Protein Alignment CG11034 and Apeh

DIOPT Version :10

• Sequence 1: NP_608961.2
• Gene: CG11034 / 33810
• FlyBaseID: FBgn0031741
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_036632.1
• Gene: Apeh / 24206
• RGDID: 2125
• Length: 732
• Species: Rattus norvegicus
• Alignment Length: 811
• Identity: 157/811 - (19%)
• Similarity: 268/811 - (33%)
• Gaps: 257/811 - (31%)

  Fly    33 GAEGN--KTAWEL--TEALYGT--SGLRSFNGT-----------WITGTYYTATDRSIHKFN--A 78
            |..||  :|..||  .|:..||  :.||...||           |       ..:|.:..||  |
  Rat    80 GPAGNSVETRGELLSRESPSGTMKAVLRKAGGTVSGEEKQFLEVW-------EKNRKLKSFNLSA 137

  Fly    79 ATKTDVIFQNSSFLNNYVGATFSLSPDNTKILIRHNLTEKFR---HSYIAQYDVFDIETNTTV-- 138
            ..|...::::..|      ...|.|...|.:|.   :.||.|   .|:. |....||..:...
  Rat   138 LEKHGPVYEDDCF------GCLSWSHSETHLLY---VAEKKRPKAESFF-QTKALDISASDDEMA 192

  Fly   139 ------QIHKGEK-LQYCGWSPLRDRLAYVYLNNVFIHFSESLEISITDDGVDG--VVYNGVPDW 194
                  |..||:: :.|..|....              .|:|:.:....|...|  .|..|||
  Rat   193 RPKKPDQAIKGDQFVFYEDWGETM--------------VSKSIPVLCVLDIDSGNISVLEGVP-- 241

  Fly   195 VYEEEVLSSGSAIWWSSDGSRLAVGFFND---------TEVETFTYF---------LYGDGATTF 241
                |.:|.|.|.|...|...:.||::::         |...:..|:         |..||:...
  Rat   242 ----ENVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRYCTNRRSALYYVDLSGGKCELLSDGSLAI 302

  Fly   242 YQ---YPHE---EQLKYPKSGSKNPVVSLRVYDVSDNDPTMHTIVAP--VDIV----GDD----- 289
            ..   .|.:   ..|:||.....:....|.:||       .:|.|..  ||||    |:.
  Rat   303 CSPRLSPDQCRIVYLQYPCLAPHHQCSQLCLYD-------WYTKVTSVVVDIVPRQLGESFSGIY 360

  Fly   290 -HILQSVVWSNSTHLLI--TWMNRRQNLTSIQSCSYEGDCVEVKRLEEPQGWVDISTPKCLSTGK 351
             .:|....||..:..::  :....||:|.::.:                            .||.
  Rat   361 CSLLPLGCWSADSQRVVFDSAQRSRQDLFAVDT----------------------------QTGS 397

  Fly   352 SCIFGYFIDNWHQVWNLDLETGLNSWQSRGNFTVLSVYGYDEARDKLYYQATLPGDPSVYHVFSN 416
            .                   |.|.:..|.|::.:|::     .:|.:..|.:.|..|
  Rat   398 I-------------------TSLTAAGSAGSWKLLTI-----DKDLMVAQFSTPSLP-------- 430

  Fly   417 DECLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPSYTRIFEASTKTLQVDWEPNTAYRKQ 481
             ..|..|.:...|.         .:|.|:.:|....|.|.             :.|.....:...
  Rat   431 -PSLKVGFLPPPGK---------EQSVSWVSLEEAEPIPG-------------IHWGVRVLHPPP 472

  Fly   482 IEEKLRPSYRFMNVTLADGSIGYAKLAL-PPNFVETKKYPLIVVVYQGPNSVRVTNGF------- 538
            .:|         ||..||  :.:..:.| |.|..:..:.|::|:.:.||:|..||...
  Rat   473 DQE---------NVQYAD--LDFEAILLQPSNPPDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLC 526

  Fly   539 TLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLAFVDAER 603
            .:|:...:          ::.||:...|:|.:.|:..::|..:|:|..|....:.|...| ||.|
  Rat   527 KMGFAVLL----------VNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVEQVLQEEHF-DARR 580

  Fly   604 CGIWGWSYGGYMTAKTIEKDDDRVFQC-----GVSVA------PVTSWLYYDTIYTERYMGLPTD 657
            ..:.|.|:||:::...|.:..:....|     .:::|      .:..|...:|       |.|..
  Rat   581 VALMGGSHGGFLSCHLIGQYPETYSACIARNPVINIASMMGSTDIPDWCMVET-------GFPYS 638

  Fly   658 DDNLKKYN------ESSVFGNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDIQFEEQTY 716
            :..|...|      :.|....:...|: ..||:.|..|..|.::..:...:.|:.:::......|
  Rat   639 NSCLPDLNVWEEMLDKSPIKYIPQVKT-PVLLMLGQEDRRVPFKQGMEYYRALKARNVPVRLLLY 702

  Fly   717 TDENHGIGNALPHLYHTIDAFWTNCLNLDVY 747
            ...||    ||..:....|:|....|.|..:
  Rat   703 PKSNH----ALSEVEAESDSFMNAVLWLHTH 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_608961.2	DPPIV_N	103..457	CDD:395744	75/405 (19%)
		Peptidase_S9	538..745	CDD:459761	44/230 (19%)
Apeh	NP_036632.1	APEH_N	<86..285	CDD:466026	51/235 (22%)
		TolB	277..>410	CDD:440585	30/186 (16%)
		DAP2	494..731	CDD:441115	52/259 (20%)