Protein Alignment CG11034 and dpp2

DIOPT Version :10

• Sequence 1: NP_608961.2
• Gene: CG11034 / 33810
• FlyBaseID: FBgn0031741
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_593970.1
• Gene: dpp2 / 2542415
• PomBaseID: SPACUNK4.08
• Length: 793
• Species: Schizosaccharomyces pombe
• Alignment Length: 675
• Identity: 212/675 - (31%)
• Similarity: 338/675 - (50%)
• Gaps: 64/675 - (9%)

  Fly    99 TFSLSPDNTKILIRHNLTEKFRHSYIAQYDVFDIET---NTTVQIHKGEKLQYCGWSPLRDRLAY 160
            ::|:|.|...:|:..|.::::|||..|||.:::.||   |...|.::...:....|||...:|::
pombe   121 SYSISFDAKYVLVSVNKSQRWRHSSFAQYYLYNTETKDVNMLGQDNEHWTISLAEWSPTGHQLSF 185

  Fly   161 VYLNNVFIHFSESLEISITDDG-VDGVVYNGVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDT 224
            ||.|::::..::.....:|.|| ||  |:||:.||:||||||||.|.||||.|..::|....|::
pombe   186 VYNNDLYVRKNDGNVQRLTYDGTVD--VFNGLTDWIYEEEVLSSPSTIWWSPDSDKIAFLKLNES 248

  Fly   225 EVETFTYFLYG---DGATTFYQYPHEEQLKYPKSGSKNPVVSLRVYDVSDNDPTMHTIVAPVDIV 286
            |:.|:.|.||.   |.:...:.|..:..:||||.|:.||.|||.|.|::.|..:..::.....:.
pombe   249 EIPTYHYPLYTAELDPSLPEFDYNKDMAIKYPKPGNPNPSVSLFVADLNSNASSNFSLWHNEPLA 313

  Fly   287 GDDHILQSVVWSNSTHLLITWMNRRQ----------NLTSIQSCSYEGDCVEVKRLEEPQGWVDI 341
              :.::|:|:|.|::.:|:.:.||..          .|.||.:...|  |:|       :||.::
pombe   314 --EPVVQNVLWVNTSSVLVQFTNRNSTCITARLLDTELKSIHTVKTE--CLE-------EGWYEV 367

  Fly   342 -STPKCLSTGKSCIFGYFIDNWHQVWNLDLETGLNSWQSRGNFTVLSVYGYDEARD--------- 396
             .:.|......|.::..:.|.:..:..||....|......|:..:....|..:..|
pombe   368 QQSAKMFPLNNSLVWENWSDGYFDILALDDYNHLAFIPFNGSSPIYLTSGAWDVTDGPIHIDGDF 432

  Fly   397 -KLYYQATLPGDPSVYHVFSNDECLSCGQIDADGAACRSASGTFSKSFS----YYTLSCTGPNPS 456
             .:|:.|||......:..:.:.:.|....|..:|    ...|.:|.|||    :|.|:..||:..
pombe   433 GNVYFLATLKDSTERHLYYVSLDTLEIYGITDNG----EDEGYYSTSFSPFGDFYVLNYHGPDVP 493

  Fly   457 YTRIFEASTKTLQVDWEPNTAYRKQIEEKLRPSYRFMNVTLADGSIGYAKLALPPNFVETKKYPL 521
            :..:.....|...:..|.|:..::|:.....||..:..:|..|.:..:.: ..|.||...||||:
pombe   494 WQELRSTKDKDYCLSLETNSRLKQQLSSITLPSVEYGKLTFNDTTFNFME-RRPRNFDVNKKYPV 557

  Fly   522 IVVVYQGPNSVRVTNGFTLGYEAFVTTSRD--TIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVED 584
            :...|.||.|.:|...|.:.::|::.:..|  .|...:||||||..|....:||:..||:.|..|
pombe   558 LFFAYGGPGSQQVAKLFRVDFQAYLASHPDFEFIVVTLDGRGTGFNGNAFRYSVSRHLGEWESYD 622

  Fly   585 QLFVTR-WMQQNLAFVDAERCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYT 648
            |....: |  .:|.|||....||||||||||:|.||:|..|  ||..|::|||||.|..||::||
pombe   623 QGQAGKFW--ADLPFVDENHVGIWGWSYGGYLTLKTLETQD--VFSYGMAVAPVTDWRLYDSVYT 683

  Fly   649 ERYMGLPTDDDNLKKYNESSVFGNLENFKS-HDFLLIHGSGDDNVHYQHSL-LLAKLLQRQDIQF 711
            ||||.||  ..|.:.|..|.:. :.|.||. ..|.:.||:||||||:|||: |:..|.......:
pombe   684 ERYMDLP--QYNKEGYKNSQIH-DYEKFKQLKRFFVAHGTGDDNVHFQHSMHLMDGLNLANCYNY 745

  Fly   712 EEQTYTDENHGIG--NALPHLYHTI 734
            :...:.|..|.|.  ||...:||.:
pombe   746 DMAVFPDSAHSISYHNASLSIYHRL 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_608961.2	DPPIV_N	103..457	CDD:395744	107/385 (28%)
		Peptidase_S9	538..745	CDD:459761	84/204 (41%)
dpp2	NP_593970.1	DPPIV_N	125..494	CDD:395744	107/385 (28%)
		Peptidase_S9	574..779	CDD:459761	84/204 (41%)