYSEM 1940
Fly 1870 -SEPNSGASTPTD-------DTGSSFALPPPETLHGAPQPKLTAHPVCNCIIDFLRVIVVDSLGL 1926
|:.:..||:||: |||.:.: ..|..:...:..||.||....:.||:|::::|:|.:
Zfish 1941 VSDLDDEASSPTEEFKAFVTDTGMNRS--QSEYCNVGNKTYLTNHPAKKYVFDFMRLLIMDNLCM 2003
Fly 1927 NMQGKPTPVIDLVLDAAPESAELPLQVQYQTQIIIALMDHLLAADVLVGEQAALPLVPLLQSQMQ 1991
....|.||:|||:|:|:||.:....|.::|:.|:.::|:.|||||||:||:|:||:. .....|
Zfish 2004 TPASKQTPIIDLLLEASPERSTRTQQKEFQSYILDSVMEQLLAADVLMGEEASLPIT--TGGSYQ 2066
Fly 1992 YIAPNVFYLTARIVDKLWQGCLARNPHDIFDFVIKLIVQAKRRSSSLSLEHLHHSLNRSILFLLS 2056
.:..||||.|.|:|||||||...:....:.||:::||.|:||||..|||:.::|.|||:||:.||
Zfish 2067 VLVNNVFYFTQRVVDKLWQGMFNKESKLVVDFIVQLITQSKRRSQGLSLDSVYHCLNRTILYQLS 2131
Fly 2057 RPTDDSRADQMSVLEALHKIIQHRLLIFGAGNHELEFIGCLTYCLLQLTADMKII---LEPATSR 2118
|| ..:...|:::|::|..:..:|.|:.|.|||:.||:.||.:||:.|.....:. || |.:|
Zfish 2132 RP-HKTVPQQVTLLDSLRVLTVNRNLVLGPGNHDQEFVACLAHCLINLHTGSSVEGFGLE-AEAR 2194
Fly 2119 NTTWHVNPQTETAEPKDEDLNQLQGRNLIVGAAFRVWEELYVCKKPAIEEVFKVSLTSPPPNSKA 2183
.|||||...:|......:..:..:||.|::.|..|||.||...|:..:|::||||| |.|.:.
Zfish 2195 MTTWHVAVPSENESDSVQSQDVSEGRQLLLKAVNRVWTELMHSKRQMLEDIFKVSL---PVNDRG 2256
Fly 2184 -PDLQTTREQVMELASKLWFNYVEAERKATYR----APWELHTQIQSKIQKVTG--GLSRLTSRT 2241
.|:.|.|..:.|.|:|.|.|::..|:|...| ||.. |||:.:|:. |||:||...
Zfish 2257 HVDIGTARPALEEPAAKSWQNHLVHEKKCISRGETVAPAN-----QSKLSRVSSGFGLSKLTGSR 2316
Fly 2242 KTKKEELVRTRSTLTREAAYESTGIHVQLIKDLLDLRAKQYQQMLQHTQRYVYQDWVQSEMELTR 2306
::|||..: .::.|:.:..::....|:.:::||:.::.|::|:..|:..:||..:|...|.||.|
Zfish 2317 RSKKESGM-NKNNLSAQETFQWMFTHIAVVRDLVAMQYKEHQERQQNALKYVMDEWAGIEYELLR 2380
Fly 2307 ERGLWGPTGSCSLDKWILDTTEGPHRMRKKTMRNDVFYLHYPYRPE------------------- 2352
|||||||.....|||:.||.||||.|||||.:|||:||:||||.|:
Zfish 2381 ERGLWGPPIGSHLDKFQLDMTEGPCRMRKKMVRNDMFYIHYPYVPDPEPNASTQNDSQVPIMGAM 2445
Fly 2353 LELADNRQLKYKVASSLDSKTYALHGPQQPRILA-EAGEH-HAMQQQSSLEAVQ---SHRLETSS 2412
:.:...:..:|:.|.|.|||.|.: |:|: ..|.: |:::|.:..|..| .|..:|.:
Zfish 2446 INIPVQKPARYRRAISYDSKEYYM------RLLSGNPGMYQHSIEQNTEGETTQQEPEHGEDTIA 2504
Fly 2413 STSTPPPMVLPKLVGHGSTPCPQESVDGNAPEDDEEEE------------DTSMTSDNETFLRLL 2465
... |....|.:.....|...|||.: |....:||.|.||||
Zfish 2505 RVK-------------GLVKAPLKRSRSTADGADEESQDQLQELLESGAMDEEQKTDNTTLLRLL 2556
Fly 2466 EEQEKISFMFRCARVQGLDTFEGLLLFGKEHCYIVDGFTLLKNREIRDIDTLPPGAYEPIIPNSG 2530
||.|||..|:||||||||||.||||||||||.|::||||:...||||||:||||..:|||||...
Zfish 2557 EEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTVTREIRDIETLPPNMHEPIIPRGA 2621
Fly 2531 GTSSTTSRAVSHKLRQCSKFAYEEIREVHKRRYLLQPIALEVFSEDGRNYLLSFPRKVRNKVNQR 2595
..|. |...|.||.||||:|||||||||||||:|.||||.|||||||:|.:.|||||.||
Zfish 2622 RQSK------SQLKRTCSIFAYEDIREVHKRRYLLQPMAAEVFSGDGRNYLLAFQKGVRNKVYQR 2680
Fly 2596 FLALATALNDNAQQSVAGQKRTASVEQTAGIFSGLIGETSVTQRWVRGEISNFQYLMHLNTLAGR 2660
|||:..:|.|:: :||:||:...||||.:|:.|.|:||.||||||.|||||||||||||||||||
Zfish 2681 FLAVVPSLADSS-ESVSGQRPNTSVEQGSGLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGR 2744
Fly 2661 SYNDLMQYPVFPWILADYDSEELDLTNPKTFRDFSRPMGAQAEERLEQFQKRFKEWDDPHGETPP 2725
|||||||||||||||||:|||||||.||||||:.|:|||||.::||.|::||||:|:||:||||.
