DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11034 and zgc:136971

DIOPT Version :9

Sequence 1:	NP_001285638.1	Gene:	CG11034 / 33810	FlyBaseID:	FBgn0031741	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_017212859.1	Gene:	zgc:136971 / 678599	ZFINID:	ZDB-GENE-060421-3674	Length:	952	Species:	Danio rerio

Alignment Length:	804	Identity:	148/804 - (18%)
Similarity:	259/804 - (32%)	Gaps:	230/804 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PRPSTAAAVIGRVDGAEGNK------TAWELTEALYGTSGLRSFNGTWITGTYYTATDRSIHKFN 77
            |.|.:|:.:...:......|      |.|...:...|..  ..|:.||   |.....|...|...
Zfish   254 PVPISASVIADELLDTANKKRCITVLTRWSQCDLERGVK--LQFSKTW---TLLCKHDTVEHVLP 313

  Fly    78 AATKTDVIFQNSSFLNNYVGATFSLSPDNT-KILIRHNLTEKFRHSYIAQYDVFDIE-------T 134
            :.|.:.:   .:..|:       ..||..| :.:||    .:..|.|:..:....:|       .
Zfish   314 SGTSSQI---ENELLS-------CQSPSGTLQAVIR----AEAGHQYLEVWGQNGLEKSLDLTAL 364

  Fly   135 NTTVQIHKGEKLQYCGWSPLRDRLAYVYLN-----NVFIHFSESLE-------------ISITD- 180
            |...::::..:.....|||...:|.||...     :|...|..:.|             :.:.|
Zfish   365 NKHGRVYEDAQFGCLAWSPCEKKLLYVAEKKRVEPSVHSSFGSANEDGGLVLLEEQDKNVYVEDW 429

  Fly   181 -DGVDG----------------VVYNGVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVET 228
             :|:.|                ::|.|||..:      |...|:|..:....:.||.:|:
Zfish   430 GEGLVGKSSPVLCVADLNKATVIIYAGVPPHI------SPAQALWAPNGRGVVFVGLWNE----- 483

  Fly   229 FTYFLYGDGATTFYQYPHEEQLKYPKSGSKNPVVSLRVYDVSDN------------DPTMH---- 277
                            |....||:    ..|...:|...|:..|            .|.|.
Zfish   484 ----------------PFRLGLKF----CSNRRSALYYLDMKGNCECLSSDGMSVSSPRMSPDSC 528

  Fly   278 -TIVAPVDIVGDDHILQSVVWSNSTHLLITWMNRRQNLTSIQSCSYEGDCVEVKRLEEPQGWVDI 341
             .:....::.|..|...|:       :|....||..::           .|:|.|..|...:..|
Zfish   529 WIVYLQGEVFGPHHQCLSM-------MLYDMKNRSSSV-----------LVDVIRRAEKGQFAGI 575

  Fly   342 --STPK-CLST-GKSCIFGYFIDNWHQVWNLDLETGLNSWQSRGNFTVLSVYGYDEARDKLYYQA 402
              |.|. |.|. .:...|....:|...|:::|..||          .::.|.|.|..|
Zfish   576 YESLPSHCWSADSERVFFSSACENKKAVFSVDRTTG----------KIIQVCGLDVLR------- 623

  Fly   403 TLPGDPSVYHVFSNDECLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPS-------YTRI 460
                    ...|.:.:.|                 |..|..  ..|||:.||..       .:::
Zfish   624 --------LDDFGSVQLL-----------------TIQKDL--MVLSCSSPNQPPCLRAGFLSKV 661

  Fly   461 FEASTKTLQ----------VDWEPNTAYRKQIEEKLRPSYRFMNVTLADGSIGYAKLALPPNFVE 515
            ..|....|.          .||:|........||    :::|..:..  |:| ..|...||   |
Zfish   662 NRAEDMQLSNLGGADVYEGFDWQPMLITPPSQEE----NHQFSGLNF--GAI-LLKPYSPP---E 716

  Fly   516 TKKYPLIVVVYQGPNSVRVTNGFTLGYEAFVTTSRDTIYA--YIDGRGTGNKGKDLLFSVNNDLG 578
            .:|.||:|.::.||::     .|...:.|.........:|  .::.||:...|:|.:.|:..::|
Zfish   717 RRKTPLVVNIHGGPHA-----HFAADWNATAAALTKLGFAVLMVNYRGSTGFGQDSIESLLGNVG 776

  Fly   579 DHEVEDQLFVTRWMQQNLAFVDAERCGIWGWSYGGYMTAKTIEKDDDRVFQCG-----------V 632
            ..:|:|.........||...:|.:|..:.|.|:||::....|.:..|....|.           :
Zfish   777 SQDVKDVQRAVLCALQNETTLDPDRVVVMGGSHGGFLACHLIGQYPDFYRACAARNPVINAATLL 841

  Fly   633 SVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNESSVFGNLENFKSHDFLLIHGSGDDNVHYQHS 697
            ..:.:..|.|........:..|||....:...::|.:. :....:: ..||:.|..|..|.....
Zfish   842 GTSDIVDWRYSSVGLQYAFDRLPTSQSLISMLDKSPII-HAPQIRA-PVLLMLGGRDRRVSPHQG 904

  Fly   698 LLLAKLLQRQDIQFEEQTYTDENH 721
            |.|.:.|:.::.......::||.|
Zfish   905 LELYRALKSRNTPVRLLWFSDEGH 928

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_001285638.1	DPPIV_N	103..457	CDD:279298	74/425 (17%)
CG11034	NP_001285638.1	Peptidase_S9	538..745	CDD:278741	39/197 (20%)
zgc:136971	XP_017212859.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1506
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810