Protein Alignment CG11034 and DAP2

DIOPT Version :10

• Sequence 1: NP_608961.2
• Gene: CG11034 / 33810
• FlyBaseID: FBgn0031741
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_011893.1
• Gene: DAP2 / 856423
• SGDID: S000001070
• Length: 818
• Species: Saccharomyces cerevisiae
• Alignment Length: 744
• Identity: 227/744 - (30%)
• Similarity: 349/744 - (46%)
• Gaps: 111/744 - (14%)

  Fly    60 WIT---------GTYYTATD-----RSIH--KFNAATKTDVIFQNSSFLNNYVGAT---FSLSPD 105
            ||:         |.|.|..:     :|::  .:|:     |:.:..:|::|....|   .:.|||
Yeast    91 WISDNKIESNDLGLYVTFMNDSYVVKSVYDDSYNS-----VLLEGKTFIHNGQNLTVESITASPD 150

  Fly   106 NTKILIRHNLTEKFRHSYIAQYDVFDIETNTTVQIHKGEKLQYCGWSPLRDRLAYVYLNNVFIH- 169
            ..::|||.|..:.:|||....|.|:|..:::..:|  |.::....|||..:.:|||..||::|:
Yeast   151 LKRLLIRTNSVQNWRHSTFGSYFVYDKSSSSFEEI--GNEVALAIWSPNSNDIAYVQDNNIYIYS 213

  Fly   170 -FSESLEISITDDGVDGVVYNGVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVETF--TY 231
             .|:....::|:|| ...::||.|||||||||.....|.|||..|..||....:::||..|  .|
Yeast   214 AISKKTIRAVTNDG-SSFLFNGKPDWVYEEEVFEDDKAAWWSPTGDYLAFLKIDESEVGEFIIPY 277

  Fly   232 FLYGDGATTFYQYPHEEQLKYPKSGSKNPVVSLRVYDVSD----------NDPTMHTIVAPVDIV 286
            ::..:...    ||....:||||||:.||...|.||.:.|          |......::..|..|
Yeast   278 YVQDEKDI----YPEMRSIKYPKSGTPNPHAELWVYSMKDGTSFHPRISGNKKDGSLLITEVTWV 338

  Fly   287 GDDHILQSVVWSNS---THLLITWMNRRQNLTSIQSCSYEGDCVEV----------KRLEEP-QG 337
            |:.::|......:|   |..||..:.:..|:  :::.|..|...|:          :..:.| .|
Yeast   339 GNGNVLVKTTDRSSDILTVFLIDTIAKTSNV--VRNESSNGGWWEITHNTLFIPANETFDRPHNG 401

  Fly   338 WVDISTPKCLSTGKSCIFGYFIDNWHQVWNLDLETGLNSWQSRGNFTVLSVYGYDEARDKLYYQA 402
            :|||     |..|......|| :|.:......|..|  .|:     .|.....:|...::||:.:
Yeast   402 YVDI-----LPIGGYNHLAYF-ENSNSSHYKTLTEG--KWE-----VVNGPLAFDSMENRLYFIS 453

  Fly   403 TLPG--DPSVYHV--FSNDECLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPSYTRIFE- 462
            |...  :..||::  .|.:|.:.......||.    ...:||....:..|:..||...|.:|.:
Yeast   454 TRKSSTERHVYYIDLRSPNEIIEVTDTSEDGV----YDVSFSSGRRFGLLTYKGPKVPYQKIVDF 514

  Fly   463 ASTKTLQVD-----------WEPNTAYRKQIEEKLRPSYRFMNVTLADGSIGYAKLA-----LPP 511
            .|.|..:.|           .|.|....|.:|:...|...|..:.|.....|...|.     ||.
Yeast   515 HSRKAEKCDKGNVLGKSLYHLEKNEVLTKILEDYAVPRKSFRELNLGKDEFGKDILVNSYEILPN 579

  Fly   512 NFVET--KKYPLIVVVYQGPNSVRVTNGFTLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVN 574
            :|.||  ..||:....|.||||.:|...|::|:...|.:..:.|...:||||||.||:|....|.
Yeast   580 DFDETLSDHYPVFFFAYGGPNSQQVVKTFSVGFNEVVASQLNAIVVVVDGRGTGFKGQDFRSLVR 644

  Fly   575 NDLGDHEVEDQLFVTRWMQQNLAFVDAERCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTS 639
            :.|||:|..||:.... :..:|.|||.::..::|||||||:|.||:|||..|.|:.|:||||||.
Yeast   645 DRLGDYEARDQISAAS-LYGSLTFVDPQKISLFGWSYGGYLTLKTLEKDGGRHFKYGMSVAPVTD 708

  Fly   640 WLYYDTIYTERYMGLPTDDDNLKKYNESSVFGNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLL 704
            |.:||::||||||..|  .:|...|.||||.......:::.|||:||:||||||:|:||....||
Yeast   709 WRFYDSVYTERYMHTP--QENFDGYVESSVHNVTALAQANRFLLMHGTGDDNVHFQNSLKFLDLL 771

  Fly   705 QRQDIQ-FEEQTYTDENHGIGNALPHLYH 732
            ....:: ::...:.|.:|.|      .||
Yeast   772 DLNGVENYDVHVFPDSDHSI------RYH 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_608961.2	DPPIV_N	103..457	CDD:395744	106/385 (28%)
		Peptidase_S9	538..745	CDD:459761	83/196 (42%)
DAP2	NP_011893.1	DPPIV_N	148..508	CDD:395744	106/385 (28%)
		Peptidase_S9	608..815	CDD:459761	83/196 (42%)