Zfish 2745 SYNDLMQYPVFPWILADFDSEELDLNNPKTFRNLSKPMGAQTDDRLIQYKKRFKDWEDPNGETPA 2809
Fly 2726 YHYGTHYSSAMIVCSYLVRLEPFSQPFLKLQGGHFDLADRMFHSIKEAWLSASKLNMADVKELIP 2790
|||||||||||||.|||||:|||:|.||:|||||||||||||||::||||||||.||||||||||
Zfish 2810 YHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIP 2874
Fly 2791 EFFYLPEFLSNFNNFDLGTKQNGETLNHVILPPWAKHDPREFIRLHRSALECDYVSQHLHLWIDL 2855
|||||||||.|.||||||:||||..|..||||||||.|||||||:||.||||||||.|||.||||
Zfish 2875 EFFYLPEFLLNSNNFDLGSKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDL 2939
Fly 2856 IFGCKQQGPAAVDAVNVFHHLFYEGNVDIYNIDDPLKKNATIGFINNFGQIPKQLFKKAHPAKKM 2920
|||.|||||.||:||||||||||||.||||||:||||:.|||||||||||||||||||.||.|::
Zfish 2940 IFGYKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRV 3004
Fly 2921 -GGSRHSALIDPTSLIQGNSTVLQTDRLFFHNLDNLKPSLQPIKELKGPVGQILQPDKTVFAVEQ 2984
..|...|...|.:| |||: |::|||:||||:|||.|:||||.|||||:..||.:.||||
Zfish 3005 RSKSNGEAPGGPVTL---NSTL---DKIFFHHLDNLRPSLTPVKELKEPVGQIVCTDKGILAVEQ 3063
Fly 2985 NKVMMPPSYTKYIAWGFADHSLRIGLYDTDRASFVSEASAQNSGEILTCACPNAKMIVTAGTSSV 3049
|||::||::.|..|||:||.|.|:..|::|:|..|.|..:: .|:||...|||.|:::|.|.|:.
Zfish 3064 NKVLVPPAWNKTFAWGYADLSCRLSNYESDKAVVVYECLSE-WGQILCAICPNPKLVITGGFSTA 3127
Fly 3050 VTIWKFDANR---KSLAVKHSLHGHTDAVTCLAASAAYNVIVSGSRDGTAIVWDMTRFTFVRQLR 3111
:.:|:..::: |||.:|.:|.|||||||||.||:||:::||||||.|.|:||:.:.:||.|||
Zfish 3128 ICVWETGSSKEKAKSLTLKQALLGHTDAVTCLTASSAYHIVVSGSRDRTCIIWDLNKLSFVTQLR 3192
Fly 3112 GHAGVVAAVSINELTGDIATCSATWLHVWSINGDALAMVNTCVGSADRMQQILCVAFSQIREWDQ 3176
||...|:|:.||||||||.:|:.|::|||||||..:|..||..| |.|||||...|::.|||.
Zfish 3193 GHRAPVSALCINELTGDIVSCAGTYIHVWSINGSPVASANTFTG---RSQQILCCCVSEMNEWDT 3254
Fly 3177 QNVIITGSTDGVVRMWSLEHTQVPIDRKLKRGTEVSSQDKPDTV-SLEGKDNKDDKMSLMKQIKS 3240
||||:||.:|||||.|.:|..||| :......:...|.||.. .:||:|..|
Zfish 3255 QNVIVTGHSDGVVRFWRIEFLQVP---ETPAPEPIEPPDVPDCCGEIEGRDAPD----------- 3305
Fly 3241 LSQSEEEMEIVKSASESSISEASQHSHGSSKSAEAGPKAEVQGERRKSSISGAKSLHEMKSATVE 3305
|.|..|.|...|....||. |.|:...:.::|..|..|
Zfish 3306 --------------------EDSSESEGEEASLSQEPKP------RSSNSQPSSAVHRPKPRT-- 3342
Fly 3306 GQGSSYDPKSNEDEHAIRPSK--SDTSLTD---GFVVIDNDRHKGDQI----------------- 3348
|:|:...|:.|: |: |||...| |||.:: :...|:
Zfish 3343 --GASWSVDSSSDD-----SRRWSDTLSIDEKEGFVFVN---YSEGQVRPGVPVQPHSQQPSGPS 3397
Fly 3349 --------------------LRKGFRWQRQLMFRSKLTMHTAYDRKDNAEPASITALTVSKDHKI 3393
|:.|:||:|||:||||||||||:||||||.||.||||.:||||..
Zfish 3398 HGPVPQPLQPSTMEARSYNKLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEITALAISKDHSK 3462
Fly 3394 LYVGDARGRIFSWSVTEQPGRGVADHWLKDEGADQCVKCHVKFTLYERKHHCRNCGQVFCNKCSR 3458
:.|||.|||:|||||::||||..||||:|||..|.|..|.|:|:|.||:|||||||||||.||||
Zfish 3463 ILVGDGRGRVFSWSVSDQPGRSTADHWVKDEQVDSCSGCTVRFSLTERRHHCRNCGQVFCQKCSR 3527
Fly 3459 FESEISRLRILKPVRVCQACYSQLR 3483
|:|||.||:|..||||||.||..|:
Zfish 3528 FQSEIKRLKISSPVRVCQNCYYNLQ 3552
| 
