Protein Alignment CG11034 and Dpp4

DIOPT Version :10

• Sequence 1: NP_608961.2
• Gene: CG11034 / 33810
• FlyBaseID: FBgn0031741
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_036921.2
• Gene: Dpp4 / 25253
• RGDID: 2515
• Length: 767
• Species: Rattus norvegicus
• Alignment Length: 784
• Identity: 261/784 - (33%)
• Similarity: 407/784 - (51%)
• Gaps: 78/784 - (9%)

  Fly     8 ITAFGLFITVCPRPSTAAAVIGRVDGAEGNKTAWELTEALYGTSGLRSFNGTWITGT-YYTATDR 71
            :.|....|||      ...::.:.:.|..::..:.|.:.|..|..::|::..|::.: |....:.
  Rat    14 VAALVTIITV------PVVLLNKDEAAADSRRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQEN 72

  Fly    72 SIHKFNAATKTDVIF-QNSSF------LNNYVGATFSLSPDNTKILIRHNLTEKFRHSYIAQYDV 129
            :|..|||......|| :||:|      :::|     |:|||...:|:.:|..:::||||.|.|.:
  Rat    73 NILLFNAEHGNSSIFLENSTFEIFGDSISDY-----SVSPDRLFVLLEYNYVKQWRHSYTASYSI 132

  Fly   130 FDIETNTTVQIHKGEKL----QYCGWSPLRDRLAYVYLNNVFIHFSESL-EISITDDGVDGVVYN 189
            :|:...   |:...||:    |:..||....:||||:.|::::.....| ...||..|.:.|::|
  Rat   133 YDLNKR---QLITEEKIPNNTQWITWSQEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFN 194

  Fly   190 GVPDWVYEEEVLSSGSAIWWSSDGSRLAVGFFNDTEVETFTYFLYGDGATTFYQYPHEEQLKYPK 254
            |:.|||||||:..:.||:|||.:|:.||...||||.|....|..|.|.:   .|||....:.|||
  Rat   195 GINDWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVPLIEYSFYSDES---LQYPKTVWIPYPK 256

  Fly   255 SGSKNPVVSLRVYDVSDNDPTMHT----IVAPVDIVGDDHILQSVVWSNSTHLLITWMNRRQNLT 315
            :|:.||.|...:.:......|..|    |.||..:...||.|..|.|.:...:.:.|:.|.||.:
  Rat   257 AGAVNPTVKFFIVNTDSLSSTTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYS 321

  Fly   316 SIQSCSYE-----GDCVEVKRLEEPQ--GWVD---ISTPKCLSTGKSCIFGYFI----DNWHQVW 366
            .:..|.|:     .:|...:...|..  |||.   .:.|...|.|.|.   |.|    |.:..:.
  Rat   322 VMAICDYDKTNLVWNCPTTQEHIETSATGWVGRFRPAEPHFTSDGSSF---YKIVSDKDGYKHIC 383

  Fly   367 NLDLETGLN---SWQSRGNFTVLSVYGYDEA--RDKLYYQAT----LPGDPSVYHV----FSNDE 418
            ....:....   ::.::|.:.|:|:    ||  .|.|||.:.    :||..::|.:    .:|.:
  Rat   384 QFQKDRKPEQDCTFITKGAWEVISI----EALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKK 444

  Fly   419 CLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPN-PSYTRIFEASTKTLQVDWEPNTAYRKQI 482
            ||||   |.:...|:..|.:.||...||.|.|.||. |.||.......|.|:| .|.|:|..|.:
  Rat   445 CLSC---DLNPERCQYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRV-LEDNSALDKML 505

  Fly   483 EEKLRPSYRFMNVTLADGSIGYAKLALPPNFVETKKYPLIVVVYQGPNSVRVTNGFTLGYEAFVT 547
            ::...||.:...:.|.:....| ::.|||:|.::|||||::.||.||.|.:....|.|.:..::.
  Rat   506 QDVQMPSKKLDFIVLNETRFWY-QMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLA 569

  Fly   548 TSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLAFVDAERCGIWGWSYG 612
            ::.:.|.|..||||:|.:|..::.::|..||..|||||:...|...: :.|||:::..|||||||
  Rat   570 STENIIVASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLK-MGFVDSKQVAIWGWSYG 633

  Fly   613 GYMTAKTIEKDDDRVFQCGVSVAPVTSWLYYDTIYTERYMGLPTDDDNLKKYNESSVFGNLENFK 677
            ||:|:..:..... ||:||::||||:.|.|||::||||||||||.:|||..|..|:|....||||
  Rat   634 GYVTSMVLGSGSG-VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 697

  Fly   678 SHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQFEEQTYTDENHGIGN--ALPHLYHTIDAFWTN 740
            ..::|||||:.|||||:|.|..::|.|....:.|:...||||:|||.:  |..|:|..:..|...
  Rat   698 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMSHFLQQ 762

  Fly   741 CLNL 744
            |.:|
  Rat   763 CFSL 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_608961.2	DPPIV_N	103..457	CDD:395744	120/390 (31%)
		Peptidase_S9	538..745	CDD:459761	92/209 (44%)
Dpp4	NP_036921.2	DPPIV_rep	36..56	CDD:465875	3/19 (16%)
		DPPIV_N	106..479	CDD:395744	119/388 (31%)
		Peptidase_S9	560..764	CDD:459761	90/205 (44%)