DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TrissinR and Prokr2

DIOPT Version :9

Sequence 1:	NP_001097092.1	Gene:	TrissinR / 33812	FlyBaseID:	FBgn0085410	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_620434.2	Gene:	Prokr2 / 192649	RGDID:	708445	Length:	422	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	78/299 - (26%)
Similarity:	132/299 - (44%)	Gaps:	43/299 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 LLTLLSASTLTAS-ANVTSTISPPINGSSTDYILLYGE--STTSLVP----------ALTTGLSG 157
            |.||..|..|.:: |.:..|..|      |.:|:..|:  ..||..|          .|....|.
  Rat    10 LHTLAPAEVLNSTWAYLPDTYQP------TCHIINMGDQNGNTSFAPDLNPPQDHVSLLPLNYSY 68

  Fly   158 DGSGAVIEDEEDAEKASEYIFDRTDVRIIFITLYTLVFCCCFFGNLLVILVVTLSRRLRSITNFF 222
            ......::|:||..|...:.    ..:|:.......:...|..||.:.|..:...::||::||..
  Rat    69 GDYDIPLDDDEDVTKTQTFF----AAKIVIGVALAGIMLVCGVGNFVFIAALARYKKLRNLTNLL 129

  Fly   223 LANLAFADFCVGLFCVMQNLSIYLIE--SWVFGEFLCRMYQFVHSLSYTASIFILVVICMERYFA 285
            :||||.:||.|.:.|....:..|::.  ||..|..||....::.::|...|...|:.|.::||.|
  Rat   130 IANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLA 194

  Fly   286 IVHPITCKQILTAARLRMVIVTVWITSAVYSTPKFVFSK-----TIKNIHTQDGQEEEIC----V 341
            ||||:  |..:.......:|..||:.|.:.:.|...|:.     .:||      ||:..|    .
  Rat   195 IVHPL--KPRMNYQTASFLIALVWMVSILIAIPSAYFTTETILVIVKN------QEKLFCGQIWP 251

  Fly   342 LDREMFNSKLLDMINFVLLYVMPLLVMTVLYSKIAIALW 380
            :|:::: .|...:..|.|.:|.|::.||:.|::|:..||
  Rat   252 VDQQLY-YKSYFLFVFGLEFVGPVVTMTLCYARISQELW 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TrissinR	NP_001097092.1	7tm_4	191..>327	CDD:304433	40/142 (28%)
TrissinR	NP_001097092.1	7tm_1	201..>385	CDD:278431	56/191 (29%)
Prokr2	NP_620434.2	7tmA_prokineticin-R	92..382	CDD:320332	58/207 (28%)
		TM helix 1	94..118	CDD:320332	4/23 (17%)
		TM helix 2	127..149	CDD:320332	9/21 (43%)
		TM helix 3	167..189	CDD:320332	4/21 (19%)
		TM helix 4	210..226	CDD:320332	4/15 (27%)
		TM helix 5	259..282	CDD:320332	7/22 (32%)
		TM helix 6	312..334	CDD:320332
		TM helix 7	350..375	CDD:320332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910