Protein Alignment CG11034 and Apeh

DIOPT Version :10

• Sequence 1: NP_608961.2
• Gene: CG11034 / 33810
• FlyBaseID: FBgn0031741
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_666338.2
• Gene: Apeh / 235606
• MGIID: 88041
• Length: 732
• Species: Mus musculus
• Alignment Length: 818
• Identity: 156/818 - (19%)
• Similarity: 263/818 - (32%)
• Gaps: 277/818 - (33%)

  Fly    21 PS-TAAAVIGRVDGAEGNK-----TAWELTEALYGTSGLRSFNGTWITGTYYTATDRSIHKFNAA 79
            || |..||:.:..||...:     ..||....      |:|||                  .:|.
Mouse    98 PSGTMKAVLRKAGGAVSGEEKQFLEVWEKNRK------LKSFN------------------LSAL 138

  Fly    80 TKTDVIFQNSSFLNNYVGATFSLSPDNTKILIRHNLTEKFR---HSYIAQYDVFDIETNTTV--- 138
            .|...::::..|      ...|.|...|.:|.   :.||.|   .|:. |....|:..:...
Mouse   139 EKHGPVYEDDCF------GCLSWSHSETHLLY---VAEKKRPKAESFF-QTKALDVSASDEEMAR 193

  Fly   139 -----QIHKGEK-LQYCGWSPLRDRLAYVYLNNVFIHFSESLEISITDDGVDG--VVYNGVPDWV 195
                 |..||:: :.|..|....              .|:|:.:....|...|  .|..|||
Mouse   194 PKKPDQAIKGDQFVFYEDWGETM--------------VSKSIPVLCVLDIESGNISVLEGVP--- 241

  Fly   196 YEEEVLSSGSAIWWSSDGSRLAVGFFND---------TEVETFTYF------------------- 232
               |.:|.|.|.|...|...:.||::::         |...:..|:
Mouse   242 ---ENVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRYCTNRRSALYYVDLSGGKCELLSDESLAVC 303

  Fly   233 ---LYGDGATTFYQYPHEEQLKYPKSGSKNPVVSLRVYDVSDNDPTMHTIVAP--VDIV----GD 288
               |..|.....|       |:||.....:....|.:||       .:|.|..  ||||    |:
Mouse   304 SPRLSPDQCRVVY-------LQYPSLAPHHQCSQLFLYD-------WYTKVTSLVVDIVPRQLGE 354

  Fly   289 D------HILQSVVWS-NSTHLLITWMNR-RQNLTSIQSCSYEGDCVEVKRLEEPQGWVDISTPK 345
            .      .:|....|| :|..::...:.| ||:|.::.:
Mouse   355 SFSGIYCSLLPLGCWSADSQRVVFDSVQRSRQDLFAVDT-------------------------- 393

  Fly   346 CLSTGKSCIFGYFIDNWHQVWNLDLETGLNSWQSRGNFTVLSVYGYDEARDKLYYQATLPGDPSV 410
              .||.                   .|.|.:..|.|::.:|::     .||.:..|.:.|..|
Mouse   394 --QTGS-------------------VTSLTAGGSAGSWKLLTI-----DRDLMVAQFSTPNLP-- 430

  Fly   411 YHVFSNDECLSCGQIDADGAACRSASGTFSKSFSYYTLSCTGPNPSYTRIFEASTKTLQVDWEPN 475
                   ..|..|.:...|.         .:|.|:.:|....|.|             .:.|...
Mouse   431 -------PSLKVGFLPPAGK---------EQSVSWVSLEEAEPIP-------------DIHWGIR 466

  Fly   476 TAYRKQIEEKLRPSYRFMNVTLADGSIGYAKLAL-PPNFVETKKYPLIVVVYQGPNSVRVTNGF- 538
            ..:....:|         ||..||  :.:..:.| |.|..:..:.|::|:.:.||:|..||...
Mouse   467 VLHPPPDQE---------NVQYAD--LDFEAILLQPSNSPDKSQVPMVVMPHGGPHSSFVTAWML 520

  Fly   539 ------TLGYEAFVTTSRDTIYAYIDGRGTGNKGKDLLFSVNNDLGDHEVEDQLFVTRWMQQNLA 597
                  .:|:...:          ::.||:...|:|.:.|:..::|..:|:|..|..:.:.|...
Mouse   521 FPAMLCKMGFAVLL----------VNYRGSTGFGQDSILSLPGNVGHQDVKDVQFAVQQVLQEEH 575

  Fly   598 FVDAERCGIWGWSYGGYMTAKTIEKDDDRVFQCGVSVAPVTS------------WLYYDTIYTER 650
            | ||.|..:.|.|:||:::...|.:..:....| ::..||.:            |...:|
Mouse   576 F-DARRVALMGGSHGGFLSCHLIGQYPETYSAC-IARNPVINIVSMMGTTDIPDWCMVET----- 633

  Fly   651 YMGLPTDDDNLKKYN------ESSVFGNLENFKSHDFLLIHGSGDDNVHYQHSLLLAKLLQRQDI 709
              |.|..:|.|...|      :.|....:...|: ..||:.|..|..|.::..|.....|:.:::
Mouse   634 --GFPYSNDYLPDLNVLEEMLDKSPIKYIPQVKT-PVLLMLGQEDRRVPFKQGLEYYHALKARNV 695

  Fly   710 QFEEQTYTDENHGIGNALPHLYHTIDAFWTNCLNLDVY 747
            ......|....|    ||..:....|:|....|.|..:
Mouse   696 PVRLLLYPKSTH----ALSEVEVESDSFMNTVLWLHTH 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11034	NP_608961.2	DPPIV_N	103..457	CDD:395744	76/412 (18%)
		Peptidase_S9	538..745	CDD:459761	46/231 (20%)
Apeh	NP_666338.2	APEH_N	<86..285	CDD:466026	49/240 (20%)
		TolB	277..>410	CDD:440585	31/193 (16%)
		DAP2	481..731	CDD:441115	58/275 (21%)